JP5775252B2 - 蛍光検出のための励起および結像光学素子 - Google Patents
蛍光検出のための励起および結像光学素子 Download PDFInfo
- Publication number
- JP5775252B2 JP5775252B2 JP2009171569A JP2009171569A JP5775252B2 JP 5775252 B2 JP5775252 B2 JP 5775252B2 JP 2009171569 A JP2009171569 A JP 2009171569A JP 2009171569 A JP2009171569 A JP 2009171569A JP 5775252 B2 JP5775252 B2 JP 5775252B2
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- JP
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- lens array
- array
- field lens
- pupil
- optical
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Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
- G02B27/0018—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 with means for preventing ghost images
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B3/00—Simple or compound lenses
- G02B3/0006—Arrays
- G02B3/0037—Arrays characterized by the distribution or form of lenses
- G02B3/0056—Arrays characterized by the distribution or form of lenses arranged along two different directions in a plane, e.g. honeycomb arrangement of lenses
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B3/00—Simple or compound lenses
- G02B3/0006—Arrays
- G02B3/0037—Arrays characterized by the distribution or form of lenses
- G02B3/0062—Stacked lens arrays, i.e. refractive surfaces arranged in at least two planes, without structurally separate optical elements in-between
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B2207/00—Coding scheme for general features or characteristics of optical elements and systems of subclass G02B, but not including elements and systems which would be classified in G02B6/00 and subgroups
- G02B2207/113—Fluorescence
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08013392A EP2148187A1 (de) | 2008-07-25 | 2008-07-25 | Anregungs- und Abbildungsoptik für die Fluoreszenzdetektion |
| EP08013392.9 | 2008-07-25 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010032513A JP2010032513A (ja) | 2010-02-12 |
| JP2010032513A5 JP2010032513A5 (enExample) | 2012-07-12 |
| JP5775252B2 true JP5775252B2 (ja) | 2015-09-09 |
Family
ID=39850802
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009171569A Active JP5775252B2 (ja) | 2008-07-25 | 2009-07-22 | 蛍光検出のための励起および結像光学素子 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US7906767B2 (enExample) |
| EP (2) | EP2148187A1 (enExample) |
| JP (1) | JP5775252B2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3907496A1 (en) * | 2020-05-07 | 2021-11-10 | Wistron Corporation | Detection device and detection method |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE212010000039U1 (de) * | 2009-04-03 | 2012-02-02 | Helixis, Inc. | Geräte zum erhitzen biologischer proben |
| WO2011031377A1 (en) * | 2009-09-09 | 2011-03-17 | Helixis, Inc. | Optical system for multiple reactions |
| DE102011055294B4 (de) | 2011-11-11 | 2013-11-07 | Leica Microsystems Cms Gmbh | Mikroskopische Einrichtung und Verfahren zur dreidimensionalen Lokalisierung von punktförmigen Objekten in einer Probe |
| CN102517205B (zh) * | 2012-01-09 | 2013-04-17 | 青岛理工大学 | 一种基于dna扩增的热传递检测装置 |
| US9395303B2 (en) | 2012-03-12 | 2016-07-19 | Mitsubishi Rayon Co., Ltd. | Fluorescence detection device and fluorescence detection method |
| JP6189666B2 (ja) * | 2012-08-02 | 2017-08-30 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 配列光学 |
| DE102012018303A1 (de) * | 2012-09-14 | 2014-03-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Messgerät zur Lumineszenzmessung |
| US10504132B2 (en) | 2012-11-27 | 2019-12-10 | American Express Travel Related Services Company, Inc. | Dynamic rewards program |
| US10309947B2 (en) | 2013-02-27 | 2019-06-04 | Trace-Ability, Inc. | System and method for radiosynthesis, quality control and dose dispensing |
| US20140273181A1 (en) | 2013-03-15 | 2014-09-18 | Biofire Diagnostics, Inc. | Compact optical system for substantially simultaneous monitoring of samples in a sample array |
