CY1119704T1 - Παραγωγα τρισακχαριτη, και η χρηση τους ως ανοσοενισχυτικα - Google Patents
Παραγωγα τρισακχαριτη, και η χρηση τους ως ανοσοενισχυτικαInfo
- Publication number
- CY1119704T1 CY1119704T1 CY20171101340T CY171101340T CY1119704T1 CY 1119704 T1 CY1119704 T1 CY 1119704T1 CY 20171101340 T CY20171101340 T CY 20171101340T CY 171101340 T CY171101340 T CY 171101340T CY 1119704 T1 CY1119704 T1 CY 1119704T1
- Authority
- CY
- Cyprus
- Prior art keywords
- trisaccharide
- derivatives
- immunosuppressants
- trisaccharides
- adjuvant compositions
- Prior art date
Links
- 150000004043 trisaccharides Chemical class 0.000 title abstract 7
- 229960003444 immunosuppressant agent Drugs 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
- 239000002671 adjuvant Substances 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 125000005313 fatty acid group Chemical group 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dispersion Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10165707A EP2397484A1 (en) | 2010-06-11 | 2010-06-11 | Trisaccharide derivates, and their use as adjuvants |
| EP11725217.1A EP2580226B1 (en) | 2010-06-11 | 2011-06-03 | Trisaccharide derivates, and their use as adjuvants |
| PCT/NL2011/050393 WO2011155822A1 (en) | 2010-06-11 | 2011-06-03 | Trisaccharide derivates, and their use as adjuvants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1119704T1 true CY1119704T1 (el) | 2018-06-27 |
Family
ID=43734127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20171101340T CY1119704T1 (el) | 2010-06-11 | 2017-12-21 | Παραγωγα τρισακχαριτη, και η χρηση τους ως ανοσοενισχυτικα |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US9327020B2 (enExample) |
| EP (3) | EP2397484A1 (enExample) |
| JP (2) | JP6004586B2 (enExample) |
| KR (1) | KR101929973B1 (enExample) |
| CN (1) | CN103154013B (enExample) |
| AU (1) | AU2011262606B2 (enExample) |
| BR (1) | BR112012031440A2 (enExample) |
| CA (1) | CA2802023C (enExample) |
| CY (1) | CY1119704T1 (enExample) |
| DK (1) | DK2580226T3 (enExample) |
| ES (1) | ES2654156T3 (enExample) |
| HR (1) | HRP20171947T1 (enExample) |
| HU (1) | HUE035187T2 (enExample) |
| IL (1) | IL223570A (enExample) |
| LT (1) | LT2580226T (enExample) |
| MX (1) | MX342946B (enExample) |
| NO (1) | NO2580226T3 (enExample) |
| PL (1) | PL2580226T3 (enExample) |
| PT (1) | PT2580226T (enExample) |
| RS (1) | RS56690B1 (enExample) |
| RU (1) | RU2595717C2 (enExample) |
| SI (1) | SI2580226T1 (enExample) |
| SM (1) | SMT201700603T1 (enExample) |
| WO (1) | WO2011155822A1 (enExample) |
| ZA (1) | ZA201209395B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2397484A1 (en) * | 2010-06-11 | 2011-12-21 | Immunovo B.V. | Trisaccharide derivates, and their use as adjuvants |
| NZ728551A (en) * | 2014-07-24 | 2023-02-24 | Litevax B V | Sulphated carbohydrate fatty acid esters as vaccine adjuvants |
| KR20250052985A (ko) | 2023-10-11 | 2025-04-21 | 세종대학교산학협력단 | 삼당류의 제조방법 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4232150A (en) * | 1979-07-09 | 1980-11-04 | American Cyanamid Company | Oligosaccharide precursors to substituted O-α-D and O-β-D-multigalactopyranosyl and glucopyranosyl 1→4 and 1→6 galactopyranosyl 1→6α-D-glucopyranoses |
