JP2013544795A5 - - Google Patents
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- Publication number
- JP2013544795A5 JP2013544795A5 JP2013534433A JP2013534433A JP2013544795A5 JP 2013544795 A5 JP2013544795 A5 JP 2013544795A5 JP 2013534433 A JP2013534433 A JP 2013534433A JP 2013534433 A JP2013534433 A JP 2013534433A JP 2013544795 A5 JP2013544795 A5 JP 2013544795A5
- Authority
- JP
- Japan
- Prior art keywords
- mexiprostil
- ibs
- prevention
- treatment
- matrix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- GGDWDKDPRJFMHD-ZXYUVVQBSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(e,3r)-3-hydroxy-4-methoxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(OC)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC GGDWDKDPRJFMHD-ZXYUVVQBSA-N 0.000 claims 10
- 229950000086 mexiprostil Drugs 0.000 claims 10
- 208000002551 irritable bowel syndrome Diseases 0.000 claims 7
- 239000011159 matrix material Substances 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 5
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 4
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010774 Constipation Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 206010012735 Diarrhoea Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 229960004436 budesonide Drugs 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000013270 controlled release Methods 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 150000002634 lipophilic molecules Chemical class 0.000 claims 1
- 230000008018 melting Effects 0.000 claims 1
- 238000002844 melting Methods 0.000 claims 1
- KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical compound NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 claims 1
- 229960004963 mesalazine Drugs 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2010A001908A IT1402047B1 (it) | 2010-10-19 | 2010-10-19 | Uso del mexiprostil nel trattamento delle malattie infiammatorie intestinali |
| ITMI2010A001908 | 2010-10-19 | ||
| PCT/IB2011/054627 WO2012052918A1 (en) | 2010-10-19 | 2011-10-18 | Use of mexiprostil in the treatment of inflammatory bowel disease and/or of irritable bowel syndrome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013544795A JP2013544795A (ja) | 2013-12-19 |
| JP2013544795A5 true JP2013544795A5 (enExample) | 2014-08-14 |
| JP5885749B2 JP5885749B2 (ja) | 2016-03-15 |
Family
ID=43738034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013534433A Expired - Fee Related JP5885749B2 (ja) | 2010-10-19 | 2011-10-18 | 炎症性腸疾患および／または過敏性腸症候群の治療におけるメキシプロスチルの使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20130202704A1 (enExample) |
| EP (1) | EP2629778B1 (enExample) |
| JP (1) | JP5885749B2 (enExample) |
| KR (1) | KR20140008306A (enExample) |
| CN (1) | CN103167874A (enExample) |
| BR (1) | BR112013009185A2 (enExample) |
| CA (1) | CA2812891A1 (enExample) |
| IT (1) | IT1402047B1 (enExample) |
| WO (1) | WO2012052918A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8895064B2 (en) | 1999-06-14 | 2014-11-25 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| US10154964B2 (en) | 2011-09-07 | 2018-12-18 | Cosmo Technologies Limited | Controlled release and taste masking oral pharmaceutical composition |
| AU2011248587A1 (en) * | 2011-11-09 | 2013-05-23 | Cosmo Technologies Ltd | Controlled release and taste masking oral pharmaceutical composition |
| WO2013161973A1 (en) * | 2012-04-23 | 2013-10-31 | Sucampo Ag | Method for treating irritable bowel syndrome with diarrhea |
| KR20170142181A (ko) * | 2015-05-04 | 2017-12-27 | 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 주니어 유니버시티 | 결장내로 치료제 전달을 위한 조성물 및 방법 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3704825A1 (de) * | 1987-02-16 | 1988-08-25 | Froelich Juergen | Prostaglandin e1-derivate als pharmazeutische wirkstoffe und diese verbindungen enthaltende arzneimittel insbesondere zur transkutanen anwendung |
| US5219885A (en) * | 1987-02-16 | 1993-06-15 | Froelich Juergen | Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration |
| EP0325869B1 (en) * | 1988-01-28 | 1992-11-25 | Merrell Dow Pharmaceuticals Inc. | Novel processes and intermediates |
| US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
| WO2000076478A1 (en) * | 1999-06-14 | 2000-12-21 | Cosmo S.P.A. | Controlled release and taste masking oral pharmaceutical compositions |
| ITMI991316A1 (it) * | 1999-06-14 | 2000-12-14 | Cip Ninety Two 92 S A | Composizioni farmaceutiche orali a rilascio modificato di mesalazina |
| DK1104760T3 (da) * | 1999-12-03 | 2003-06-30 | Pfizer Prod Inc | Sulfamoylheteroarylpyrazolforbindelser som anti-inflammatoriske/analgetiske midler |
| US20050159485A1 (en) * | 2002-01-04 | 2005-07-21 | Jost-Price Edward R. | Combinations for the treatment of immunoinflammatory disorders and proliferative skin diseases |
| JP4889219B2 (ja) * | 2002-12-27 | 2012-03-07 | スキャンポ・アーゲー | 腹部不快感の処置のためのプロスタグランジン誘導体 |
| ATE435853T1 (de) * | 2004-07-02 | 2009-07-15 | Allergan Inc | Prostaglandinanaloga |
-
2010
- 2010-10-19 IT ITMI2010A001908A patent/IT1402047B1/it active
-
2011
- 2011-10-18 CN CN2011800502426A patent/CN103167874A/zh active Pending
- 2011-10-18 EP EP11799304.8A patent/EP2629778B1/en not_active Not-in-force
- 2011-10-18 US US13/880,125 patent/US20130202704A1/en not_active Abandoned
- 2011-10-18 WO PCT/IB2011/054627 patent/WO2012052918A1/en not_active Ceased
- 2011-10-18 BR BR112013009185A patent/BR112013009185A2/pt not_active IP Right Cessation
- 2011-10-18 KR KR1020137011710A patent/KR20140008306A/ko not_active Withdrawn
- 2011-10-18 JP JP2013534433A patent/JP5885749B2/ja not_active Expired - Fee Related
- 2011-10-18 CA CA2812891A patent/CA2812891A1/en not_active Abandoned
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