JP5841952B2 - 腫瘍性疾患の治療的処置にて用いるための成体幹細胞由来の微細小胞（ｍｖ） - Google Patents
腫瘍性疾患の治療的処置にて用いるための成体幹細胞由来の微細小胞（ｍｖ） Download PDFInfo
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10425052.7 | 2010-03-02 | ||
| EP10425052A EP2363136A1 (en) | 2010-03-02 | 2010-03-02 | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| PCT/EP2011/052945 WO2011107437A1 (en) | 2010-03-02 | 2011-02-28 | Microvesicles (mvs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
Publications (3)
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| JP2013520971A JP2013520971A (ja) | 2013-06-10 |
| JP2013520971A5 JP2013520971A5 (https=) | 2014-04-03 |
| JP5841952B2 true JP5841952B2 (ja) | 2016-01-13 |
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| EP (2) | EP2363136A1 (https=) |
| JP (1) | JP5841952B2 (https=) |
| CN (1) | CN102781454B (https=) |
| DK (1) | DK2542250T3 (https=) |
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| HU (1) | HUE026292T2 (https=) |
| PL (1) | PL2542250T3 (https=) |
| PT (1) | PT2542250E (https=) |
| WO (1) | WO2011107437A1 (https=) |
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| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| TWI762890B (zh) | 2010-05-12 | 2022-05-01 | 開曼群島商英瑞金公司 | 生物活性腎細胞 |
| ITRM20110403A1 (it) * | 2011-07-28 | 2013-01-29 | Ospedale Pediatrico Bambino Gesu | Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori. |
| CN102357071B (zh) * | 2011-10-26 | 2013-10-23 | 重庆医科大学附属儿童医院 | 载紫杉醇纳米微泡及其制备方法 |
| KR102246369B1 (ko) * | 2011-11-30 | 2021-04-29 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US11286463B2 (en) | 2012-03-08 | 2022-03-29 | Advanced ReGen Medical Technologies, LLC | Reprogramming of aged adult stem cells |
| US9745551B2 (en) | 2012-07-12 | 2017-08-29 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CR20160307A (es) | 2013-12-20 | 2016-11-08 | Advanced Regen Medical Tech Llc | Composiciones para la restauración de células y métodos para la preparación y utilización de las mismas |
| US10772911B2 (en) | 2013-12-20 | 2020-09-15 | Advanced ReGen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| EP4445915A3 (en) * | 2014-03-24 | 2025-01-22 | Advanced Regen Medical Technologies, LLC | Cell free compositions for cellular restoration and methods of making and using same |
| WO2015179301A1 (en) * | 2014-05-19 | 2015-11-26 | Eleftherios Papoutsakis | Megakaryocytic particles and microparticles for cell therapy & fate modification of stem and progenitor cells |
| EP3436081A4 (en) | 2016-04-29 | 2019-07-24 | Advanced Regen Medical Technologies, LLC | Microrna compositions and methods of making and using same |
| US11395832B2 (en) | 2017-12-14 | 2022-07-26 | Unicyte Ev Ag | Pharmaceutical carriers containing miRNAs for use in the treatment of renal cancer |
| US10717981B2 (en) | 2018-01-18 | 2020-07-21 | Advanced ReGen Medical Technologies, LLC | Therapeutic compositions and methods of making and using the same |
| WO2019197442A1 (en) * | 2018-04-12 | 2019-10-17 | Unicyte Ev Ag | A combination of active ingredients for the treatment of tumor |
| CN111494417B (zh) * | 2020-02-10 | 2024-04-09 | 寇晓星 | 诱导性细胞外囊泡在制备治疗肿瘤药物中的应用 |
| CA3178268A1 (en) | 2020-05-11 | 2021-11-18 | Jonathan Thon | Compositions and methods related to megakaryocyte-derived extracellular vesicles |
| KR102601831B1 (ko) * | 2020-09-23 | 2023-11-14 | 대한민국 | 고형암 증식 억제 효과를 갖는 개과동물의 엑소좀 |
| JP2024518770A (ja) | 2021-04-26 | 2024-05-02 | ストーム バイオ インコーポレイテッド | ファンコニ貧血のための巨核球由来細胞外小胞に関する組成物及び方法 |
| EP4534649A1 (en) * | 2023-10-03 | 2025-04-09 | Unicyte AG | A method of qualifying as pharmaceutically active a batch of undifferentiated adult stem cells having the potential to differentiate along the hepatic lineage |
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| US6088613A (en) * | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
