JP5907874B2 - 駆動アセンブリを操作するためのボタン部材 - Google Patents
駆動アセンブリを操作するためのボタン部材 Download PDFInfo
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- JP5907874B2 JP5907874B2 JP2012531379A JP2012531379A JP5907874B2 JP 5907874 B2 JP5907874 B2 JP 5907874B2 JP 2012531379 A JP2012531379 A JP 2012531379A JP 2012531379 A JP2012531379 A JP 2012531379A JP 5907874 B2 JP5907874 B2 JP 5907874B2
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- drug delivery
- delivery device
- button
- drive assembly
- button member
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3156—Mechanically operated dose setting member using volume steps only adjustable in discrete intervals, i.e. individually distinct intervals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2492—Ampoule holder connected to rest of syringe via snap connection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/60—General characteristics of the apparatus with identification means
- A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
Description
ここで一実施態様において、薬学的に活性な化合物は、最大で1500Daまでの分子量を有し、及び/又は、ペプチド、蛋白質、多糖類、ワクチン、DNA、RNA、抗体、酵素、抗体、ホルモン、若しくはオリゴヌクレオチド、又は上記の薬学的に活性な化合物の混合物であり、
ここで更なる実施態様において、薬学的に活性な化合物は、糖尿病、又は糖尿病性網膜症などの糖尿病関連の合併症、深部静脈又は肺血栓塞栓症などの血栓塞栓症、急性冠症候群(ACS)、狭心症、心筋梗塞、癌、黄斑変性症、炎症、枯草熱、アテローム性動脈硬化症、及び/又は、関節リウマチ性の治療、及び/又は、予防に有用であり、
ここで更なる実施態様において、薬学的に活性な化合物は、糖尿病、又は糖尿病性網膜症などの糖尿病に関連する合併症の治療、及び/又は、予防のための、少なくとも1つのペプチドを含み、
ここで更なる実施態様において、薬学的に活性な化合物は、少なくとも1つのヒトインスリン、又はヒトインスリン類似体若しくは誘導体、グルカゴン様ペプチド(GLP−1)、又はその類似体若しくは誘導体、又はエキセンジン−3又はエキセンジン−4、若しくはエキセンジン−3又はエキセンジン−4の類似体若しくは誘導体を含む。
H−(Lys)4−desPro36,desPro37エキセンジン−4(1−39)−NH2;
H−(Lys)5−desPro36,desPro37エキセンジン−4(1−39)−NH2;
desPro36[Asp28]エキセンジン−4(1−39);
desPro36[IsoAsp28]エキセンジン−4(1−39);
desPro36[Met(O)14,Asp28]エキセンジン−4(1−39);
desPro36[Met(O)14,IsoAsp28]エキセンジン−4(1−39);
desPro36[Trp(O2)25,Asp28]エキセンジン−4(1−39);
desPro36[Trp(O2)25,IsoAsp28]エキセンジン−4(1−39);
desPro36[Met(O)14Trp(O2)25,Asp28]エキセンジン−4(1−39);
desPro36[Met(O)14Trp(O2)25,IsoAsp28]エキセンジン−4(1−39);又は
desPro36[Asp28]エキセンジン−4(1−39);
desPro36[IsoAsp28]エキセンジン−4(1−39);
desPro36[Met(O)14,Asp28]エキセンジン−4(1−39);
desPro36[Met(O)14,IsoAsp28]エキセンジン−(1−39);
desPro36[Trp(O2)25,Asp28]エキセンジン−4(1−39);
desPro36[Trp(O2)25,IsoAsp28]エキセンジン−4(1−39);
desPro36[Met(O)14,Trp(O2)25,Asp28]エキセンジン−4(1−39);
desPro36[Met(O)14,Trp(O2)25,IsoAsp28]エキセンジン−4(1−39);
ここで、基−Lys6−NH2は、エキセンジン−4誘導体のC−末端と連結してもよく;
H−(Lys)6−desPro36[Asp28]エキセンジン−4(1−39)−Lys6−NH2;
desAsp28,Pro36,Pro37,Pro38エキセンジン−4(1−39)−NH2;
H−(Lys)6−desPro36,Pro38[Asp28]エキセンジン−4(1−39)−NH2;
H−Asn−(Glu)5desPro36,Pro37,Pro38[Asp28]エキセンジン−4(1−39)−NH2;
