JP5937060B2 - 呼吸器ウイルス感染症の治療方法 - Google Patents
呼吸器ウイルス感染症の治療方法 Download PDFInfo
- Publication number
- JP5937060B2 JP5937060B2 JP2013503826A JP2013503826A JP5937060B2 JP 5937060 B2 JP5937060 B2 JP 5937060B2 JP 2013503826 A JP2013503826 A JP 2013503826A JP 2013503826 A JP2013503826 A JP 2013503826A JP 5937060 B2 JP5937060 B2 JP 5937060B2
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- alkyl
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- influenza
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- 0 CNC(C(*C(*)=O)=O)N Chemical compound CNC(C(*C(*)=O)=O)N 0.000 description 10
- WKKUULPZZXZQTF-UHFFFAOYSA-N CCOc1cc(C(C)(CS(C)(=O)=O)N(Cc2cccc(NC(C3CC3)=O)c22)C2=O)ccc1OC Chemical compound CCOc1cc(C(C)(CS(C)(=O)=O)N(Cc2cccc(NC(C3CC3)=O)c22)C2=O)ccc1OC WKKUULPZZXZQTF-UHFFFAOYSA-N 0.000 description 1
- NTIBXLBUWCCEBH-UHFFFAOYSA-N COC(CC(c(cc1OC)ccc1OC)N(Cc1ccccc11)C1=O)=O Chemical compound COC(CC(c(cc1OC)ccc1OC)N(Cc1ccccc11)C1=O)=O NTIBXLBUWCCEBH-UHFFFAOYSA-N 0.000 description 1
- UVSMNLNDYGZFPF-UHFFFAOYSA-N Nc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O Chemical compound Nc1cccc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O UVSMNLNDYGZFPF-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32180210P | 2010-04-07 | 2010-04-07 | |
| US61/321,802 | 2010-04-07 | ||
| US201161435726P | 2011-01-24 | 2011-01-24 | |
| US61/435,726 | 2011-01-24 | ||
| PCT/US2011/031190 WO2011127019A2 (en) | 2010-04-07 | 2011-04-05 | Methods for treating respiratory viral infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013523817A JP2013523817A (ja) | 2013-06-17 |
| JP2013523817A5 JP2013523817A5 (https=) | 2014-05-22 |
| JP5937060B2 true JP5937060B2 (ja) | 2016-06-22 |
Family
ID=44168807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013503826A Active JP5937060B2 (ja) | 2010-04-07 | 2011-04-05 | 呼吸器ウイルス感染症の治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9408831B2 (https=) |
| EP (1) | EP2555769B1 (https=) |
| JP (1) | JP5937060B2 (https=) |
| CA (1) | CA2794096A1 (https=) |
| MX (1) | MX341050B (https=) |
| WO (1) | WO2011127019A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105873611A (zh) * | 2013-11-06 | 2016-08-17 | 细胞基因公司 | 利用pde4调节剂治疗病毒性疾病的组合物和方法 |
| GB201504763D0 (en) | 2015-03-20 | 2015-05-06 | Mironid Ltd | Compounds and uses |
| US10011611B2 (en) | 2015-08-14 | 2018-07-03 | Reaction Biology Corp. | Histone deacetylase inhibitors and methods for use thereof |
| GB201616439D0 (en) | 2016-09-28 | 2016-11-09 | Mironid Limited | Compounds and uses |
| GB201805527D0 (en) | 2018-04-04 | 2018-05-16 | Mironid Ltd | Compounds and their use as pde4 activators |
| WO2020223608A1 (en) * | 2019-05-02 | 2020-11-05 | Thiolab, Llc, | Inhibition of il-1 and il-6 inflammation |
| EP4132503B1 (en) * | 2020-04-10 | 2026-04-22 | University of Georgia Research Foundation, Inc. | Probenecid for use in the treatment of sars-co-v2 infections |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
| WO2022011305A2 (en) * | 2020-07-09 | 2022-01-13 | Beyond Barriers Therapeutics, Inc. | Intranasal administration of an antioxidant compound for treating coronavirus infection |
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| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| US4328245A (en) | 1981-02-13 | 1982-05-04 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4410545A (en) | 1981-02-13 | 1983-10-18 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4409239A (en) | 1982-01-21 | 1983-10-11 | Syntex (U.S.A.) Inc. | Propylene glycol diester solutions of PGE-type compounds |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US5463063A (en) | 1993-07-02 | 1995-10-31 | Celgene Corporation | Ring closure of N-phthaloylglutamines |
| US5698579A (en) | 1993-07-02 | 1997-12-16 | Celgene Corporation | Cyclic amides |
| US5605914A (en) | 1993-07-02 | 1997-02-25 | Celgene Corporation | Imides |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
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| US5703098A (en) | 1994-12-30 | 1997-12-30 | Celgene Corporation | Immunotherapeutic imides/amides |
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| DE122007000079I2 (de) | 1996-07-24 | 2010-08-12 | Celgene Corp | Substituierte 2-(2,6-dioxopiperidin-3-yl)-phthalimide und -1-oxoisoindoline und verfahren zur reduzierung des tnf-alpha-spiegels |
| US5635517B1 (en) | 1996-07-24 | 1999-06-29 | Celgene Corp | Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines |
| US6281230B1 (en) | 1996-07-24 | 2001-08-28 | Celgene Corporation | Isoindolines, method of use, and pharmaceutical compositions |
| HU228769B1 (en) | 1996-07-24 | 2013-05-28 | Celgene Corp | Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1-oxoisoindolines and their use for production of pharmaceutical compositions for mammals to reduce the level of tnf-alpha |
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| KR20070092276A (ko) | 2004-12-13 | 2007-09-12 | 셀진 코포레이션 | Pde4 조절인자를 포함하는 조성물 및 이의 기도염의치료 또는 예방을 위한 용도 |
| JP2010530870A (ja) * | 2007-06-22 | 2010-09-16 | エーテーツェー チューリッヒ | 抗ウイルス剤 |
| US20110028510A1 (en) * | 2009-02-18 | 2011-02-03 | Combinatorx (Singapore) Pte. Ltd. | Compositions, Methods, and Kits for Treating Influenza Viral Infections |
| US9713375B1 (en) | 2015-02-26 | 2017-07-25 | Brett Einar Rahm | Collapsible portable table |
-
2011
- 2011-04-05 MX MX2012011547A patent/MX341050B/es active IP Right Grant
- 2011-04-05 JP JP2013503826A patent/JP5937060B2/ja active Active
- 2011-04-05 WO PCT/US2011/031190 patent/WO2011127019A2/en not_active Ceased
- 2011-04-05 US US13/639,848 patent/US9408831B2/en active Active
- 2011-04-05 CA CA2794096A patent/CA2794096A1/en not_active Abandoned
- 2011-04-05 EP EP11714208.3A patent/EP2555769B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2794096A1 (en) | 2011-10-13 |
| EP2555769A2 (en) | 2013-02-13 |
| US9408831B2 (en) | 2016-08-09 |
| WO2011127019A3 (en) | 2011-12-01 |
| WO2011127019A2 (en) | 2011-10-13 |
| JP2013523817A (ja) | 2013-06-17 |
| US20130136770A1 (en) | 2013-05-30 |
| EP2555769B1 (en) | 2022-01-12 |
| MX2012011547A (es) | 2012-11-16 |
| MX341050B (es) | 2016-08-05 |
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