JP6026659B2 - 神経成長因子が中高年男性の性機能低下症候群を治療するための薬物の調製における応用 - Google Patents
神経成長因子が中高年男性の性機能低下症候群を治療するための薬物の調製における応用 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Description
Claims (3)
- SEQ ID No:1〜3のいずれかで表されるアミノ酸配列からなるポリペプチドを含む神経成長因子の、中高年男性性機能低下症候群を治療するための点鼻型薬物の調製における応用であって、前記点鼻型薬物は点鼻投与方式で中高年男性の性機能低下症候群へ投与される、前記応用。
- 前記薬物は、有効量の前記神経成長因子の外、さらに老年男性性機能低下症候群の治療に有効な一種又は多種の他の薬物活性成分を含む請求項1に記載の応用。
- 他の薬物活性成分が黄体形成ホルモン、又は血小板由来成長因子AAである、請求項2に記載の応用。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201210545427 | 2012-12-14 | ||
CN201210545427.0 | 2012-12-14 | ||
CN201310004439.7A CN103861087B (zh) | 2012-12-14 | 2013-01-07 | 神经生长因子在制备用于治疗中老年男性性功能低下综合征的药物中的用途 |
CN201310004439.7 | 2013-01-07 | ||
PCT/CN2013/089052 WO2014090152A1 (zh) | 2012-12-14 | 2013-12-11 | 神经生长因子在制备用于治疗中老年男性性功能低下综合征的药物中的用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2015525787A JP2015525787A (ja) | 2015-09-07 |
JP6026659B2 true JP6026659B2 (ja) | 2016-11-16 |
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ID=50900475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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JP2015525731A Active JP6026659B2 (ja) | 2012-12-14 | 2013-12-11 | 神経成長因子が中高年男性の性機能低下症候群を治療するための薬物の調製における応用 |
Country Status (3)
Country | Link |
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JP (1) | JP6026659B2 (ja) |
CN (1) | CN103861087B (ja) |
WO (1) | WO2014090152A1 (ja) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105255826B (zh) * | 2015-11-27 | 2019-01-08 | 中山大学 | 人iPS细胞向睾丸间质细胞的诱导分化方法及其用途 |
CN107375910B (zh) * | 2017-07-12 | 2020-03-24 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | PTHrP在制备治疗男性性腺功能低下综合征中的应用 |
CN112439053A (zh) * | 2019-08-29 | 2021-03-05 | 江苏中新医药有限公司 | 一种蛋白长效制剂改善性功能障碍的用途 |
CN111057708B (zh) * | 2020-01-02 | 2022-02-15 | 广州佰斯伦医疗器械有限公司 | 一种核酸及其在治疗或改善男性代谢综合征中的应用 |
CN111514279B (zh) * | 2020-06-16 | 2023-07-18 | 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) | 神经营养因子3在制备治疗男性性腺功能减退症的药物中的应用 |
CN112316121A (zh) * | 2020-11-24 | 2021-02-05 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 胰高血糖素样肽-1在制备治疗男性性腺功能低下综合征药物中的应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1167463C (zh) * | 2000-10-17 | 2004-09-22 | 云南中科云药有限公司 | 治疗外周神经系统疾病和男性生殖缺陷的药品的制备方法 |
WO2002096195A1 (en) * | 2001-05-31 | 2002-12-05 | Enteromed, Inc. | Treatment or replacement therapy using transgenic stem cells delivered to the gut |
WO2007149548A2 (en) * | 2006-06-22 | 2007-12-27 | Medistem Laboratories, Inc. | Treatment of erectile dysfunction by stem cell therapy |
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2013
- 2013-01-07 CN CN201310004439.7A patent/CN103861087B/zh active Active
- 2013-12-11 JP JP2015525731A patent/JP6026659B2/ja active Active
- 2013-12-11 WO PCT/CN2013/089052 patent/WO2014090152A1/zh active Application Filing
Also Published As
Publication number | Publication date |
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WO2014090152A1 (zh) | 2014-06-19 |
CN103861087A (zh) | 2014-06-18 |
CN103861087B (zh) | 2016-04-20 |
JP2015525787A (ja) | 2015-09-07 |
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