JP5907310B2 - オキサジナン化合物の結晶形及びその製造方法 - Google Patents

オキサジナン化合物の結晶形及びその製造方法 Download PDF

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JP5907310B2
JP5907310B2 JP2015512427A JP2015512427A JP5907310B2 JP 5907310 B2 JP5907310 B2 JP 5907310B2 JP 2015512427 A JP2015512427 A JP 2015512427A JP 2015512427 A JP2015512427 A JP 2015512427A JP 5907310 B2 JP5907310 B2 JP 5907310B2
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compound
methyl
degrees
triazol
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JPWO2015087853A1 (ja
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彩 二村
彩 二村
信隆 服部
信隆 服部
洋樹 浦部
洋樹 浦部
有也 尾形
有也 尾形
尚人 大崎
尚人 大崎
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Taisho Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Neurosurgery (AREA)
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  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2015512427A 2013-12-13 2014-12-09 オキサジナン化合物の結晶形及びその製造方法 Active JP5907310B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013257691 2013-12-13
JP2013257691 2013-12-13
PCT/JP2014/082497 WO2015087853A1 (fr) 2013-12-13 2014-12-09 Forme cristalline de composé oxazinane et son procédé de préparation

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JP5907310B2 true JP5907310B2 (ja) 2016-04-26
JPWO2015087853A1 JPWO2015087853A1 (ja) 2017-03-16

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JP (1) JP5907310B2 (fr)
CN (1) CN105814042B (fr)
WO (1) WO2015087853A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110869368B (zh) * 2017-07-13 2023-03-28 大正制药株式会社 （2s）-2-［（1h-吡唑-1-基）甲基］-1,3-噁嗪烷衍生物的制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004533440A (ja) * 2001-05-05 2004-11-04 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー Ｎ−アロイルサイクリックアミン
JP2004534026A (ja) * 2001-05-05 2004-11-11 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー オレキシン受容体アンタゴニストとしてのｎ−アロイルサイクリックアミン誘導体
JP2005501026A (ja) * 2001-06-28 2005-01-13 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー 化合物
JP2012506376A (ja) * 2008-10-21 2012-03-15 メルク・シャープ・エンド・ドーム・コーポレイション ２，５−二置換モルホリンオレキシン受容体アンタゴニスト
WO2013068935A1 (fr) * 2011-11-08 2013-05-16 Actelion Pharmaceuticals Ltd Dérivés de 2-(1,2,3-triazol-2-yl)benzamide et de 3-(1,2,3-triazol-2-yl)picolinamide en tant qu'antagonistes des récepteurs d'oréxine
WO2013187467A1 (fr) * 2012-06-15 2013-12-19 大正製薬株式会社 Dérivé d'amine cyclique méthylé hétéroaromatique
JP2015131803A (ja) * 2013-12-13 2015-07-23 大正製薬株式会社 ヘテロ芳香環メチル環状アミン誘導体を含有する医薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8410142B2 (en) * 2007-03-02 2013-04-02 Merck Sharp & Dohme Corp. Bipyridine carboxamide orexin receptor antagonists
KR20100117061A (ko) * 2007-12-20 2010-11-02 테크니쉐 유니버시테이트 아인트호벤 전도성 트랙의 제조방법
JP2012505263A (ja) * 2008-10-14 2012-03-01 アクテリオン ファーマシューティカルズ リミテッド フェネチルアミド誘導体及びそれらのヘテロシクリル類似体
JP5635991B2 (ja) * 2008-10-30 2014-12-03 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． イソニコチンアミドオレキシン受容体アンタゴニスト

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004533440A (ja) * 2001-05-05 2004-11-04 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー Ｎ−アロイルサイクリックアミン
JP2004534026A (ja) * 2001-05-05 2004-11-11 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー オレキシン受容体アンタゴニストとしてのｎ−アロイルサイクリックアミン誘導体
JP2005501026A (ja) * 2001-06-28 2005-01-13 スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー 化合物
JP2012506376A (ja) * 2008-10-21 2012-03-15 メルク・シャープ・エンド・ドーム・コーポレイション ２，５−二置換モルホリンオレキシン受容体アンタゴニスト
WO2013068935A1 (fr) * 2011-11-08 2013-05-16 Actelion Pharmaceuticals Ltd Dérivés de 2-(1,2,3-triazol-2-yl)benzamide et de 3-(1,2,3-triazol-2-yl)picolinamide en tant qu'antagonistes des récepteurs d'oréxine
WO2013187467A1 (fr) * 2012-06-15 2013-12-19 大正製薬株式会社 Dérivé d'amine cyclique méthylé hétéroaromatique
JP2015131803A (ja) * 2013-12-13 2015-07-23 大正製薬株式会社 ヘテロ芳香環メチル環状アミン誘導体を含有する医薬

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CN105814042B (zh) 2018-09-28
WO2015087853A1 (fr) 2015-06-18
JPWO2015087853A1 (ja) 2017-03-16
CN105814042A (zh) 2016-07-27

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