PL2542250T3 - Mikropęcherzyki (mvs) pochodzące z dorosłych komórek macierzystych do zastosowania w terapeutycznym leczeniu choroby nowotworowej - Google Patents

Mikropęcherzyki (mvs) pochodzące z dorosłych komórek macierzystych do zastosowania w terapeutycznym leczeniu choroby nowotworowej

Info

Publication number
PL2542250T3
PL2542250T3 PL11705585T PL11705585T PL2542250T3 PL 2542250 T3 PL2542250 T3 PL 2542250T3 PL 11705585 T PL11705585 T PL 11705585T PL 11705585 T PL11705585 T PL 11705585T PL 2542250 T3 PL2542250 T3 PL 2542250T3
Authority
PL
Poland
Prior art keywords
microvesicles
mvs
derived
stem cells
therapeutic treatment
Prior art date
Application number
PL11705585T
Other languages
English (en)
Polish (pl)
Inventor
Stefania Bruno
Sanchez Maria Beatriz Herrera
Valentina Fonsato
Giovanni Camussi
Ciro Tetta
Original Assignee
Fresenius Medical Care Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care Deutschland Gmbh filed Critical Fresenius Medical Care Deutschland Gmbh
Publication of PL2542250T3 publication Critical patent/PL2542250T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL11705585T 2010-03-02 2011-02-28 Mikropęcherzyki (mvs) pochodzące z dorosłych komórek macierzystych do zastosowania w terapeutycznym leczeniu choroby nowotworowej PL2542250T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10425052A EP2363136A1 (en) 2010-03-02 2010-03-02 Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
EP11705585.5A EP2542250B1 (en) 2010-03-02 2011-02-28 Microvesicles (mvs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
PCT/EP2011/052945 WO2011107437A1 (en) 2010-03-02 2011-02-28 Microvesicles (mvs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease

Publications (1)

Publication Number Publication Date
PL2542250T3 true PL2542250T3 (pl) 2016-04-29

Family

ID=42306621

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11705585T PL2542250T3 (pl) 2010-03-02 2011-02-28 Mikropęcherzyki (mvs) pochodzące z dorosłych komórek macierzystych do zastosowania w terapeutycznym leczeniu choroby nowotworowej

Country Status (10)

Country Link
US (4) US9717760B2 (https=)
EP (2) EP2363136A1 (https=)
JP (1) JP5841952B2 (https=)
CN (1) CN102781454B (https=)
DK (1) DK2542250T3 (https=)
ES (1) ES2554492T3 (https=)
HU (1) HUE026292T2 (https=)
PL (1) PL2542250T3 (https=)
PT (1) PT2542250E (https=)
WO (1) WO2011107437A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2363136A1 (en) * 2010-03-02 2011-09-07 Fresenius Medical Care Deutschland GmbH Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
CN103154236B (zh) 2010-05-12 2016-08-31 再生医学Tx有限责任公司 生物活性肾细胞
ITRM20110403A1 (it) * 2011-07-28 2013-01-29 Ospedale Pediatrico Bambino Gesu Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori.
CN102357071B (zh) * 2011-10-26 2013-10-23 重庆医科大学附属儿童医院 载紫杉醇纳米微泡及其制备方法
US8961956B2 (en) 2011-11-30 2015-02-24 Ocata Therapeutics, Inc. Mesenchymal stromal cells and uses related thereto
SI2785359T1 (sl) 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
US11286463B2 (en) 2012-03-08 2022-03-29 Advanced ReGen Medical Technologies, LLC Reprogramming of aged adult stem cells
HK1208054A1 (en) 2012-07-12 2016-02-19 爱姆斯坦生物技术公司 Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
US10772911B2 (en) 2013-12-20 2020-09-15 Advanced ReGen Medical Technologies, LLC Cell free compositions for cellular restoration and methods of making and using same
US20150174166A1 (en) 2013-12-20 2015-06-25 Advanced ReGen Medical Technologies, LLC Compositions for Cellular Restoration and Methods of Making and Using Same
EP4445915A3 (en) * 2014-03-24 2025-01-22 Advanced Regen Medical Technologies, LLC Cell free compositions for cellular restoration and methods of making and using same
US10538738B2 (en) * 2014-05-19 2020-01-21 Eleftherios Papoutsakis Megakaryocytic particles and microparticles for cell therapy and fate modification of stem and progenitor cells
US11203754B2 (en) 2016-04-29 2021-12-21 Advanced ReGen Medical Technologies, LLC Microrna compositions and methods of making and using same
CN111601890B (zh) * 2017-12-14 2024-04-19 联合细胞Ev股份公司 用于治疗肾癌的包含miRNA的药物载体
EP3740576A4 (en) 2018-01-18 2021-10-20 Advanced Regen Medical Technologies, LLC THERAPEUTIC COMPOSITIONS AND THEIR PREPARATION AND USE METHODS
WO2019197442A1 (en) * 2018-04-12 2019-10-17 Unicyte Ev Ag A combination of active ingredients for the treatment of tumor
CN111494417B (zh) * 2020-02-10 2024-04-09 寇晓星 诱导性细胞外囊泡在制备治疗肿瘤药物中的应用
US20230190815A1 (en) 2020-05-11 2023-06-22 Strm.Bio Incorporated Compositions and methods related to megakaryocyte-derived extracellular vesicles
KR102601831B1 (ko) * 2020-09-23 2023-11-14 대한민국 고형암 증식 억제 효과를 갖는 개과동물의 엑소좀
AU2022264498A1 (en) 2021-04-26 2023-09-28 Strm.Bio Incorporated Compositions and methods related to megakaryocyte-derived extracellular vesicles for fanconi anemia
EP4534649A1 (en) * 2023-10-03 2025-04-09 Unicyte AG A method of qualifying as pharmaceutically active a batch of undifferentiated adult stem cells having the potential to differentiate along the hepatic lineage

