JP5756125B2 - 妊娠高血圧腎症の危険性の検出 - Google Patents

妊娠高血圧腎症の危険性の検出 Download PDF

Info

Publication number
JP5756125B2
JP5756125B2 JP2012545311A JP2012545311A JP5756125B2 JP 5756125 B2 JP5756125 B2 JP 5756125B2 JP 2012545311 A JP2012545311 A JP 2012545311A JP 2012545311 A JP2012545311 A JP 2012545311A JP 5756125 B2 JP5756125 B2 JP 5756125B2
Authority
JP
Japan
Prior art keywords
abundance
preeclampsia
risk
acid
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2012545311A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013515255A (ja
Inventor
ケニー ルイーズ
ケニー ルイーズ
ニュートン ベイカー フィリップ
ニュートン ベイカー フィリップ
ブロードハースト デービッド
ブロードハースト デービッド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College Cork
Original Assignee
University College Cork
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University College Cork filed Critical University College Cork
Publication of JP2013515255A publication Critical patent/JP2013515255A/ja
Application granted granted Critical
Publication of JP5756125B2 publication Critical patent/JP5756125B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Artificial Intelligence (AREA)
  • Software Systems (AREA)
  • Evolutionary Computation (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioethics (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
JP2012545311A 2009-12-21 2010-12-21 妊娠高血圧腎症の危険性の検出 Expired - Fee Related JP5756125B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28846509P 2009-12-21 2009-12-21
US61/288,465 2009-12-21
PCT/EP2010/070446 WO2011080170A1 (en) 2009-12-21 2010-12-21 Detection of risk of pre-eclampsia

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014235001A Division JP5815830B2 (ja) 2009-12-21 2014-11-19 妊娠高血圧腎症の危険性の検出

Publications (2)

Publication Number Publication Date
JP2013515255A JP2013515255A (ja) 2013-05-02
JP5756125B2 true JP5756125B2 (ja) 2015-07-29

Family

ID=43587630

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2012545311A Expired - Fee Related JP5756125B2 (ja) 2009-12-21 2010-12-21 妊娠高血圧腎症の危険性の検出
JP2014235001A Active JP5815830B2 (ja) 2009-12-21 2014-11-19 妊娠高血圧腎症の危険性の検出
JP2015187177A Expired - Fee Related JP6185532B2 (ja) 2009-12-21 2015-09-24 妊娠高血圧腎症の危険性の検出

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2014235001A Active JP5815830B2 (ja) 2009-12-21 2014-11-19 妊娠高血圧腎症の危険性の検出
JP2015187177A Expired - Fee Related JP6185532B2 (ja) 2009-12-21 2015-09-24 妊娠高血圧腎症の危険性の検出

Country Status (8)

Country Link
US (3) US9262582B2 (https=)
EP (3) EP3422006B1 (https=)
JP (3) JP5756125B2 (https=)
CN (1) CN102893156A (https=)
BR (1) BR112012016918A2 (https=)
ES (1) ES2970328T3 (https=)
RU (1) RU2012131290A (https=)
WO (2) WO2011080170A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200097651A (ko) * 2019-02-08 2020-08-19 서울대학교산학협력단 전신 홍반 루푸스 산모의 임신 위험도를 평가하는 방법