desPro36,Pro37,Pro38[Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−(Lys)6−desPro36,Pro37,Pro38[Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−Asn−(Glu)5−desPro36,Pro37,Pro38[Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−(Lys)6−desPro36[Trp(O2)25,Asp28]エキセンジン−4(1−39)−Lys6−NH2;
H−desAsp28 Pro36,Pro37,Pro38[Trp(O2)25]エキセンジン−4(1−39)−NH2;
H−(Lys)6−desPro36,Pro37,Pro38[Trp(O2)25,Asp28]エキセンジン−4(1−39)−NH2;
H−Asn−(Glu)5−desPro36,Pro37,Pro38[Trp(O2)25,Asp28]エキセンジン−4(1−39)−NH2;
desPro36,Pro37,Pro38[Trp(O2)25,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−(Lys)6−des Pro36,Pro37,Pro38[Trp(O2)25,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−Asn−(Glu)5−desPro36,Pro37,Pro38[Trp(O2)25,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−(Lys)6−desPro36[Met(O)14,Asp28]エキセンジン−4(1−39)−Lys6−NH2;
desMet(O)14,Asp28,Pro36,Pro37,Pro38 エキセンジン−4(1−39)−NH2;
H−(Lys)6−desPro36,Pro37,Pro38[Met(O)14,Asp28]エキセンジン−4(1−39)−NH2;
H−Asn−(Glu)5−desPro36,Pro37,Pro38[Met(O)14,Asp28]エキセンジン−4(1−39)−NH2;
desPro36,Pro37,Pro38[Met(O)14,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−(Lys)6−desPro36,Pro37,Pro38[Met(O)14,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−Asn−(Glu)5,desPro36,Pro37,Pro38[Met(O)14,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−Lys6−desPro36[Met(O)14,Trp(O2)25, Asp28]エキセンジン−4(1−39)−Lys6−NH2;
H−desAsp28,Pro36,Pro37,Pro38[Met(O)14,Trp(O2)25]エキセンジン−4(1−39)−NH2;
H−(Lys)6−des Pro36,Pro37,Pro38[Met(O)14,Asp28]エキセンジン−4(1−39)−NH2;
H−Asn−(Glu)5−desPro36,Pro37,Pro38[Met(O)14,Trp(O2)25,Asp28]エキセンジン−4(1−39)−NH2;
desPro36,Pro37,Pro38[Met(O)14,Trp(O2)25,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
H−(Lys)6−desPro36,Pro37,Pro38[Met(O)14,Trp(O2)25,Asp28]エキセンジン−4(S1−39)−(Lys)6−NH2;
H−Asn−(Glu)5−desPro36,Pro37,Pro38[Met(O)14,Trp(O2)25,Asp28]エキセンジン−4(1−39)−(Lys)6−NH2;
又は前述のいずれかのエキセンジン−4誘導体の薬学的に許容可能な塩若しくは溶媒和物;
から選択される。
Publishing社,Easton, Pa., U.S.A.,1985 及び Encyclopedia of Pharmaceutical Technologyに記載されている。
1:アセンブリ;
4:駆動アセンブリ;
5:ボタン、ボタン部材;
5b:ボタン;
5d:ボタン;
9:カートリッジアセンブリ、流体リザーバ;
8:栓;
7:カートリッジホルダ;
10:本体;
10a:チャンネル、ガイディング凹部トラック;
11:遠位端、遠位方向;
12:近位端、近位方向;
32、34:型式の部分;
41:ピストンロッド;
41a、41b:親ねじ;
41c:親ねじ;
42;可動ピボット;
42a、42b:駆動スリーブ;
43: 逆止めラチェット;
44:レバー;
46:固定ピボット;
46a:親ねじナット;
46b:親ねじナット;
47:親板;
49:駆動スリーブ;
51:チャンネル;
52:螺旋ガイディングトラック、チャンネル
53:クリップ、逆止めラチェット;
54:戻り止め;
55:螺旋ガイディングトラック;
100:窓;
101:窓;
420b:近位端;
421、494:凹部;
422、493:突起;
423、492:傾斜面;
424a:螺旋状に配置された突起;
425b:突起;
426b:突起;
428、429:端部境界エレメント;
460: 突起;
461:ラグ、突起;
422:保持エレメント;
462b:保持エレメント;
490:マーカー、矢印;
495:螺旋状表面;
500:本体仕上げ機;
501:ボタン仕上げ機;
503:螺旋状突起;
508:スプライン;
505:カラー;
