JP5948332B2 - Mll再構成白血病の治療法 - Google Patents

Mll再構成白血病の治療法 Download PDF

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JP5948332B2
JP5948332B2 JP2013528366A JP2013528366A JP5948332B2 JP 5948332 B2 JP5948332 B2 JP 5948332B2 JP 2013528366 A JP2013528366 A JP 2013528366A JP 2013528366 A JP2013528366 A JP 2013528366A JP 5948332 B2 JP5948332 B2 JP 5948332B2
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cell
mll
romidepsin
cells
hdac inhibitor
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JP2013540734A (ja
JP2013540734A5 (https=
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スタム ロナルド
スタム ロナルド
ジェイ.ピー.エム.ストウムペル ドミニクエ
ジェイ.ピー.エム.ストウムペル ドミニクエ
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Celgene Corp
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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JP2013528366A 2010-09-13 2011-09-12 Mll再構成白血病の治療法 Active JP5948332B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38245910P 2010-09-13 2010-09-13
US61/382,459 2010-09-13
PCT/US2011/051173 WO2012037008A2 (en) 2010-09-13 2011-09-12 Therapy for mll-rearranged leukemia

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JP2013540734A JP2013540734A (ja) 2013-11-07
JP2013540734A5 JP2013540734A5 (https=) 2015-01-08
JP5948332B2 true JP5948332B2 (ja) 2016-07-06

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US (1) US8859502B2 (https=)
EP (1) EP2616054A2 (https=)
JP (1) JP5948332B2 (https=)
WO (1) WO2012037008A2 (https=)

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KR102643239B1 (ko) * 2020-03-11 2024-03-05 사회복지법인 삼성생명공익재단 포스포디에스터레이즈 5 억제제를 포함하는, nk-t 세포 림프종 또는 nk 세포 백혈병 예방 또는 치료용 약학적 조성물

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