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102893156A (zh) * 2009-12-21 2013-01-23 爱尔兰国立科克大学 子痫前期风险的检测
CN103957813B (zh) * 2011-11-30 2016-08-17 皇家飞利浦有限公司 用于识别高危妊娠的系统和方法
EP2836832A4 (en) * 2012-04-13 2015-10-14 Univ Wayne State EARLY TRIMESTER SCREENING FOR EARLY AND LATE MANIFESTED PREAMBLE LAMPSY
WO2014001244A1 (en) * 2012-06-27 2014-01-03 Roche Diagnostics Gmbh MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD
CN103513042A (zh) * 2013-09-23 2014-01-15 中国科学院动物研究所 用于预测或早期诊断妊娠高血压疾病的试剂盒
US20170205420A1 (en) * 2014-06-23 2017-07-20 Wallac Oy Biochemical markers for use in determining risk of diabetes
RU2558465C1 (ru) * 2014-07-15 2015-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования Читинская государственная медицинская академия Министерства здравоохранения РФ Способ доклинической диагностики преэклампсии
JP2017535750A (ja) * 2014-09-24 2017-11-30 マップ アイピー ホールディング リミテッド 妊娠の予後を提供する方法
WO2016149759A1 (en) * 2015-03-23 2016-09-29 Adelaide Research & Innovation Pty Ltd Methods and systems for determining risk of a pregnancy complication occurring
WO2017075027A1 (en) * 2015-10-26 2017-05-04 Brigham Young University Serum lipid biomarkers of preeclampsia
GB201600882D0 (en) 2016-01-18 2016-03-02 Power Box Ag Improvements to router apparatus
WO2017180876A1 (en) * 2016-04-13 2017-10-19 Abbott Laboratories Cardiac troponin i detection during pregnancy for cardiovascular disease identification and risk assessment
US10978202B2 (en) * 2016-04-21 2021-04-13 Perigen Inc. Method and system for concurrently monitoring multiple obstetrics patients
US11682495B2 (en) * 2016-10-13 2023-06-20 Carnegie Mellon University Structured medical data classification system for monitoring and remediating treatment risks
RU2638785C1 (ru) * 2016-12-12 2017-12-15 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ прогнозирования риска развития преэклампсии тяжелого течения
CN106755492B (zh) * 2017-01-24 2020-04-21 深圳金蕊科技有限公司 用于预测子痫前期的成套snp及其应用
WO2018174876A1 (en) * 2017-03-22 2018-09-27 Mprobe Inc. Methods and compositions for providing a preeclampsia assessment with metabolites
JP2018175850A (ja) * 2017-04-14 2018-11-15 株式会社Ｎｔｔドコモ データ収集装置及びデータ収集方法
JP2019041754A (ja) * 2017-08-31 2019-03-22 株式会社Ｎｔｔドコモ 予測装置及び予測方法
US11341138B2 (en) * 2017-12-06 2022-05-24 International Business Machines Corporation Method and system for query performance prediction
ES3056147T3 (en) * 2018-02-09 2026-02-18 Metabolomic Diagnostics Ltd A system and method of generating a model to detect, or predict the risk of, an outcome
US20210033619A1 (en) * 2018-02-09 2021-02-04 Metabolomic Diagnostics Limited Methods of predicting pre term birth from preeclampsia using metabolic and protein biomarkers
GB201802123D0 (en) * 2018-02-09 2018-03-28 Metabolomic Diagnostics Ltd A method of processomg a biological sample
US20210275486A1 (en) * 2018-06-21 2021-09-09 Maruha Nichiro Corporation Renal function maintenance and protection agent, and method for evaluating effect thereof
JP7013416B2 (ja) * 2018-06-21 2022-01-31 マルハニチロ株式会社 腎機能維持及び保護剤、並びに、その効果評価方法
CN112673259B (zh) * 2018-07-20 2024-11-22 豪夫迈·罗氏有限公司 基于igfbp-7的先兆子痫预测
CA3127522A1 (en) * 2019-01-29 2020-08-06 Metabolomic Diagnostics Limited Detection of risk of pre-eclampsia in obese pregnant women
EP3999846A4 (en) 2019-07-25 2023-08-09 Overture Life, Inc IDENTIFICATION OF VIABLE HUMAN EMBRYO
CN110534184B (zh) * 2019-08-29 2022-07-15 中国人民解放军陆军军医大学第一附属医院 一种产科手术资源配置预测系统
CN110806456B (zh) * 2019-11-12 2022-03-15 浙江工业大学 一种UPLC-HRMS Profile模式非靶向代谢轮廓数据自动解析的方法
US20230132131A1 (en) * 2020-02-28 2023-04-27 Metabolomic Diagnostics Limited Prediction of risk of pre-eclampsia
CN112820406A (zh) * 2020-12-30 2021-05-18 复旦大学附属妇产科医院 一种妊娠早期对子痫前期发病风险的预测方法
CN113092777B (zh) * 2021-03-26 2023-11-14 泰达国际心血管病医院 孕早期进行重症子痫前期患者筛查的方法
KR102366856B1 (ko) * 2021-04-23 2022-02-23 이화여자대학교 산학협력단 레티노이드 대사체를 이용한 조산의 조기 예측 방법
CN117233367B (zh) * 2023-11-16 2024-02-09 哈尔滨脉图精准技术有限公司 妊娠期高血压风险评估的代谢标志物
CN118518860B (zh) * 2024-04-16 2025-06-10 山东第一医科大学(山东省医学科学院) 用于诊断或预警急性冠脉综合征的生物标志物及其筛选方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030068653A1 (en) * 2000-06-01 2003-04-10 Parrott Jeff A. Determining existence of complications in pregnancies by measuring levels of bioactive lipids
DE10043124A1 (de) * 2000-08-31 2002-03-14 Max Delbrueck Centrum Verfahren zur Diagnostik von neuronalen Erkrankungen sowie zur Behandlung der defizienten primären Hämostase
WO2006086731A2 (en) * 2005-02-09 2006-08-17 The Gov't.T Of The Usa As Represented By The Secretary Of The Department Of Health & Human Services Method for identifying the risk of preterm delivery
US20080255764A1 (en) * 2005-09-12 2008-10-16 Phenomenome Discoveries Inc. Methods for the Diagnosis of Colorectal Cancer and Ovarian Cancer by the Measurement of Vitamin E-Related Metabolites
EP1996923B1 (en) * 2006-03-02 2012-06-27 PerkinElmer Health Sciences, Inc. Methods for distinguishing isomers using mass spectrometry
GB0612669D0 (en) * 2006-06-27 2006-08-09 Univ Leeds Biomarkers for preeclampsia
GB0613165D0 (en) * 2006-06-28 2006-08-09 Univ Warwick Real-time infrared measurement and imaging system
US20080071151A1 (en) * 2006-06-30 2008-03-20 Sogin David C Method and Apparatus for Diagnosing Pre-eclampsia
CN101122600A (zh) * 2007-08-16 2008-02-13 复旦大学附属中山医院 一种血清小分子代谢产物的检测方法
CN102893156A (zh) * 2009-12-21 2013-01-23 爱尔兰国立科克大学 子痫前期风险的检测