Family Cites Families (17)

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US6088613A (en) * 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
EP0964676A1 (en) * 1997-01-30 1999-12-22 Quadrant Healthcare (UK) Limited Microparticles and their use in cancer treatment
JP4772958B2 (ja) * 1998-02-09 2011-09-14 ブラッコ・リサーチ・ソシエテ・アノニム 生物学的に活性な媒質の標的に向けた送達
US20020177551A1 (en) * 2000-05-31 2002-11-28 Terman David S. Compositions and methods for treatment of neoplastic disease
US7128903B2 (en) * 2001-10-03 2006-10-31 Innovative Pharmaceutical Concepts (Ipc) Inc. Pharmaceutical preparations useful for treating tumors and lesions of the skin and the mucous membranes and methods and kits using same
JP2008501336A (ja) * 2004-06-02 2008-01-24 ソースフアーム・インコーポレイテツド Ｒｎａを含有する微小胞およびそのための方法
US8148335B2 (en) * 2004-06-23 2012-04-03 Children's Hospital & Research Center Oakland De-N-acetyl sialic acid antigens, antibodies thereto, and methods of use in cancer therapy
GB0501129D0 (en) * 2005-01-19 2005-02-23 Ribostem Ltd Method of treatment by administration of RNA
WO2006126219A1 (en) 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
TWI479559B (zh) 2007-06-28 2015-04-01 量子全球技術公司 以選擇性噴灑蝕刻來清潔腔室部件的方法和設備
EP2610342B1 (en) * 2007-09-14 2016-05-04 The Ohio State University Research Foundation MiRNA Expression in Human Peripheral Blood Microvesicles and uses Thereof
US20100233216A1 (en) * 2007-10-15 2010-09-16 Vincenzo Cantaluppi Use of microvesicles (mvs) for preparing a medicament having adjuvant activity on endothelial cell transplantation, particularly in the treatment of diabetes by pancreatic islet transplantation, and related method
CN101854941B (zh) * 2007-10-29 2013-03-27 弗雷森纽斯医疗护理德国有限责任公司 衍生自干细胞的微泡(MVs)用于制备用于受损或损伤组织或器官的内皮/上皮再生的药物的用途、以及相关体外和体内方法
AU2009203638C1 (en) * 2008-01-04 2013-07-25 Lydac Neuroscience Limited Microvesicles
EP2254586B1 (en) * 2008-02-22 2015-04-08 Agency For Science, Technology And Research (A*star) Mesenchymal stem cell particles
EP2186883A1 (en) 2008-11-04 2010-05-19 Fresenius Medical Care An isolated multipotent mesenchymal stem cell from human adult glomeruli (hGL-MSC), a method of preparing thereof and uses thereof in the regenerative medicine of the kidney
EP2363136A1 (en) * 2010-03-02 2011-09-07 Fresenius Medical Care Deutschland GmbH Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease

Also Published As

Publication number Publication date
PT2542250E (pt) 2015-12-09
WO2011107437A1 (en) 2011-09-09
HUE026292T2 (en) 2016-05-30
EP2542250A1 (en) 2013-01-09
US20120321723A1 (en) 2012-12-20
EP2542250B1 (en) 2015-08-26
JP5841952B2 (ja) 2016-01-13
JP2013520971A (ja) 2013-06-10
ES2554492T3 (es) 2015-12-21
US20170348356A1 (en) 2017-12-07
CN102781454A (zh) 2012-11-14
US20190060369A1 (en) 2019-02-28
CN102781454B (zh) 2015-12-16
US9717760B2 (en) 2017-08-01
US10105395B2 (en) 2018-10-23
EP2363136A1 (en) 2011-09-07
US20230248774A1 (en) 2023-08-10
DK2542250T3 (en) 2015-12-07

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