JP5888753B2 - 効率的な人工多能性幹細胞の樹立方法 - Google Patents

効率的な人工多能性幹細胞の樹立方法 Download PDF

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JP5888753B2
JP5888753B2 JP2013512280A JP2013512280A JP5888753B2 JP 5888753 B2 JP5888753 B2 JP 5888753B2 JP 2013512280 A JP2013512280 A JP 2013512280A JP 2013512280 A JP2013512280 A JP 2013512280A JP 5888753 B2 JP5888753 B2 JP 5888753B2
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cells
cyclin
cell
oct3
sox2
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JP2013544069A (ja
JP2013544069A5 (OSRAM
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伸弥 山中
伸弥 山中
和利 高橋
和利 高橋
剛士 田邊
剛士 田邊
ヒョンジョン ホン
ヒョンジョン ホン
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Kyoto University NUC
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    • C12N9/14—Hydrolases (3)
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JP2013512280A 2010-11-04 2011-11-04 効率的な人工多能性幹細胞の樹立方法 Active JP5888753B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41017810P 2010-11-04 2010-11-04
US61/410,178 2010-11-04
PCT/JP2011/076017 WO2012060473A1 (en) 2010-11-04 2011-11-04 Method of efficiently establishing induced pluripotent stem cells

Publications (3)

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JP2013544069A JP2013544069A (ja) 2013-12-12
JP2013544069A5 JP2013544069A5 (OSRAM) 2014-12-18
JP5888753B2 true JP5888753B2 (ja) 2016-03-22

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US (1) US9637732B2 (OSRAM)
EP (1) EP2635678A4 (OSRAM)
JP (1) JP5888753B2 (OSRAM)
WO (1) WO2012060473A1 (OSRAM)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
BR112014013664A2 (pt) 2011-12-05 2020-11-03 Factor Bioscience Inc. métodos e produtos para transfectar células
US8497124B2 (en) 2011-12-05 2013-07-30 Factor Bioscience Inc. Methods and products for reprogramming cells to a less differentiated state
BR122019025681B1 (pt) 2012-11-01 2023-04-18 Factor Bioscience Inc Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula
US9770489B2 (en) 2014-01-31 2017-09-26 Factor Bioscience Inc. Methods and products for nucleic acid production and delivery
US11241505B2 (en) 2015-02-13 2022-02-08 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
IL263224B2 (en) 2016-05-25 2024-03-01 Inst Nat Sante Rech Med Use of a histone deacetylase inhibitor and a population of inactivated pluripotent cells for treating cancer
US10576167B2 (en) 2016-08-17 2020-03-03 Factor Bioscience Inc. Nucleic acid products and methods of administration thereof
CA3083158A1 (en) 2017-11-24 2019-05-31 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods and compositions for treating cancers
US20210236633A1 (en) 2018-08-06 2021-08-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and compositions for treating cancers
JP2022535192A (ja) 2019-05-14 2022-08-05 アレフ ファームス リミテッド 多能性細胞凝集体およびそれらの使用
KR20220039719A (ko) 2019-07-03 2022-03-29 팩터 바이오사이언스 인크. 양이온성 지질 및 이의 용도
US10501404B1 (en) 2019-07-30 2019-12-10 Factor Bioscience Inc. Cationic lipids and transfection methods
US12492372B2 (en) 2020-11-24 2025-12-09 Monash University Induced stem cells
WO2022109667A1 (en) 2020-11-24 2022-06-02 Monash University Methods and cellular structures
WO2022207889A1 (en) 2021-04-01 2022-10-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Liver organoid manufacturing methods, liver organoids obtained with the same, and uses thereof

Family Cites Families (9)

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AUPQ307399A0 (en) * 1999-09-24 1999-10-21 Luminis Pty Limited Cell cycle control
US9567591B2 (en) * 2003-05-15 2017-02-14 Mello Biotechnology, Inc. Generation of human embryonic stem-like cells using intronic RNA
EP4223769A3 (en) 2005-12-13 2023-11-01 Kyoto University Nuclear reprogramming factor
EP3878949B1 (en) 2007-04-07 2025-06-04 Whitehead Institute for Biomedical Research Reprogramming of somatic cells
AU2008297024B2 (en) 2007-10-31 2014-08-28 Kyoto University Nuclear reprogramming method
JP5945385B2 (ja) 2008-01-16 2016-07-05 リン、シー−ランLIN, Shi−Lung 誘導性組換えｒｎａ因子を用いた腫瘍のない多能性胚性幹様細胞の生成
WO2009157201A1 (en) 2008-06-26 2009-12-30 Osaka University Method and kit for preparing ips cells
JP5340265B2 (ja) 2008-06-27 2013-11-13 国立大学法人京都大学 効率的な人工多能性幹細胞の樹立方法
EP2295538B1 (en) * 2008-07-07 2015-10-21 Takara Bio Inc. Method for production of pluripotent stem cell

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Publication number Publication date
JP2013544069A (ja) 2013-12-12
US9637732B2 (en) 2017-05-02
US20130183757A1 (en) 2013-07-18
EP2635678A4 (en) 2014-04-23
EP2635678A1 (en) 2013-09-11
WO2012060473A1 (en) 2012-05-10

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