JP5860409B2 - 徐放性核酸マトリックス組成物 - Google Patents

徐放性核酸マトリックス組成物 Download PDF

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JP5860409B2
JP5860409B2 JP2012548536A JP2012548536A JP5860409B2 JP 5860409 B2 JP5860409 B2 JP 5860409B2 JP 2012548536 A JP2012548536 A JP 2012548536A JP 2012548536 A JP2012548536 A JP 2012548536A JP 5860409 B2 JP5860409 B2 JP 5860409B2
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another embodiment
matrix composition
nucleic acid
lipid
matrix
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JP2013517265A (ja
JP2013517265A5 (enExample
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エマヌエル,ノアム
ローゼンフェルド,ヨセフ
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ポリピッド リミテッド
ポリピッド リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
JP2012548536A 2010-01-19 2011-01-18 徐放性核酸マトリックス組成物 Active JP5860409B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29604010P 2010-01-19 2010-01-19
US61/296,040 2010-01-19
PCT/IL2011/000054 WO2011089595A2 (en) 2010-01-19 2011-01-18 Sustained-release nucleic acid matrix compositions

Publications (3)

Publication Number Publication Date
JP2013517265A JP2013517265A (ja) 2013-05-16
JP2013517265A5 JP2013517265A5 (enExample) 2014-03-06
JP5860409B2 true JP5860409B2 (ja) 2016-02-16

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Family Applications (1)

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JP2012548536A Active JP5860409B2 (ja) 2010-01-19 2011-01-18 徐放性核酸マトリックス組成物

Country Status (7)

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US (2) US8795726B2 (enExample)
EP (1) EP2525778B1 (enExample)
JP (1) JP5860409B2 (enExample)
CN (1) CN102892406B (enExample)
AU (1) AU2011208374B2 (enExample)
CA (1) CA2783001C (enExample)
WO (1) WO2011089595A2 (enExample)

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JP2016023148A (ja) * 2014-07-17 2016-02-08 富士フイルム株式会社 脂質粒子の製造法および脂質粒子を有する核酸送達キャリア
HUE056523T2 (hu) * 2014-10-02 2022-02-28 Polypid Ltd Készítmények és eljárások mûtéti sebfertõzések kezelésére és megelõzésére
BR112020006136A2 (pt) * 2017-09-26 2020-10-06 Nanomi B.V. método para a preparação de micropartículas pela técnica de dupla emulsão
CN107823725B (zh) * 2017-10-11 2020-10-09 上海君联医疗设备有限公司 一种可延期回收的血栓滤器及其制作方法
JP6388700B2 (ja) * 2017-10-20 2018-09-12 富士フイルム株式会社 脂質粒子の製造法および脂質粒子を有する核酸送達キャリア
US11464860B2 (en) 2017-10-27 2022-10-11 Massachusetts Institute Of Technology Poly (beta-amino esters) and uses thereof
KR20210093232A (ko) 2018-10-09 2021-07-27 더 유니버시티 오브 브리티시 콜롬비아 유기용매와 세제가 없는 형질감염 적격 소포를 포함하는 조성물과 시스템 및 관련 방법
CA3117781A1 (en) * 2018-10-26 2020-04-30 Massachusetts Institute Of Technology Polymer-lipids and compositions
WO2022192176A1 (en) 2021-03-09 2022-09-15 Massachusetts Institute Of Technology Branched poly(-amino esters) for the delivery of nucleic acids

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Also Published As

Publication number Publication date
US20140335165A1 (en) 2014-11-13
CA2783001A1 (en) 2011-07-28
US8795726B2 (en) 2014-08-05
CN102892406A (zh) 2013-01-23
AU2011208374A1 (en) 2012-06-21
AU2011208374B2 (en) 2016-09-08
EP2525778A2 (en) 2012-11-28
CA2783001C (en) 2017-12-12
EP2525778B1 (en) 2018-08-01
US20120294944A1 (en) 2012-11-22
EP2525778A4 (en) 2013-07-03
JP2013517265A (ja) 2013-05-16
WO2011089595A2 (en) 2011-07-28
CN102892406B (zh) 2015-04-08
WO2011089595A3 (en) 2011-10-20
US9616032B2 (en) 2017-04-11

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