| JP6449591B2 (ja) | 2013-09-02 | 2019-01-09 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 生物学的液体の光測定装置 |
| MX392471B (es) | 2013-11-17 | 2025-03-24 | Quantum Si Inc | Sistema optico y chip de ensayo para sondear, detectar y analizar moleculas |
| US11002717B2 (en) | 2014-02-26 | 2021-05-11 | Trace-Ability, Inc. | Systems and methods for characterizing radioactive analytes |
| US10895563B2 (en) | 2014-02-26 | 2021-01-19 | Trace-Ability, Inc. | Palette-based systems for analyte characterization |
| DK3198284T3 (da) * | 2014-09-27 | 2022-05-09 | Trace Ability Inc | Paletbaserede systemer til analytkarakterisering |
| JP6456983B2 (ja) * | 2015-02-03 | 2019-01-23 | 株式会社日立ハイテクノロジーズ | 多色検出装置 |
| ES2943159T3 (es) * | 2015-02-06 | 2023-06-09 | Life Technologies Corp | Instrumento óptico para análisis biológico |
| US10724947B2 (en) * | 2015-04-14 | 2020-07-28 | Cognex Corporation | System and method for acquiring images of surface texture |
| JP1565699S (enExample) * | 2016-01-12 | 2016-12-19 | ||
| DE102016115607A1 (de) | 2016-08-23 | 2018-03-01 | B. Braun Melsungen Ag | Messsystem mit verringertem Übersprechen zur Messung von Fluidparametern |
| EP3290119B1 (en) | 2016-09-01 | 2019-06-26 | Roche Diagniostics GmbH | Assembly, instrument for performing a temperature-dependent reaction and method for performing a temperature-dependent reaction in an assembly |
| TWI614154B (zh) * | 2017-03-22 | 2018-02-11 | 智慧型光源控制系統 | |
| CN107389671A (zh) * | 2017-07-05 | 2017-11-24 | 江苏大学 | 一种可视化味觉、嗅觉融合传感器的制作方法 |
| WO2019143558A1 (en) | 2018-01-22 | 2019-07-25 | Verily Life Sciences Llc | High-throughput hyperspectral imaging systems |
| CN110184175A (zh) * | 2018-02-22 | 2019-08-30 | 致茂电子(苏州)有限公司 | 自动化荧光检测系统 |
| EP3803397A2 (en) * | 2018-05-25 | 2021-04-14 | Five Prime Therapeutics, Inc. | Enhanced cytometry for tissue characterization and screening |
| EP3812741B1 (en) * | 2018-06-22 | 2024-09-11 | Hitachi High-Tech Corporation | Electrophoresis apparatus |
| JP7228060B2 (ja) * | 2018-06-22 | 2023-02-22 | 株式会社日立ハイテク | 電気泳動装置 |
| KR102541847B1 (ko) * | 2018-07-27 | 2023-06-14 | 스카이버스 테크놀로지 씨오., 엘티디. | 발광 장치, 광학 검출 시스템, 광학 검출 장치 및 광학 검출 방법 |
| CN110372761B (zh) * | 2019-08-22 | 2024-04-12 | 北京擎科生物科技股份有限公司 | 一种无气味扩散且结构紧凑的dna合成仪 |
| KR102292599B1 (ko) * | 2019-11-06 | 2021-08-23 | 주식회사 뷰웍스 | 광학 분석 장치 및 광학 분석 방법 |
| DE102020108432A1 (de) | 2020-03-25 | 2021-09-30 | Jenoptik Optical Systems Gmbh | Vorrichtung und Verfahren zur Lumineszenzanalyse mehrerer Proben |
| US12209964B2 (en) * | 2020-10-15 | 2025-01-28 | Visera Technologies Company Limited | Bio-chip, bio-detection system and bio-detection method |
| CN114594449B (zh) * | 2020-12-04 | 2025-09-30 | 上海禾赛科技有限公司 | 探测装置、探测方法和激光雷达 |
| JP7696755B2 (ja) * | 2021-05-25 | 2025-06-23 | 株式会社エビデント | 観察装置 |
| CN115046479B (zh) * | 2022-08-12 | 2022-11-08 | 杭州纳境科技有限公司 | 超透镜检测装置及系统 |
| EP4575467A1 (en) | 2023-12-22 | 2025-06-25 | F. Hoffmann-La Roche AG | Techniques for illumination and detection in analytical analyzers |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01233345A (ja) * | 1988-03-14 | 1989-09-19 | Koden Electron Co Ltd | 光学式分析計 |
| US5118801A (en) | 1988-09-30 | 1992-06-02 | The Public Health Research Institute | Nucleic acid process containing improved molecular switch |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| ATE390491T1 (de) | 1996-06-04 | 2008-04-15 | Univ Utah Res Found | Behälter zum durchführen und beobachten biologischer prozesse |
| AU726501B2 (en) | 1996-06-04 | 2000-11-09 | University Of Utah Research Foundation | Monitoring hybridization during PCR |
| CN100356163C (zh) | 1996-08-16 | 2007-12-19 | Ge保健尼亚加拉公司 | 用于分析井板、凝胶和斑点的数字成像系统 |
| DE19748211A1 (de) * | 1997-10-31 | 1999-05-06 | Zeiss Carl Fa | Optisches Array-System und Reader für Mikrotiterplatten |
| US6818437B1 (en) * | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
