JP5784010B2 - 自己免疫性、炎症およびガンの経過を阻害し得る新規なケモカイン結合ポリペプチド - Google Patents

自己免疫性、炎症およびガンの経過を阻害し得る新規なケモカイン結合ポリペプチド Download PDF

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JP5784010B2
JP5784010B2 JP2012515627A JP2012515627A JP5784010B2 JP 5784010 B2 JP5784010 B2 JP 5784010B2 JP 2012515627 A JP2012515627 A JP 2012515627A JP 2012515627 A JP2012515627 A JP 2012515627A JP 5784010 B2 JP5784010 B2 JP 5784010B2
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polypeptide
seq
chemokine
bkt
polypeptides
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JP2012529906A (ja
JP2012529906A5 (OSRAM
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ミカル アブラハム，
ミカル アブラハム，
オルリー アイゼンバーグ，
オルリー アイゼンバーグ，
アムノン ペレド，
アムノン ペレド，
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バイオカイン セラピューティックス リミテッド
バイオカイン セラピューティックス リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K—PEPTIDES
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Biochemistry (AREA)
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  • Diabetes (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
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JP2012515627A 2009-06-15 2010-06-15 自己免疫性、炎症およびガンの経過を阻害し得る新規なケモカイン結合ポリペプチド Expired - Fee Related JP5784010B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21349309P 2009-06-15 2009-06-15
US61/213,493 2009-06-15
PCT/IL2010/000473 WO2010146584A1 (en) 2009-06-15 2010-06-15 Novel chemokine binding polypeptides capable of inhibiting the course of autoimmunity, inflammation and cancer

Publications (3)

Publication Number Publication Date
JP2012529906A JP2012529906A (ja) 2012-11-29
JP2012529906A5 JP2012529906A5 (OSRAM) 2013-08-01
JP5784010B2 true JP5784010B2 (ja) 2015-09-24

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JP2012515627A Expired - Fee Related JP5784010B2 (ja) 2009-06-15 2010-06-15 自己免疫性、炎症およびガンの経過を阻害し得る新規なケモカイン結合ポリペプチド

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US (3) US8685398B2 (OSRAM)
EP (1) EP2443137B1 (OSRAM)
JP (1) JP5784010B2 (OSRAM)
KR (1) KR20120046163A (OSRAM)
CN (1) CN102482324B (OSRAM)
BR (1) BRPI1009716A2 (OSRAM)
CA (1) CA2765188A1 (OSRAM)
DK (1) DK2443137T3 (OSRAM)
HU (1) HUE025294T2 (OSRAM)
MX (1) MX2011013457A (OSRAM)
WO (1) WO2010146584A1 (OSRAM)

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KR20120046163A (ko) 2009-06-15 2012-05-09 바이오카인 테라퓨틱스 리미티드 자가면역, 염증 및 암의 과정을 저해할 수 있는 신규한 케모카인 결합 폴리펩타이드류
WO2012095849A1 (en) 2011-01-10 2012-07-19 Biokine Therapeutics Ltd. Peptides and compositions for the treatment of neuroectodermal derived tumors and retinoblastoma
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
CN107698664A (zh) * 2014-09-05 2018-02-16 马恒标 大蒜中提取得到的抗肿瘤活性的多肽
US20170226157A1 (en) * 2014-12-09 2017-08-10 Biokine Therapeutics Ltd. Compositions and methods for the treatment of ocular diseases
WO2017009842A2 (en) 2015-07-16 2017-01-19 Biokine Therapeutics Ltd. Compositions and methods for treating cancer
EP3390378B1 (en) 2015-12-17 2022-03-30 AlonBio Ltd. Small molecules against cancer
DK3390364T3 (da) 2015-12-17 2020-10-12 Biokine Therapeutics Ltd Små molekyler til hæmning af kemokinaktivitet og/eller cancercellevækst
US20170204154A1 (en) 2016-01-20 2017-07-20 Delinia, Inc. Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
BR112018016924A2 (pt) 2016-02-23 2019-01-02 Biokine Therapeutics Ltd método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma
CN112567053A (zh) * 2018-08-10 2021-03-26 潘泽尔纳疗法有限公司 重组核酸构建体
KR20200044321A (ko) * 2018-10-19 2020-04-29 아이진 주식회사 염증성 질환의 예방 또는 치료용 약학적 조성물
IL288144B2 (en) 2019-05-15 2024-03-01 Alonbio Ltd Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death
KR102736939B1 (ko) * 2021-09-30 2024-12-03 (주)케어젠 항염증 활성을 갖는 펩타이드 및 이의 용도
KR102609822B1 (ko) * 2021-10-05 2023-12-06 (주)케어젠 항염증 활성을 갖는 펩타이드와 이의 용도

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US8685398B2 (en) 2014-04-01
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US9493557B2 (en) 2016-11-15
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