506:突起、ラグ;
507:マーカー:
511:チャンネルの第一の部分;
512:チャンネルの第二の部分;
550:ネジ山;
551:螺旋形状表面;
555:突起;
Claims (9)
- 薬物送達デバイスであって:
本体(10);
実質的に本体(10)内に配置された駆動アセンブリ(4);および
薬物送達デバイスの駆動アセンブリ(4)を操作するための、かつ本体(10)の近位端に配置された、ボタン部材(5);
を含んでなり、該ボタン部材(5)は:
−使用者によりアクセス可能でありかつ使用者により動かせるよう構成されている第一の部分;
−駆動アセンブリ(4)と有効な連結にある第二の部分;
を、含んでなり:
−該第二の部分は、第一の方向への第一のトラック部分(511)及び第二の方向への第二のトラック部分(512)を有する第一のガイディングトラック(51)を含んでなり:ここで、
−第一のトラック部分(511)は、ボタン部材(5)が駆動アセンブリ(4)に作用し、プライミングを含む用量の設定及び投与を容易にするための駆動アセンブリ(4)の調整を行うよう、ボタン部材(5)の動きを本体(10)に対する実質的な回転運動に制限するように適合され;
−第二のトラック部分(512)は、ボタン部材(5)が駆動アセンブリ(4)に作用し、医薬品の用量を設定及び投与するよう、ボタン部材(5)の動きを本体(10)に対する軸方向運動に限定するように適合され;
ここで、ボタン部材(5)は、ボタン部材(5)の軸方向運動中、駆動アセンブリ(4)に対して変位し、軸方向運動は用量の設定及び投与の間に起こり、そしてボタン部材(5)の軸方向運動が可逆的である、
薬物送達デバイス。 - 第一の方向は、第二の方向と実質的に垂直である、請求項1に記載の薬物送達デバイス。
- 第一のガイディングトラック(51)は、ラグ、エッジ、凹部、又はチャンネルを含んでなる、請求項1又は2に記載の薬物送達デバイス。
- 第二のガイディングトラック(52)を更に含み、該第二のガイディングトラック(52)は、医薬品の設定及び投与に備えて薬物送達デバイスを調整するためにボタン部材(5)の実質的な回転運動中に、駆動アセンブリ(4)に作用する、請求項1〜3のいずれか1項に記載の薬物送達デバイス。
- 第二のガイディングトラック(52)は、ラグ、エッジ、凹部又はチャンネルを含んでなる、請求項4に記載の薬物送達デバイス。
- 第二のガイディングトラック(52)は、螺旋形状を含んでなる、請求項4又は5に記載の薬物送達デバイス。
- 第二のガイディングトラック(52)は、保持エレメント(53)を含んでなり、該エレメント(53)は、ボタン部材(5)が軸方向に可動であるとき、ボタン部材(5)が可逆的に捻じれ、又は回転することを阻止する、請求項4〜6のいずれか1項に記載の薬物送達デバイス。
- 保持エレメント(53)は、ラチェットを含んでなり、該ラチェットは、駆動アセンブリ(4)と操作係合にある、請求項7に記載の薬物送達デバイス。
- 第一のトラック部分は、ボタン部材(5)を解放可能に保持するための戻り止めを含んでなる、請求項1〜8のいずれか1項に記載の薬物送達デバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09171744 | 2009-09-30 | ||
EP09171744.7 | 2009-09-30 | ||
PCT/EP2010/064402 WO2011039211A1 (en) | 2009-09-30 | 2010-09-29 | Button member for operating a drive assembly |
Publications (2)
Publication Number | Publication Date |
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JP2013506450A JP2013506450A (ja) | 2013-02-28 |
JP5907874B2 true JP5907874B2 (ja) | 2016-04-26 |
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JP2012531379A Expired - Fee Related JP5907874B2 (ja) | 2009-09-30 | 2010-09-29 | 駆動アセンブリを操作するためのボタン部材 |
Country Status (6)
Country | Link |
---|---|
US (1) | US20120283654A1 (ja) |
EP (1) | EP2482890B1 (ja) |
JP (1) | JP5907874B2 (ja) |
CA (1) | CA2773015A1 (ja) |
DK (1) | DK2482890T3 (ja) |
WO (1) | WO2011039211A1 (ja) |
Cited By (2)
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---|---|---|---|---|
US11433186B2 (en) | 2017-12-13 | 2022-09-06 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
US11439758B2 (en) | 2019-06-05 | 2022-09-13 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0307589A (pt) | 2002-02-11 | 2005-02-01 | Antares Pharma Inc | Dispositivo de injeção intradérmica |
