CN102893156A - 子痫前期风险的检测 - Google Patents

子痫前期风险的检测 Download PDF

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Publication number
CN102893156A
CN102893156A CN2010800637749A CN201080063774A CN102893156A CN 102893156 A CN102893156 A CN 102893156A CN 2010800637749 A CN2010800637749 A CN 2010800637749A CN 201080063774 A CN201080063774 A CN 201080063774A CN 102893156 A CN102893156 A CN 102893156A
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acid
abundance
preeclampsia
risk
metabolite
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Chinese (zh)
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L·肯尼
P·牛顿贝克
D·布洛德赫斯特
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University College Cork
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University College Cork
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00—Subject matter not provided for in other groups of this subclass
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

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  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
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  • Hematology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
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CN2010800637749A 2009-12-21 2010-12-21 子痫前期风险的检测 Pending CN102893156A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28846509P 2009-12-21 2009-12-21
US61/288,465 2009-12-21
PCT/EP2010/070446 WO2011080170A1 (en) 2009-12-21 2010-12-21 Detection of risk of pre-eclampsia

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CN102893156A true CN102893156A (zh) 2013-01-23

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CN2010800637749A Pending CN102893156A (zh) 2009-12-21 2010-12-21 子痫前期风险的检测

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US (3) US9262582B2 (https=)
EP (3) EP3422006B1 (https=)
JP (3) JP5756125B2 (https=)
CN (1) CN102893156A (https=)
BR (1) BR112012016918A2 (https=)
ES (1) ES2970328T3 (https=)
RU (1) RU2012131290A (https=)
WO (2) WO2011080170A1 (https=)

Cited By (12)

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WO2015039419A1 (zh) * 2013-09-23 2015-03-26 中国科学院动物研究所 用于预测或早期诊断妊娠高血压疾病的试剂盒
CN106574932A (zh) * 2014-06-23 2017-04-19 沃拉克有限公司 用于在测定糖尿病风险的生化标志
CN106755492A (zh) * 2017-01-24 2017-05-31 深圳金蕊科技有限公司 用于预测子痫前期的成套snp及其应用
CN107003319A (zh) * 2014-09-24 2017-08-01 曼普知识产权控股有限公司 提供妊娠预测的方法
CN109844540A (zh) * 2016-04-13 2019-06-04 雅培制药有限公司 怀孕期间用于心血管疾病鉴定和风险评价的心肌肌钙蛋白i检测
CN110534184A (zh) * 2019-08-29 2019-12-03 中国人民解放军陆军军医大学第一附属医院 一种产科手术资源配置预测系统
CN110806456A (zh) * 2019-11-12 2020-02-18 浙江工业大学 一种UPLC-HRMS Profile模式非靶向代谢轮廓数据自动解析的方法
CN112105931A (zh) * 2018-02-09 2020-12-18 代谢组学诊断有限公司 用代谢生物标记物和蛋白质生物标记物预测子痫前期早产的方法
CN112820406A (zh) * 2020-12-30 2021-05-18 复旦大学附属妇产科医院 一种妊娠早期对子痫前期发病风险的预测方法
CN113092777A (zh) * 2021-03-26 2021-07-09 泰达国际心血管病医院 孕早期进行重症子痫前期患者筛查的方法
CN113748344A (zh) * 2019-01-29 2021-12-03 代谢组学诊断有限公司 肥胖孕妇先兆子痫风险的检测
CN118518860A (zh) * 2024-04-16 2024-08-20 山东第一医科大学(山东省医学科学院) 用于诊断或预警急性冠脉综合征的生物标志物及其筛选方法和应用

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CN102893156A (zh) * 2009-12-21 2013-01-23 爱尔兰国立科克大学 子痫前期风险的检测
CN103957813B (zh) * 2011-11-30 2016-08-17 皇家飞利浦有限公司 用于识别高危妊娠的系统和方法
EP2836832A4 (en) * 2012-04-13 2015-10-14 Univ Wayne State EARLY TRIMESTER SCREENING FOR EARLY AND LATE MANIFESTED PREAMBLE LAMPSY
WO2014001244A1 (en) * 2012-06-27 2014-01-03 Roche Diagnostics Gmbh MEANS AND METHODS APPLYING sFlt-1/PlGF OR ENDOGLIN/PlGF RATIO TO RULE-OUT ONSET OF PREECLAMPSIA WITHIN A CERTAIN TIME PERIOD
RU2558465C1 (ru) * 2014-07-15 2015-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования Читинская государственная медицинская академия Министерства здравоохранения РФ Способ доклинической диагностики преэклампсии
WO2016149759A1 (en) * 2015-03-23 2016-09-29 Adelaide Research & Innovation Pty Ltd Methods and systems for determining risk of a pregnancy complication occurring
WO2017075027A1 (en) * 2015-10-26 2017-05-04 Brigham Young University Serum lipid biomarkers of preeclampsia
GB201600882D0 (en) 2016-01-18 2016-03-02 Power Box Ag Improvements to router apparatus
US10978202B2 (en) * 2016-04-21 2021-04-13 Perigen Inc. Method and system for concurrently monitoring multiple obstetrics patients
US11682495B2 (en) * 2016-10-13 2023-06-20 Carnegie Mellon University Structured medical data classification system for monitoring and remediating treatment risks
RU2638785C1 (ru) * 2016-12-12 2017-12-15 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ прогнозирования риска развития преэклампсии тяжелого течения
WO2018174876A1 (en) * 2017-03-22 2018-09-27 Mprobe Inc. Methods and compositions for providing a preeclampsia assessment with metabolites
JP2018175850A (ja) * 2017-04-14 2018-11-15 株式会社Ｎｔｔドコモ データ収集装置及びデータ収集方法
JP2019041754A (ja) * 2017-08-31 2019-03-22 株式会社Ｎｔｔドコモ 予測装置及び予測方法
US11341138B2 (en) * 2017-12-06 2022-05-24 International Business Machines Corporation Method and system for query performance prediction
ES3056147T3 (en) * 2018-02-09 2026-02-18 Metabolomic Diagnostics Ltd A system and method of generating a model to detect, or predict the risk of, an outcome
GB201802123D0 (en) * 2018-02-09 2018-03-28 Metabolomic Diagnostics Ltd A method of processomg a biological sample
US20210275486A1 (en) * 2018-06-21 2021-09-09 Maruha Nichiro Corporation Renal function maintenance and protection agent, and method for evaluating effect thereof
JP7013416B2 (ja) * 2018-06-21 2022-01-31 マルハニチロ株式会社 腎機能維持及び保護剤、並びに、その効果評価方法
CN112673259B (zh) * 2018-07-20 2024-11-22 豪夫迈·罗氏有限公司 基于igfbp-7的先兆子痫预测
KR102308865B1 (ko) * 2019-02-08 2021-10-05 서울대학교산학협력단 전신 홍반 루푸스 산모의 임신 위험도를 평가하는 방법
EP3999846A4 (en) 2019-07-25 2023-08-09 Overture Life, Inc IDENTIFICATION OF VIABLE HUMAN EMBRYO
US20230132131A1 (en) * 2020-02-28 2023-04-27 Metabolomic Diagnostics Limited Prediction of risk of pre-eclampsia
KR102366856B1 (ko) * 2021-04-23 2022-02-23 이화여자대학교 산학협력단 레티노이드 대사체를 이용한 조산의 조기 예측 방법
CN117233367B (zh) * 2023-11-16 2024-02-09 哈尔滨脉图精准技术有限公司 妊娠期高血压风险评估的代谢标志物

