JP6004586B2 - 三糖誘導体及びアジュバントとしてのその使用 - Google Patents
三糖誘導体及びアジュバントとしてのその使用 Download PDFInfo
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- JP6004586B2 JP6004586B2 JP2013514126A JP2013514126A JP6004586B2 JP 6004586 B2 JP6004586 B2 JP 6004586B2 JP 2013514126 A JP2013514126 A JP 2013514126A JP 2013514126 A JP2013514126 A JP 2013514126A JP 6004586 B2 JP6004586 B2 JP 6004586B2
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- Prior art keywords
- trisaccharide
- fatty acid
- ester
- groups
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
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- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10165707.0 | 2010-06-11 | ||
| EP10165707A EP2397484A1 (en) | 2010-06-11 | 2010-06-11 | Trisaccharide derivates, and their use as adjuvants |
| PCT/NL2011/050393 WO2011155822A1 (en) | 2010-06-11 | 2011-06-03 | Trisaccharide derivates, and their use as adjuvants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016119032A Division JP2016216471A (ja) | 2010-06-11 | 2016-06-15 | 三糖誘導体及びアジュバントとしてのその使用 |
Publications (3)
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| JP2013528211A JP2013528211A (ja) | 2013-07-08 |
| JP2013528211A5 JP2013528211A5 (enExample) | 2014-06-05 |
| JP6004586B2 true JP6004586B2 (ja) | 2016-10-12 |
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| JP2016119032A Pending JP2016216471A (ja) | 2010-06-11 | 2016-06-15 | 三糖誘導体及びアジュバントとしてのその使用 |
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| JP2016119032A Pending JP2016216471A (ja) | 2010-06-11 | 2016-06-15 | 三糖誘導体及びアジュバントとしてのその使用 |
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| EP (3) | EP2397484A1 (enExample) |
| JP (2) | JP6004586B2 (enExample) |
| KR (1) | KR101929973B1 (enExample) |
| CN (1) | CN103154013B (enExample) |
| AU (1) | AU2011262606B2 (enExample) |
| BR (1) | BR112012031440A2 (enExample) |
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| EP2397484A1 (en) * | 2010-06-11 | 2011-12-21 | Immunovo B.V. | Trisaccharide derivates, and their use as adjuvants |
| NZ728551A (en) * | 2014-07-24 | 2023-02-24 | Litevax B V | Sulphated carbohydrate fatty acid esters as vaccine adjuvants |
| KR20250052985A (ko) | 2023-10-11 | 2025-04-21 | 세종대학교산학협력단 | 삼당류의 제조방법 |
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| US4232150A (en) * | 1979-07-09 | 1980-11-04 | American Cyanamid Company | Oligosaccharide precursors to substituted O-α-D and O-β-D-multigalactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6α-D-glucopyranoses |
| GB8703128D0 (en) * | 1987-02-11 | 1987-03-18 | Donmarn Ltd | Anti-scaling compounds |
| US5543505A (en) * | 1993-03-15 | 1996-08-06 | Sloan-Kettering Institute For Cancer Research | Synthetic compounds which bind to H. pylori, and uses thereof |
| US6303120B1 (en) * | 1994-03-15 | 2001-10-16 | Memorial Sloan-Kettering Institute For Cancer Research | Synthesis of glycoconjugates of the lewis y epitope and uses thereof |
| US5708163A (en) * | 1994-03-15 | 1998-01-13 | Sloan-Kettering Institute Of Cancer Research | Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof |
| FI970867A7 (fi) * | 1994-08-04 | 1997-04-08 | Quadrant Drug Delivery Ltd | Kiinteät, annostelusysteemit hallittua vapautumista varten, joihin sys teemeihin molekyylit on sisällytetty ja menetelmät niiden valmistamise ksi |
| BE1008978A5 (fr) | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| US6517860B1 (en) * | 1996-12-31 | 2003-02-11 | Quadrant Holdings Cambridge, Ltd. | Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery |
| US6352722B1 (en) * | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
| JP3041799B1 (ja) * | 1998-09-29 | 2000-05-15 | 株式会社微生物化学研究所 | 新規なアジュバント及びそれを用いたワクチン |
| EP1104767A1 (en) * | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Mono- and disaccharide derivatives containing both fatty acid ester and sulfate ester groups |
| GB0124710D0 (en) * | 2001-10-15 | 2001-12-05 | Quadrant Healthcare Uk Ltd | Therapeutic composition |
| EP1792607B1 (en) * | 2005-12-01 | 2008-10-01 | Wella Aktiengesellschaft | Use of di- or oligosaccharide polyester in hair styling products |
| US9045516B2 (en) * | 2007-04-16 | 2015-06-02 | Suri Saranathan Iyer | Synthetic ligands for the differentiation of closely related toxins and pathogens |
| US9242010B2 (en) * | 2008-05-16 | 2016-01-26 | Research Foundation Of The City University Of New York | Living copolymer-protein/peptide hybrids for biomedical applications |
| WO2010087207A1 (ja) * | 2009-02-02 | 2010-08-05 | 大塚化学株式会社 | 低分子量多硫酸化ヒアルロン酸誘導体及びこれを含有する医薬 |
| EP2397484A1 (en) * | 2010-06-11 | 2011-12-21 | Immunovo B.V. | Trisaccharide derivates, and their use as adjuvants |
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2010
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2011
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- 2011-06-03 RU RU2013100945/04A patent/RU2595717C2/ru active
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2012
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2016
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2017
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