ES2716135T5 (es) | 2005-01-24 | 2023-06-15 | Antares Pharma Inc | Inyector de chorro asistido por aguja con jeringa precargada |
US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
WO2009114542A1 (en) | 2008-03-10 | 2009-09-17 | Antares Pharma, Inc. | Injector safety device |
CA2732812C (en) | 2008-08-05 | 2017-10-31 | Antares Pharma, Inc. | Multiple dosage injector |
US8579865B2 (en) | 2009-03-20 | 2013-11-12 | Antares Pharma, Inc. | Hazardous agent injection system |
EP2292286A1 (en) * | 2009-09-07 | 2011-03-09 | Sanofi-Aventis Deutschland GmbH | Drive mechanism for a medication delivery device and medication delivery device |
WO2011026931A1 (en) * | 2009-09-07 | 2011-03-10 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for drug delivery device |
AR078457A1 (es) * | 2009-09-30 | 2011-11-09 | Sanofi Aventis Deutschland | Mecanismo accionador para un dispositivo de descarga de farmacos |
CA2773670A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device and use of a reset member for a drive mechanism |
JP5752693B2 (ja) * | 2009-09-30 | 2015-07-22 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイス用のアセンブリ及びピストンロッド |
US9533107B2 (en) * | 2009-09-30 | 2017-01-03 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with biasing track for transmitting load to rotatable drive member enabling subsequent dose dispense |
DK2482889T3 (en) * | 2009-09-30 | 2016-05-17 | Sanofi Aventis Deutschland | ACCOMMODATION drug delivery device |
US9731075B2 (en) * | 2011-06-17 | 2017-08-15 | Sanofi-Aventis Deutschland Gmbh | Cartridge holder latch mating to axial through opening of bearing with central threaded opening |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
PT2822618T (pt) | 2012-03-06 | 2024-03-04 | Antares Pharma Inc | Seringa pré-cheia com característica de força de rutura |
EP2833944A4 (en) | 2012-04-06 | 2016-05-25 | Antares Pharma Inc | ADMINISTRATION OF TESTOSTERONE COMPOSITIONS BY NEEDLE-SUPPORTED NOZZLE INJECTION |
RU2724011C1 (ru) | 2012-04-13 | 2020-06-18 | Бектон, Дикинсон Энд Компани | Автоматизированное устройство для инъекций |
US9364610B2 (en) | 2012-05-07 | 2016-06-14 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
CA2900672C (en) | 2013-02-11 | 2018-03-27 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
ES2742046T3 (es) | 2013-03-11 | 2020-02-12 | Antares Pharma Inc | Inyector de dosis con sistema de piñón |
WO2014165136A1 (en) | 2013-03-12 | 2014-10-09 | Antares Pharma, Inc. | Constant volume prefilled syringes and kits thereof |