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015039419A1 (zh) * 2013-09-23 2015-03-26 中国科学院动物研究所 用于预测或早期诊断妊娠高血压疾病的试剂盒
CN106574932A (zh) * 2014-06-23 2017-04-19 沃拉克有限公司 用于在测定糖尿病风险的生化标志
CN107003319B (zh) * 2014-09-24 2019-12-31 曼普知识产权控股有限公司 提供妊娠预测的方法
CN107003319A (zh) * 2014-09-24 2017-08-01 曼普知识产权控股有限公司 提供妊娠预测的方法
CN109844540A (zh) * 2016-04-13 2019-06-04 雅培制药有限公司 怀孕期间用于心血管疾病鉴定和风险评价的心肌肌钙蛋白i检测
CN106755492A (zh) * 2017-01-24 2017-05-31 深圳金蕊科技有限公司 用于预测子痫前期的成套snp及其应用
CN112105931A (zh) * 2018-02-09 2020-12-18 代谢组学诊断有限公司 用代谢生物标记物和蛋白质生物标记物预测子痫前期早产的方法
CN113748344A (zh) * 2019-01-29 2021-12-03 代谢组学诊断有限公司 肥胖孕妇先兆子痫风险的检测
CN110534184A (zh) * 2019-08-29 2019-12-03 中国人民解放军陆军军医大学第一附属医院 一种产科手术资源配置预测系统
CN110534184B (zh) * 2019-08-29 2022-07-15 中国人民解放军陆军军医大学第一附属医院 一种产科手术资源配置预测系统
CN110806456A (zh) * 2019-11-12 2020-02-18 浙江工业大学 一种UPLC-HRMS Profile模式非靶向代谢轮廓数据自动解析的方法
CN110806456B (zh) * 2019-11-12 2022-03-15 浙江工业大学 一种UPLC-HRMS Profile模式非靶向代谢轮廓数据自动解析的方法
CN112820406A (zh) * 2020-12-30 2021-05-18 复旦大学附属妇产科医院 一种妊娠早期对子痫前期发病风险的预测方法
CN113092777A (zh) * 2021-03-26 2021-07-09 泰达国际心血管病医院 孕早期进行重症子痫前期患者筛查的方法
CN113092777B (zh) * 2021-03-26 2023-11-14 泰达国际心血管病医院 孕早期进行重症子痫前期患者筛查的方法
CN118518860A (zh) * 2024-04-16 2024-08-20 山东第一医科大学(山东省医学科学院) 用于诊断或预警急性冠脉综合征的生物标志物及其筛选方法和应用
CN118518860B (zh) * 2024-04-16 2025-06-10 山东第一医科大学(山东省医学科学院) 用于诊断或预警急性冠脉综合征的生物标志物及其筛选方法和应用

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EP3422006C0 (en) 2023-11-01
JP6185532B2 (ja) 2017-08-23
JP2016014685A (ja) 2016-01-28
EP2517019A1 (en) 2012-10-31
JP2013515255A (ja) 2013-05-02
JP2015038512A (ja) 2015-02-26
US20130073212A1 (en) 2013-03-21
WO2011080170A1 (en) 2011-07-07
US10564146B2 (en) 2020-02-18
JP5815830B2 (ja) 2015-11-17
EP3422006B1 (en) 2023-11-01
US20190056380A1 (en) 2019-02-21
US9262582B2 (en) 2016-02-16
ES2970328T3 (es) 2024-05-28
EP3206033A1 (en) 2017-08-16
WO2011080170A9 (en) 2012-07-12
US20160223517A1 (en) 2016-08-04
JP5756125B2 (ja) 2015-07-29
BR112012016918A2 (pt) 2016-04-12
WO2011075842A1 (en) 2011-06-30
EP3422006A1 (en) 2019-01-02
RU2012131290A (ru) 2014-01-27

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