| EP1978351B1 (en) | 1998-05-16 | 2011-11-30 | Life Technologies Corporation | Instrument for monitoring polymerase chain reaction of dna |
| JP2000074837A (ja) | 1998-08-31 | 2000-03-14 | Fuji Photo Film Co Ltd | 撮影装置 |
| FI982005L (fi) | 1998-09-17 | 2000-03-18 | Wallac Oy | Näytteiden kuvantamislaite |
| DE19919092A1 (de) * | 1999-04-27 | 2000-11-02 | Zeiss Carl Jena Gmbh | Anordnung zur optischen Auswertung eines Gegenstandsarrays |
| US7387891B2 (en) * | 1999-05-17 | 2008-06-17 | Applera Corporation | Optical instrument including excitation source |
| US20020005493A1 (en) | 2000-04-04 | 2002-01-17 | Reese Steven A. | Optical components for microarray analysis |
| DE10017824B4 (de) * | 2000-04-10 | 2004-03-18 | Till I.D. Gmbh | Vorrichtung zur parallelen photometrischen Fluoreszenz- oder Lumineszenzanalyse mehrerer voneinander getrennter Probenbereiche auf einem Objekt |
| JP2002014044A (ja) | 2000-06-29 | 2002-01-18 | Nikon Corp | 蛍光測定装置 |
| US20030160957A1 (en) * | 2000-07-14 | 2003-08-28 | Applera Corporation | Scanning system and method for scanning a plurality of samples |
| US6635427B2 (en) | 2000-08-11 | 2003-10-21 | University Of Utah Research Foundation | Single-labeled oligonucleotide probes for homogeneous nucleic acid sequence analysis |
| US20060291048A1 (en) * | 2001-03-19 | 2006-12-28 | Dmetrix, Inc. | Multi-axis imaging system with single-axis relay |
| US6650411B2 (en) | 2001-04-26 | 2003-11-18 | Affymetrix, Inc. | System, method, and product for pixel clocking in scanning of biological materials |
| JP4834242B2 (ja) | 2001-05-30 | 2011-12-14 | オリンパス株式会社 | 蛍光読み取り装置 |
| DE10131687A1 (de) | 2001-06-29 | 2003-01-16 | Eppendorf Ag | Vorrichtung zur Durchführung von Nukleinsäure-Amplifikationsreaktionen bei gleichzeitiger Verfolgung der Bildung von Amplifikationsprodukten |
| JP3999479B2 (ja) | 2001-07-10 | 2007-10-31 | オリンパス株式会社 | 光学装置 |
| JP2003028797A (ja) | 2001-07-11 | 2003-01-29 | Hitachi Software Eng Co Ltd | 蛍光読み取り装置 |
| DE10155142C2 (de) | 2001-11-12 | 2003-09-04 | Friz Biochem Gmbh | Dunkelfeld-Abbildungsvorrichtung zur ortsaufgelösten Dunkelfeldabbildung einer flächigen Probe |
| DE10200499A1 (de) | 2002-01-03 | 2003-07-10 | Zeiss Carl Jena Gmbh | Verfahren und/oder Anordnung zur Identifikation von fluoreszierenden, lumineszierenden und/oder absorbierenden Substanzen auf und/oder in Probenträgern |
| DE10206004A1 (de) | 2002-02-14 | 2003-08-28 | Zeiss Carl Jena Gmbh | Vorrichtung zur konfokalen optischen Mikroanalyse |
| AU2003243281A1 (en) * | 2002-05-17 | 2003-12-02 | Applera Corporation | Optical instrument includung excitation source |
| JP4155767B2 (ja) * | 2002-07-05 | 2008-09-24 | 美和ロック株式会社 | ドア用錠受け金具 |
| ATE357653T1 (de) | 2005-01-18 | 2007-04-15 | Hoffmann La Roche | Fluoreszenzabbildung mittels telezentrischer anregungs- und abbildungsoptiken |
| ES2285578T3 (es) * | 2005-01-18 | 2007-11-16 | F. Hoffmann-La Roche Ag | Visualizacion de señales de fluorescencia utilizando telecentricidad. |
| WO2009156942A1 (en) * | 2008-06-24 | 2009-12-30 | Koninklijke Philips Electronics N.V. | Microarray characterization system and method |
-
2008
- 2008-07-25 EP EP08013392A patent/EP2148187A1/de not_active Withdrawn
-
2009
- 2009-07-17 EP EP09100361.6A patent/EP2148188B1/en active Active
- 2009-07-21 US US12/506,792 patent/US7906767B2/en active Active
- 2009-07-22 JP JP2009171569A patent/JP5775252B2/ja active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3907496A1 (en) * | 2020-05-07 | 2021-11-10 | Wistron Corporation | Detection device and detection method |
| US11892407B2 (en) | 2020-05-07 | 2024-02-06 | Wistron Corporation | Detection device and detection method |
Also Published As
| Publication number | Publication date |
|---|---|
| US7906767B2 (en) | 2011-03-15 |
| US20100019157A1 (en) | 2010-01-28 |
| EP2148188B1 (en) | 2014-01-08 |
| JP2010032513A (ja) | 2010-02-12 |
| EP2148187A1 (de) | 2010-01-27 |
| EP2148188A1 (en) | 2010-01-27 |
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