| WO1998033486A1 (en) * | 1997-01-30 | 1998-08-06 | Quadrant Healthcare (Uk) Limited | Microparticles and their use in cancer treatment |
| ES2244169T3 (es) * | 1998-02-09 | 2005-12-01 | Bracco International B.V. | Suministro direccionado de medios biologicamente activos. |
| US20020177551A1 (en) * | 2000-05-31 | 2002-11-28 | Terman David S. | Compositions and methods for treatment of neoplastic disease |
| US7128903B2 (en) * | 2001-10-03 | 2006-10-31 | Innovative Pharmaceutical Concepts (Ipc) Inc. | Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same |
| WO2005121369A2 (en) * | 2004-06-02 | 2005-12-22 | Sourcepharm, Inc. | Rna-containing microvesicles and methods therefor |
| US8148335B2 (en) * | 2004-06-23 | 2012-04-03 | Children's Hospital & Research Center Oakland | De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy |
| GB0501129D0 (en) * | 2005-01-19 | 2005-02-23 | Ribostem Ltd | Method of treatment by administration of RNA |
| WO2006126219A1 (en) | 2005-05-26 | 2006-11-30 | Fresenius Medical Care Deutschland G.M.B.H. | Liver progenitor cells |
| TWI479559B (zh) | 2007-06-28 | 2015-04-01 | 量子全球技術公司 | 以選擇性噴灑蝕刻來清潔腔室部件的方法和設備 |
| ES2575868T3 (es) * | 2007-09-14 | 2016-07-01 | The Ohio State University Research Foundation | Expresión de miARN en microvesículas de sangre periférica humana y sus usos |
| EP2209481B1 (en) | 2007-10-15 | 2013-03-13 | Fresenius Medical Care Deutschland GmbH | Use of microvesicles (mvs) for preparing a medicament having adjuvant activity on endothelial cell transplantation, particularly in the treatment of diabetes by pancreatic islet transplantation, and related method |
| ES2523098T3 (es) * | 2007-10-29 | 2014-11-20 | Fresenius Medical Care Deutschland Gmbh | Microvesícula (MV) derivada de células madre para su uso en la inhibición de la apoptosis inducida por un agente citostático |
| CA2711218C (en) * | 2008-01-04 | 2019-08-06 | Lydac Neuroscience Limited | A method of producing a population of differentiated cells |
| CN102014934B (zh) * | 2008-02-22 | 2014-08-20 | 新加坡科技研究局 | 间充质干细胞颗粒 |
| EP2186883A1 (en) | 2008-11-04 | 2010-05-19 | Fresenius Medical Care | An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney |
| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
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- 2010-03-02 EP EP10425052A patent/EP2363136A1/en not_active Withdrawn
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2011
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- 2011-02-28 DK DK11705585.5T patent/DK2542250T3/en active
- 2011-02-28 WO PCT/EP2011/052945 patent/WO2011107437A1/en not_active Ceased
- 2011-02-28 ES ES11705585.5T patent/ES2554492T3/es active Active
- 2011-02-28 PL PL11705585T patent/PL2542250T3/pl unknown
- 2011-02-28 PT PT117055855T patent/PT2542250E/pt unknown
- 2011-02-28 EP EP11705585.5A patent/EP2542250B1/en active Active
- 2011-02-28 HU HUE11705585A patent/HUE026292T2/en unknown
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2023
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Also Published As
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| PL2542250T3 (pl) | 2016-04-29 |
| CN102781454A (zh) | 2012-11-14 |
| EP2542250A1 (en) | 2013-01-09 |
| JP2013520971A (ja) | 2013-06-10 |
| PT2542250E (pt) | 2015-12-09 |
| US20120321723A1 (en) | 2012-12-20 |
| US20230248774A1 (en) | 2023-08-10 |
| HUE026292T2 (en) | 2016-05-30 |
| US20170348356A1 (en) | 2017-12-07 |
| EP2542250B1 (en) | 2015-08-26 |
| CN102781454B (zh) | 2015-12-16 |
| DK2542250T3 (en) | 2015-12-07 |
| ES2554492T3 (es) | 2015-12-21 |
| WO2011107437A1 (en) | 2011-09-09 |
| EP2363136A1 (en) | 2011-09-07 |
| US9717760B2 (en) | 2017-08-01 |
| US10105395B2 (en) | 2018-10-23 |
| US20190060369A1 (en) | 2019-02-28 |
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