CN104307072A (zh) * | 2014-10-29 | 2015-01-28 | 杭州普昂医疗科技有限公司 | 安全式胰岛素笔针 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1078911A (fr) * | 1949-08-17 | 1954-11-24 | Seringue hypodermique automatique et son ampoule | |
FR1156298A (fr) * | 1956-09-06 | 1958-05-14 | Seringues Ind Soc D Expl Des | Seringue pour injections hypodermiques |
US4475905A (en) * | 1982-09-30 | 1984-10-09 | Himmelstrup Anders B | Injection device |
US5346480A (en) * | 1992-12-14 | 1994-09-13 | Q-Med, Inc. | Syringe with retractable needle |
GB9300567D0 (en) * | 1993-01-12 | 1993-03-03 | Owen Mumford Ltd | Improvements relating to devices for generating intermittent motion |
US5634910A (en) * | 1995-09-22 | 1997-06-03 | Ryder International Corporation | Syringe instrument |
US6348043B1 (en) * | 1998-12-29 | 2002-02-19 | Mckinley Medical, Lllp | Multi-dose infusion pump providing minimal flow between doses |
SE9901366D0 (sv) * | 1999-04-16 | 1999-04-16 | Pharmacia & Upjohn Ab | Injector device and method for its operation |
CA2541483C (en) * | 2003-10-16 | 2011-12-06 | Eli Lilly And Company | Fixed dose medication dispensing device |
JP4131001B2 (ja) * | 2006-07-28 | 2008-08-13 | 大成化工株式会社 | 定量吐出装置 |
GB2441129B (en) * | 2006-08-26 | 2008-11-26 | Norwich Pharma Technologies Ltd | Dosage Dispensing Canister |
MX2009009494A (es) * | 2007-03-09 | 2009-09-15 | Lilly Co Eli | Mecanismo de retardo para dispositivo de inyeccion automatica. |
DE102007019124A1 (de) * | 2007-04-23 | 2008-11-06 | Tecpharma Licensing Ag | Rückdrehbare Dosiervorrichtung für eine Injektionsvorrichtung |
-
2010
- 2010-09-29 EP EP10759641.3A patent/EP2482890B1/en not_active Not-in-force
- 2010-09-29 JP JP2012531379A patent/JP5907874B2/ja not_active Expired - Fee Related
- 2010-09-29 US US13/395,730 patent/US20120283654A1/en not_active Abandoned
- 2010-09-29 CA CA2773015A patent/CA2773015A1/en not_active Abandoned
- 2010-09-29 WO PCT/EP2010/064402 patent/WO2011039211A1/en active Application Filing
- 2010-09-29 DK DK10759641.3T patent/DK2482890T3/en active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11433186B2 (en) | 2017-12-13 | 2022-09-06 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
US11439758B2 (en) | 2019-06-05 | 2022-09-13 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
Also Published As
Publication number | Publication date |
---|---|
US20120283654A1 (en) | 2012-11-08 |
CA2773015A1 (en) | 2011-04-07 |
EP2482890B1 (en) | 2014-12-03 |
EP2482890A1 (en) | 2012-08-08 |
DK2482890T3 (en) | 2015-03-02 |
WO2011039211A1 (en) | 2011-04-07 |
JP2013506450A (ja) | 2013-02-28 |
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