JP6012716B2 - 乾燥粉末バンコマイシン組成物および関連する方法 - Google Patents
乾燥粉末バンコマイシン組成物および関連する方法 Download PDFInfo
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- JP6012716B2 JP6012716B2 JP2014511611A JP2014511611A JP6012716B2 JP 6012716 B2 JP6012716 B2 JP 6012716B2 JP 2014511611 A JP2014511611 A JP 2014511611A JP 2014511611 A JP2014511611 A JP 2014511611A JP 6012716 B2 JP6012716 B2 JP 6012716B2
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- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
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- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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| US61/487,971 | 2011-05-19 | ||
| PCT/US2012/038775 WO2012159103A1 (en) | 2011-05-19 | 2012-05-21 | Dry powder vancomycin compositions and associated methods |
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| JP2014515356A JP2014515356A (ja) | 2014-06-30 |
| JP2014515356A5 JP2014515356A5 (es) | 2015-06-18 |
| JP6012716B2 true JP6012716B2 (ja) | 2016-10-25 |
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| JP (1) | JP6012716B2 (es) |
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| IL (1) | IL229506B (es) |
| MX (1) | MX346244B (es) |
| SG (1) | SG195038A1 (es) |
| WO (1) | WO2012159103A1 (es) |
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| US8226975B2 (en) | 2005-12-08 | 2012-07-24 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| ES2743039T3 (es) * | 2012-11-29 | 2020-02-18 | Insmed Inc | Formulaciones de vancomicina estabilizada |
| AU2014205483B2 (en) | 2013-01-10 | 2017-11-30 | Gilead Sciences, Inc. | Non-selective kinase inhibitors |
| CN104043104B (zh) * | 2013-03-15 | 2018-07-10 | 浙江创新生物有限公司 | 含盐酸万古霉素的喷雾干粉及其工业化制备方法 |
| CN111743901B (zh) | 2013-10-11 | 2023-09-12 | 普尔莫凯恩股份有限公司 | 喷雾干燥制剂 |
| CN106029079A (zh) * | 2014-02-28 | 2016-10-12 | 阿尔吉法玛公司 | 藻酸盐低聚物在治疗囊性纤维化和与缺陷性cftr离子通道功能相关的其它疾病中的应用 |
| US10959946B2 (en) | 2014-03-14 | 2021-03-30 | Azurity Pharmaceuticals, Inc. | Composition and method for vancomycin oral liquid |
| SI3142643T1 (sl) | 2014-05-15 | 2019-11-29 | Insmed Inc | Postopki za zdravljenje pljučnih netuberkuloznih mikobakterijskih infekcij |
| SG11201703568WA (en) | 2014-11-06 | 2017-05-30 | Xellia Pharmaceuticals Aps | Glycopeptide compositions |
| WO2016127087A1 (en) | 2015-02-06 | 2016-08-11 | Latitude Pharmaceuticals, Inc. | Aqueous solution formulations of vancomycin |
| GB201609940D0 (en) * | 2016-06-07 | 2016-07-20 | Novabiotics Ltd | Microparticles |
| KR102543227B1 (ko) | 2016-10-27 | 2023-06-13 | 풀모킨 인코포레이티드 | 폐고혈압을 치료하기 위한 병용 요법 |
| CN106963939A (zh) * | 2017-03-22 | 2017-07-21 | 永信药品工业（昆山）股份有限公司 | 盐酸万古霉素药物组合物及其制备方法 |
| CA3062570A1 (en) * | 2017-05-22 | 2018-11-29 | Insmed Incorporated | Lipo-glycopeptide cleavable derivatives and uses thereof |
| US11571386B2 (en) | 2018-03-30 | 2023-02-07 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| WO2020081599A1 (en) * | 2018-10-15 | 2020-04-23 | Savara Inc. | Separation of vancomycin and its degradation products |
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| GR79615B (es) | 1982-10-08 | 1984-10-31 | Glaxo Group Ltd | |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| US4811731A (en) | 1985-07-30 | 1989-03-14 | Glaxo Group Limited | Devices for administering medicaments to patients |
| JPH03193735A (ja) * | 1989-12-22 | 1991-08-23 | Shionogi & Co Ltd | グリコペプチド系抗生物質の安定化組成物 |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| JP4142149B2 (ja) * | 1997-07-10 | 2008-08-27 | 明治製菓株式会社 | バンコマイシンの凍結乾燥製剤 |
| US6586008B1 (en) * | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
| WO2001032144A1 (en) * | 1999-10-29 | 2001-05-10 | Inhale Therapeutic Systems, Inc. | Dry powder compositions having improved dispersivity |
| DE60227691D1 (de) * | 2001-11-01 | 2008-08-28 | Nektar Therapeutics | Sprühtrocknungsverfahren |
| DE10358387A1 (de) * | 2003-12-13 | 2005-07-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulver enthaltend niedermolekulares Dextran und Verfahren zu deren Herstellung |
| FR2872044B1 (fr) * | 2004-06-28 | 2007-06-29 | Flamel Technologies Sa | Formulation pharmaceutique a base d'antibiotique sous forme microcapsulaire |
| EP2050437A1 (en) * | 2007-10-15 | 2009-04-22 | Laboratoires SMB | Improved pharmaceutical dry powder compositions for inhalation. |
| MX345158B (es) * | 2008-10-07 | 2017-01-18 | Raptor Pharmaceuticals Inc | Formulaciones de fluoroquinolona en aerosol para farmacocinetica mejorada. |
| EP3184099A1 (en) * | 2009-03-26 | 2017-06-28 | Pulmatrix, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| CA2754677A1 (en) * | 2009-03-26 | 2010-09-30 | Pulmatrix, Inc. | Methods for treating and preventing pneumonia and ventilator-associated tracheobronchitis |
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2836643C (en) | 2017-11-14 |
| KR20140032450A (ko) | 2014-03-14 |
| MX346244B (es) | 2017-03-13 |
| SG195038A1 (en) | 2013-12-30 |
| CA2981038A1 (en) | 2012-11-22 |
| WO2012159103A1 (en) | 2012-11-22 |
| NZ704819A (en) | 2016-05-27 |
| IL229506B (en) | 2019-07-31 |
| NZ618002A (en) | 2015-03-27 |
| EP2709646A4 (en) | 2015-05-13 |
| JP2014515356A (ja) | 2014-06-30 |
| CN103717231B (zh) | 2016-08-17 |
| CN103717231A (zh) | 2014-04-09 |
| BR112013029803A2 (pt) | 2017-01-17 |
| BR112013029803B1 (pt) | 2021-07-13 |
| MX2013013503A (es) | 2014-05-12 |
| IL229506A0 (en) | 2014-01-30 |
| CA2981038C (en) | 2018-09-25 |
| CA2836643A1 (en) | 2012-11-22 |
| EP2709646A1 (en) | 2014-03-26 |
| AU2012254999B2 (en) | 2016-02-11 |
| KR101763195B1 (ko) | 2017-07-31 |
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