| GB8703128D0 (en) * | 1987-02-11 | 1987-03-18 | Donmarn Ltd | Anti-scaling compounds |
| US5543505A (en) * | 1993-03-15 | 1996-08-06 | Sloan-Kettering Institute For Cancer Research | Synthetic compounds which bind to H. pylori, and uses thereof |
| US6303120B1 (en) * | 1994-03-15 | 2001-10-16 | Memorial Sloan-Kettering Institute For Cancer Research | Synthesis of glycoconjugates of the lewis y epitope and uses thereof |
| US5708163A (en) * | 1994-03-15 | 1998-01-13 | Sloan-Kettering Institute Of Cancer Research | Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof |
| FI970867A7 (fi) * | 1994-08-04 | 1997-04-08 | Quadrant Drug Delivery Ltd | Kiinteät, annostelusysteemit hallittua vapautumista varten, joihin sys teemeihin molekyylit on sisällytetty ja menetelmät niiden valmistamise ksi |
| BE1008978A5 (fr) | 1994-12-27 | 1996-10-01 | Solvay | Adjuvants pour vaccins. |
| US6517860B1 (en) * | 1996-12-31 | 2003-02-11 | Quadrant Holdings Cambridge, Ltd. | Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery |
| US6352722B1 (en) * | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
| JP3041799B1 (ja) * | 1998-09-29 | 2000-05-15 | 株式会社微生物化学研究所 | 新規なアジュバント及びそれを用いたワクチン |
| EP1104767A1 (en) * | 1999-11-30 | 2001-06-06 | Stichting Dienst Landbouwkundig Onderzoek | Mono- and disaccharide derivatives containing both fatty acid ester and sulfate ester groups |
| GB0124710D0 (en) * | 2001-10-15 | 2001-12-05 | Quadrant Healthcare Uk Ltd | Therapeutic composition |
| EP1792607B1 (en) * | 2005-12-01 | 2008-10-01 | Wella Aktiengesellschaft | Use of di- or oligosaccharide polyester in hair styling products |
| US9045516B2 (en) * | 2007-04-16 | 2015-06-02 | Suri Saranathan Iyer | Synthetic ligands for the differentiation of closely related toxins and pathogens |
| US9242010B2 (en) * | 2008-05-16 | 2016-01-26 | Research Foundation Of The City University Of New York | Living copolymer-protein/peptide hybrids for biomedical applications |
| WO2010087207A1 (ja) * | 2009-02-02 | 2010-08-05 | 大塚化学株式会社 | 低分子量多硫酸化ヒアルロン酸誘導体及びこれを含有する医薬 |
| EP2397484A1 (en) * | 2010-06-11 | 2011-12-21 | Immunovo B.V. | Trisaccharide derivates, and their use as adjuvants |
-
2010
- 2010-06-11 EP EP10165707A patent/EP2397484A1/en not_active Withdrawn
-
2011
- 2011-06-03 HU HUE11725217A patent/HUE035187T2/hu unknown
- 2011-06-03 HR HRP20171947TT patent/HRP20171947T1/hr unknown
- 2011-06-03 LT LTEP11725217.1T patent/LT2580226T/lt unknown
- 2011-06-03 SI SI201131368T patent/SI2580226T1/en unknown
- 2011-06-03 ES ES11725217.1T patent/ES2654156T3/es active Active
- 2011-06-03 CA CA2802023A patent/CA2802023C/en not_active Expired - Fee Related
- 2011-06-03 MX MX2012014422A patent/MX342946B/es active IP Right Grant
- 2011-06-03 PT PT117252171T patent/PT2580226T/pt unknown
- 2011-06-03 SM SM20170603T patent/SMT201700603T1/it unknown
- 2011-06-03 RU RU2013100945/04A patent/RU2595717C2/ru active
- 2011-06-03 WO PCT/NL2011/050393 patent/WO2011155822A1/en not_active Ceased
- 2011-06-03 RS RS20171307A patent/RS56690B1/sr unknown
- 2011-06-03 PL PL11725217T patent/PL2580226T3/pl unknown
- 2011-06-03 EP EP17204140.2A patent/EP3312188A1/en not_active Withdrawn