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200097651A (ko) * 2019-02-08 2020-08-19 서울대학교산학협력단 전신 홍반 루푸스 산모의 임신 위험도를 평가하는 방법
KR102308865B1 (ko) 2019-02-08 2021-10-05 서울대학교산학협력단 전신 홍반 루푸스 산모의 임신 위험도를 평가하는 방법

Also Published As

Publication number Publication date
EP3422006C0 (en) 2023-11-01
JP6185532B2 (ja) 2017-08-23
JP2016014685A (ja) 2016-01-28
CN102893156A (zh) 2013-01-23
EP2517019A1 (en) 2012-10-31
JP2013515255A (ja) 2013-05-02
JP2015038512A (ja) 2015-02-26
US20130073212A1 (en) 2013-03-21
WO2011080170A1 (en) 2011-07-07
US10564146B2 (en) 2020-02-18
JP5815830B2 (ja) 2015-11-17
EP3422006B1 (en) 2023-11-01
US20190056380A1 (en) 2019-02-21
US9262582B2 (en) 2016-02-16
ES2970328T3 (es) 2024-05-28
EP3206033A1 (en) 2017-08-16
WO2011080170A9 (en) 2012-07-12
US20160223517A1 (en) 2016-08-04
BR112012016918A2 (pt) 2016-04-12
WO2011075842A1 (en) 2011-06-30
EP3422006A1 (en) 2019-01-02
RU2012131290A (ru) 2014-01-27

Similar Documents

Publication Publication Date Title
JP6185532B2 (ja) 妊娠高血圧腎症の危険性の検出
CN113396332B (zh) 评价妊娠进展和早产流产以进行临床干预的方法及其应用
TWI610079B (zh) 用於診斷冠狀動脈粥樣硬化症之以血液為主的生物標記
US20150168419A1 (en) Prediction of a small-for-gestational age (sga) infant
Lizewska et al. Maternal plasma metabolomic profiles in spontaneous preterm birth: preliminary results
CN113009162A (zh) 一种用于妊娠期糖尿病诊断的血清代谢标志物及其应用
CN113008972B (zh) 用于妊娠期糖尿病诊断的血清代谢标志物及其应用
JP2024517685A (ja) レチノイドメタボロームを利用した早産の早期予測方法
Bahado-Singh et al. Metabolomic analysis for first-trimester trisomy 18 detection
Kalapouti et al. Lipidomic signatures in maternal blood and placenta: Systematic evidence linking lipid profiles to pregnancy outcomes and fetal growth
US20150185238A1 (en) Novel method for the diagnosis of endometriosis
US10835148B2 (en) Metabolomic prediction of congenital heart defect during pregnancy, newborn and pediatric stages
FI129851B (en) Biomarkers
Wang et al. Metabolic Signature of Gestational Diabetes Mellitus and Risk of Adverse Birth Outcomes: A Prospective Birth Cohort Study
CN120352529A (zh) 用于预测早期心肌梗死的生物标志物及其应用
WO2022099320A1 (en) Systems and methods for gestational age dating and applications thereof
Class et al. Patent application title: PREDICTION OF A SMALL-FOR-GESTATIONAL AGE (SGA) INFANT Inventors: Louise Kenny (Co. Cork, IE) Philip Baker (Auckland, NZ) Assignees: UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20131210

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20140716

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140819

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20141119

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150428

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150528

R150 Certificate of patent or registration of utility model

Ref document number: 5756125

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees