JP2013544069A5 - - Google Patents
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- Publication number
- JP2013544069A5 JP2013544069A5 JP2013512280A JP2013512280A JP2013544069A5 JP 2013544069 A5 JP2013544069 A5 JP 2013544069A5 JP 2013512280 A JP2013512280 A JP 2013512280A JP 2013512280 A JP2013512280 A JP 2013512280A JP 2013544069 A5 JP2013544069 A5 JP 2013544069A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclin
- family
- nuclear reprogramming
- proteins
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 11
- 210000004027 cell Anatomy 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 108090000623 proteins and genes Proteins 0.000 claims 8
- 230000008672 reprogramming Effects 0.000 claims 7
- 210000001082 somatic cell Anatomy 0.000 claims 7
- 239000000126 substance Substances 0.000 claims 6
- 102000003910 Cyclin D Human genes 0.000 claims 5
- 108090000259 Cyclin D Proteins 0.000 claims 5
- 108010058546 Cyclin D1 Proteins 0.000 claims 4
- 108010058545 Cyclin D3 Proteins 0.000 claims 4
- 102100024165 G1/S-specific cyclin-D1 Human genes 0.000 claims 4
- 102100037859 G1/S-specific cyclin-D3 Human genes 0.000 claims 4
- 108700021430 Kruppel-Like Factor 4 Proteins 0.000 claims 4
- 108010058544 Cyclin D2 Proteins 0.000 claims 3
- 102100024185 G1/S-specific cyclin-D2 Human genes 0.000 claims 3
- 101100247004 Rattus norvegicus Qsox1 gene Proteins 0.000 claims 3
- 101150086694 SLC22A3 gene Proteins 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 230000004069 differentiation Effects 0.000 claims 2
- 238000011419 induction treatment Methods 0.000 claims 2
- 108091057508 Myc family Proteins 0.000 claims 1
- 101710135898 Myc proto-oncogene protein Proteins 0.000 claims 1
- 102100038895 Myc proto-oncogene protein Human genes 0.000 claims 1
- 101710150448 Transcriptional regulator Myc Proteins 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41017810P | 2010-11-04 | 2010-11-04 | |
| US61/410,178 | 2010-11-04 | ||
| PCT/JP2011/076017 WO2012060473A1 (en) | 2010-11-04 | 2011-11-04 | Method of efficiently establishing induced pluripotent stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544069A JP2013544069A (ja) | 2013-12-12 |
| JP2013544069A5 true JP2013544069A5 (OSRAM) | 2014-12-18 |
| JP5888753B2 JP5888753B2 (ja) | 2016-03-22 |
Family
ID=46024582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013512280A Active JP5888753B2 (ja) | 2010-11-04 | 2011-11-04 | 効率的な人工多能性幹細胞の樹立方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9637732B2 (OSRAM) |
| EP (1) | EP2635678A4 (OSRAM) |
| JP (1) | JP5888753B2 (OSRAM) |
| WO (1) | WO2012060473A1 (OSRAM) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014013664A2 (pt) | 2011-12-05 | 2020-11-03 | Factor Bioscience Inc. | métodos e produtos para transfectar células |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| BR122019025681B1 (pt) | 2012-11-01 | 2023-04-18 | Factor Bioscience Inc | Método para inserir uma sequência de ácido nucleico em uma localização segura de um genoma de uma célula |
| US9770489B2 (en) | 2014-01-31 | 2017-09-26 | Factor Bioscience Inc. | Methods and products for nucleic acid production and delivery |
| US11241505B2 (en) | 2015-02-13 | 2022-02-08 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| IL263224B2 (en) | 2016-05-25 | 2024-03-01 | Inst Nat Sante Rech Med | Use of a histone deacetylase inhibitor and a population of inactivated pluripotent cells for treating cancer |
| US10576167B2 (en) | 2016-08-17 | 2020-03-03 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CA3083158A1 (en) | 2017-11-24 | 2019-05-31 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods and compositions for treating cancers |
| US20210236633A1 (en) | 2018-08-06 | 2021-08-05 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and compositions for treating cancers |
| JP2022535192A (ja) | 2019-05-14 | 2022-08-05 | アレフ ファームス リミテッド | 多能性細胞凝集体およびそれらの使用 |
| KR20220039719A (ko) | 2019-07-03 | 2022-03-29 | 팩터 바이오사이언스 인크. | 양이온성 지질 및 이의 용도 |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| US12492372B2 (en) | 2020-11-24 | 2025-12-09 | Monash University | Induced stem cells |
| WO2022109667A1 (en) | 2020-11-24 | 2022-06-02 | Monash University | Methods and cellular structures |
| WO2022207889A1 (en) | 2021-04-01 | 2022-10-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Liver organoid manufacturing methods, liver organoids obtained with the same, and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ307399A0 (en) * | 1999-09-24 | 1999-10-21 | Luminis Pty Limited | Cell cycle control |
| US9567591B2 (en) * | 2003-05-15 | 2017-02-14 | Mello Biotechnology, Inc. | Generation of human embryonic stem-like cells using intronic RNA |
| EP4223769A3 (en) | 2005-12-13 | 2023-11-01 | Kyoto University | Nuclear reprogramming factor |
| EP3878949B1 (en) | 2007-04-07 | 2025-06-04 | Whitehead Institute for Biomedical Research | Reprogramming of somatic cells |
| AU2008297024B2 (en) | 2007-10-31 | 2014-08-28 | Kyoto University | Nuclear reprogramming method |
| JP5945385B2 (ja) | 2008-01-16 | 2016-07-05 | リン、シー−ランLIN, Shi−Lung | 誘導性組換えｒｎａ因子を用いた腫瘍のない多能性胚性幹様細胞の生成 |
| WO2009157201A1 (en) | 2008-06-26 | 2009-12-30 | Osaka University | Method and kit for preparing ips cells |
| JP5340265B2 (ja) | 2008-06-27 | 2013-11-13 | 国立大学法人京都大学 | 効率的な人工多能性幹細胞の樹立方法 |
| EP2295538B1 (en) * | 2008-07-07 | 2015-10-21 | Takara Bio Inc. | Method for production of pluripotent stem cell |
-
2011
- 2011-11-04 WO PCT/JP2011/076017 patent/WO2012060473A1/en not_active Ceased
- 2011-11-04 US US13/824,087 patent/US9637732B2/en active Active
- 2011-11-04 JP JP2013512280A patent/JP5888753B2/ja active Active
- 2011-11-04 EP EP11838120.1A patent/EP2635678A4/en not_active Withdrawn
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