JP5847704B2 - 超臨界co2を用いて含浸する方法 - Google Patents

超臨界co2を用いて含浸する方法 Download PDF

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JP5847704B2
JP5847704B2 JP2012510301A JP2012510301A JP5847704B2 JP 5847704 B2 JP5847704 B2 JP 5847704B2 JP 2012510301 A JP2012510301 A JP 2012510301A JP 2012510301 A JP2012510301 A JP 2012510301A JP 5847704 B2 JP5847704 B2 JP 5847704B2
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active substance
pharmaceutical carrier
polymeric pharmaceutical
supercritical
impregnated
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Japanese (ja)
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JP2012526775A5 (enExample
JP2012526775A (ja
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ユベール、ロシャール
ベルナール、フレス
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ピエール、ファーブル、メディカマン
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
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  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Nutrition Science (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012510301A 2009-05-15 2010-05-12 超臨界co2を用いて含浸する方法 Expired - Fee Related JP5847704B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0953221A FR2945449B1 (fr) 2009-05-15 2009-05-15 Procede d'impregnation par co2 supercritique
FR0953221 2009-05-15
PCT/EP2010/056582 WO2010130799A2 (fr) 2009-05-15 2010-05-12 Procede d'impregnation par co2 supercritique

Publications (3)

Publication Number Publication Date
JP2012526775A JP2012526775A (ja) 2012-11-01
JP2012526775A5 JP2012526775A5 (enExample) 2015-06-25
JP5847704B2 true JP5847704B2 (ja) 2016-01-27

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JP2012510301A Expired - Fee Related JP5847704B2 (ja) 2009-05-15 2010-05-12 超臨界co2を用いて含浸する方法

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US (1) US9028806B2 (enExample)
EP (1) EP2429499B1 (enExample)
JP (1) JP5847704B2 (enExample)
KR (1) KR101752929B1 (enExample)
ES (1) ES2538346T3 (enExample)
FR (1) FR2945449B1 (enExample)
WO (1) WO2010130799A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2974092B1 (fr) * 2011-04-13 2014-12-05 Commissariat Energie Atomique Procede de fabrication de composants par pim, base sur l'utilisation de fibres ou fils organiques, avantageusement couplee a l'utilisation de co2 supercritique
CA2976004C (en) * 2015-02-05 2020-06-02 Colorado Can Llc Purified cbd and cbda, and methods, compositions and products employing cbd or cbda
US10403315B2 (en) 2015-05-06 2019-09-03 Western Digital Technologies, Inc. Near-field transducer for heat assisted magnetic recording comprising of thermally stable material layer
US20180271826A1 (en) * 2017-03-22 2018-09-27 Colorado Can Llc Dry powders of cannabinoids and methods for preparing dry powders
CN113679691B (zh) * 2021-07-28 2022-12-13 内蒙古东绿生态科技研究院有限公司 蒙艾中黄酮类物质的微囊包合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340614A (en) * 1993-02-11 1994-08-23 Minnesota Mining And Manufacturing Company Methods of polymer impregnation
FR2752732B1 (fr) * 1996-08-28 1998-11-20 Pf Medicament Forme galenique a liberation prolongee de milnacipran
IT1296464B1 (it) * 1997-11-19 1999-06-25 Vectorpharma Int Composizioni farmaceutiche in forma di polveri di polimeri reticolati caricati con farmaci e relativo processo di preparazione mediante
IT1318404B1 (it) * 2000-03-17 2003-08-25 Eurand Int Processo per la preparazione di formulazioni a rilascio accelerato conimpiego di fluidi compressi.
EP1894565B1 (en) * 2005-06-10 2013-10-30 Pierre Fabre Médicament S.A. Stabilized milnacipran formulation

Also Published As

Publication number Publication date
FR2945449B1 (fr) 2012-10-05
KR20120017060A (ko) 2012-02-27
ES2538346T3 (es) 2015-06-19
KR101752929B1 (ko) 2017-06-30
JP2012526775A (ja) 2012-11-01
WO2010130799A3 (fr) 2011-05-19
EP2429499B1 (fr) 2015-03-25
WO2010130799A2 (fr) 2010-11-18
FR2945449A1 (fr) 2010-11-19
US20120064130A1 (en) 2012-03-15
US9028806B2 (en) 2015-05-12
EP2429499A2 (fr) 2012-03-21

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