JP5885749B2 - 炎症性腸疾患および／または過敏性腸症候群の治療におけるメキシプロスチルの使用 - Google Patents
炎症性腸疾患および／または過敏性腸症候群の治療におけるメキシプロスチルの使用 Download PDFInfo
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- JP5885749B2 JP5885749B2 JP2013534433A JP2013534433A JP5885749B2 JP 5885749 B2 JP5885749 B2 JP 5885749B2 JP 2013534433 A JP2013534433 A JP 2013534433A JP 2013534433 A JP2013534433 A JP 2013534433A JP 5885749 B2 JP5885749 B2 JP 5885749B2
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- 239000002244 precipitate Substances 0.000 description 1
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- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
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- NCEXYHBECQHGNR-QZQOTICOSA-N sulfasalazine Chemical compound C1=C(O)C(C(=O)O)=CC(\N=N\C=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-QZQOTICOSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/606—Salicylic acid; Derivatives thereof having amino groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A001908 | 2010-10-19 | ||
| ITMI2010A001908A IT1402047B1 (it) | 2010-10-19 | 2010-10-19 | Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali |
| PCT/IB2011/054627 WO2012052918A1 (en) | 2010-10-19 | 2011-10-18 | Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544795A JP2013544795A (ja) | 2013-12-19 |
| JP2013544795A5 JP2013544795A5 (enExample) | 2014-08-14 |
| JP5885749B2 true JP5885749B2 (ja) | 2016-03-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013534433A Expired - Fee Related JP5885749B2 (ja) | 2010-10-19 | 2011-10-18 | 炎症性腸疾患および／または過敏性腸症候群の治療におけるメキシプロスチルの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20130202704A1 (enExample) |
| EP (1) | EP2629778B1 (enExample) |
| JP (1) | JP5885749B2 (enExample) |
| KR (1) | KR20140008306A (enExample) |
| CN (1) | CN103167874A (enExample) |
| BR (1) | BR112013009185A2 (enExample) |
| CA (1) | CA2812891A1 (enExample) |
| IT (1) | IT1402047B1 (enExample) |
| WO (1) | WO2012052918A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| US10154964B2 (en) | 2011-09-07 | 2018-12-18 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| AU2011248587A1 (en) * | 2011-11-09 | 2013-05-23 | Cosmo Technologies Ltd | Controlled release and taste masking oral pharmaceutical composition |
| CN104379140A (zh) * | 2012-04-23 | 2015-02-25 | 苏坎波公司 | 用于治疗具有腹泻的肠易激综合征的方法 |
| EP3291818B1 (en) * | 2015-05-04 | 2019-10-30 | The Board of Trustees of the Leland Stanford Junior University | Compositions and methods for delivering therapeutic agents into the colon |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5219885A (en) * | 1987-02-16 | 1993-06-15 | Froelich Juergen | Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration |
| DE3704825A1 (de) * | 1987-02-16 | 1988-08-25 | Froelich Juergen | Prostaglandin e1-derivate als pharmazeutische wirkstoffe und diese verbindungen enthaltende arzneimittel insbesondere zur transkutanen anwendung |
| ATE82748T1 (de) * | 1988-01-28 | 1992-12-15 | Merrell Dow Pharma | Verfahren und zwischenprodukte. |
| US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
| RU2246293C2 (ru) * | 1999-06-14 | 2005-02-20 | Космо С.П.А. | Фармацевтические композиции для перорального введения с регулируемым высвобождением активного ингредиента и маскируемым вкусом |
| ITMI991316A1 (it) * | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
| DE60001623T2 (de) * | 1999-12-03 | 2003-12-18 | Pfizer Products Inc., Groton | Sulfamoylheteroarylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel |
| US20050159485A1 (en) * | 2002-01-04 | 2005-07-21 | Jost-Price Edward R. | Combinations for the treatment of immunoinflammatory disorders and proliferative skin diseases |
| WO2004060377A1 (en) * | 2002-12-27 | 2004-07-22 | Sucampo Ag | Derivatives of prostaglandins for treating abdominal discomfort |
| ATE435853T1 (de) * | 2004-07-02 | 2009-07-15 | Allergan Inc | Prostaglandinanaloga |
-
2010
- 2010-10-19 IT ITMI2010A001908A patent/IT1402047B1/it active
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2011
- 2011-10-18 WO PCT/IB2011/054627 patent/WO2012052918A1/en not_active Ceased
- 2011-10-18 CA CA2812891A patent/CA2812891A1/en not_active Abandoned
- 2011-10-18 KR KR1020137011710A patent/KR20140008306A/ko not_active Withdrawn
- 2011-10-18 EP EP11799304.8A patent/EP2629778B1/en not_active Not-in-force
- 2011-10-18 BR BR112013009185A patent/BR112013009185A2/pt not_active IP Right Cessation
- 2011-10-18 CN CN2011800502426A patent/CN103167874A/zh active Pending
- 2011-10-18 US US13/880,125 patent/US20130202704A1/en not_active Abandoned
- 2011-10-18 JP JP2013534433A patent/JP5885749B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20130202704A1 (en) | 2013-08-08 |
| BR112013009185A2 (pt) | 2016-07-26 |
| KR20140008306A (ko) | 2014-01-21 |
| ITMI20101908A1 (it) | 2012-04-20 |
| WO2012052918A1 (en) | 2012-04-26 |
| IT1402047B1 (it) | 2013-08-28 |
| CA2812891A1 (en) | 2012-04-26 |
| JP2013544795A (ja) | 2013-12-19 |
| EP2629778A1 (en) | 2013-08-28 |
| CN103167874A (zh) | 2013-06-19 |
| EP2629778B1 (en) | 2016-09-21 |
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