- 2011-06-03 DK DK11725217.1T patent/DK2580226T3/en active
- 2011-06-03 BR BR112012031440A patent/BR112012031440A2/pt not_active Application Discontinuation
- 2011-06-03 CN CN201180034937.5A patent/CN103154013B/zh not_active Expired - Fee Related
- 2011-06-03 US US13/703,329 patent/US9327020B2/en not_active Expired - Fee Related
- 2011-06-03 AU AU2011262606A patent/AU2011262606B2/en not_active Ceased
- 2011-06-03 NO NO11725217A patent/NO2580226T3/no unknown
- 2011-06-03 EP EP11725217.1A patent/EP2580226B1/en active Active
- 2011-06-03 JP JP2013514126A patent/JP6004586B2/ja not_active Expired - Fee Related
- 2011-06-03 KR KR1020137000623A patent/KR101929973B1/ko not_active Expired - Fee Related
-
2012
- 2012-12-11 ZA ZA2012/09395A patent/ZA201209395B/en unknown
- 2012-12-11 IL IL223570A patent/IL223570A/en active IP Right Grant
-
2016
- 2016-04-05 US US15/090,853 patent/US20170057987A1/en not_active Abandoned
- 2016-06-15 JP JP2016119032A patent/JP2016216471A/ja active Pending
-
2017
- 2017-12-21 CY CY20171101340T patent/CY1119704T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY1123958T1 (el) | Μεθοδος παρασκευης παραγωγων και ενδιαμεσων καρβαμοϋλπυριδονης | |
| CO7400867A2 (es) | Modificador del sabor dulce | |
| BR112012017831A2 (pt) | micro-organismos produtores de ácido eicosapentaenóico, composições e ácido graxo e método de fabricação e uso dos mesmos | |
| EP2633007A4 (en) | RENEWABLE BIO-ESSENCE PRODUCTION | |
| BR112013022397A2 (pt) | vacinas combinadas com doses menores de antígeno e/ou adjuvante | |
| CY1116987T1 (el) | Συμπυκνωμενα ιμιδαζολυλιμιδαζολια ως αντιϊικες ενωσεις | |
| CY1117956T1 (el) | N3-αντικατεστημενα-n1-sulfonyl-5-fluoropyrimidinone παραγωγα | |
| CY1116791T1 (el) | 4-αρυλ-ν-φαινυλ-1,3,5-τριαζιν-αμινες που περιεχουν μια ομαδα σουλφοξιμινης | |
| BR112015015528A8 (pt) | composição e método para produzir um composto | |
| EA201300585A1 (ru) | Иммуномодулирующие олигонуклеотиды | |
| CO6630147A2 (es) | Modificador del sabor dulce | |
| EA201890942A1 (ru) | Мультивалентные вакцины с синтетическими наноносителями | |
| BR112012023950A2 (pt) | formas cristalinas de um macrolídeo, e usos dos mesmos | |
| EP3071229A4 (en) | Use of fluorinated cyclic dinucleotides as oral vaccine adjuvants | |
| BR112014001443A2 (pt) | micro-organismos produtores de ácido eicosapentaenóico, composições de ácidos graxos e métodos de produção e usos dos mesmos | |
| MY156938A (en) | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | |
| EA201791744A3 (ru) | Улучшенная липидная композиция | |
| MX375202B (es) | Composiciones adyuvantes novedosas. | |
| CY1116958T1 (el) | Υποκατεστημενες τριαζολοπυριδινες και η χρηση τους ως ττκ αναστολεις | |
| ECSP13012958A (es) | Inhibidores de benzodioxano de la producción de leucotrieno. | |
| CY1123056T1 (el) | Νεα μορφη χορηγησης της ρασεκαδοτριλης | |
| BR112013020719A2 (pt) | composições de derivados de bimatoprost tipo éster e métodos | |
| MX384120B (es) | Composiciones de vacuna. | |
| MX2013002948A (es) | Composiciones farmaceuticas y nutraceuticas de acido abscisico. | |
| BR112016010862A8 (pt) | formas mórficas de ésteres de hexadeciloxipropil-fosfonato, seu método de preparo e composição compreendendo a dita forma mórfica |