JP5715241B2 - 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 - Google Patents

新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 Download PDF

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JP5715241B2
JP5715241B2 JP2013510364A JP2013510364A JP5715241B2 JP 5715241 B2 JP5715241 B2 JP 5715241B2 JP 2013510364 A JP2013510364 A JP 2013510364A JP 2013510364 A JP2013510364 A JP 2013510364A JP 5715241 B2 JP5715241 B2 JP 5715241B2
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compound
brd4
cell
certain embodiments
optionally substituted
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Japanese (ja)
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JP2013532130A5 (enExample
JP2013532130A (ja
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ブラドナー，ジェームズ，エリオット
チー，チュン
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Dana Farber Cancer Institute Inc
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Dana Farber Cancer Institute Inc
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Priority claimed from PCT/US2011/036701 external-priority patent/WO2011143669A2/en
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2013510364A 2010-05-14 2011-05-16 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法 Active JP5715241B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US33499110P 2010-05-14 2010-05-14
US61/334,991 2010-05-14
US37074510P 2010-08-04 2010-08-04
US61/370,745 2010-08-04
US37586310P 2010-08-22 2010-08-22
US61/375,863 2010-08-22
PCT/US2011/036701 WO2011143669A2 (en) 2010-05-14 2011-05-16 Compositions and methods for treating neoplasia, inflammatory disease and other disorders

Related Child Applications (1)

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JP2015049960A Division JP5937247B2 (ja) 2010-05-14 2015-03-12 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法

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JP2013532130A JP2013532130A (ja) 2013-08-15
JP2013532130A5 JP2013532130A5 (enExample) 2014-11-06
JP5715241B2 true JP5715241B2 (ja) 2015-05-07

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JP2013510364A Active JP5715241B2 (ja) 2010-05-14 2011-05-16 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法
JP2015049960A Active JP5937247B2 (ja) 2010-05-14 2015-03-12 新生物、炎症性疾患、およびその他の障害を治療するための組成物および方法

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Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3182721B2 (ja) 1997-08-06 2001-07-03 理兆 上田 自動車のペダル装置
WO2011143651A1 (en) * 2010-05-14 2011-11-17 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating metabolism
US8981083B2 (en) 2010-05-14 2015-03-17 Dana Farber Cancer Institute, Inc. Compositions and methods for treating neoplasia, inflammatory disease and other disorders
BR112014032105A2 (pt) * 2012-06-25 2017-08-01 Oncoethix Sa método para o tratamento de câncer
WO2015018521A1 (en) * 2013-08-06 2015-02-12 Oncoethix Sa Method of treating diffuse large b-cell lymphoma (dlbcl) using a bet-bromodomain inhibitor
WO2015070020A2 (en) * 2013-11-08 2015-05-14 Dana-Farber Cancer Institute, Inc. Combination therapy for cancer using bromodomain and extra-terminal (bet) protein inhibitors
RU2722179C2 (ru) 2014-02-28 2020-05-28 Тэнша Терапеутикс, Инк. Лечение состояний, ассоциированных с гиперинсулинемией
MX2017016337A (es) * 2015-06-26 2018-11-22 Tensha Therapeutics Inc Tratamiento de carcinoma de linea media nut.
BR112018004618A2 (pt) * 2015-09-11 2018-09-25 Dana-Farber Cancer Institute, Inc. ciano tienotriazoldiazepinas e usos das mesmas
CA2996977A1 (en) 2015-09-11 2017-03-16 Dana-Farber Cancer Institute, Inc. Acetamide thienotriazolodiazepines and uses thereof
EP3355922A2 (en) * 2015-10-02 2018-08-08 Dana Farber Cancer Institute, Inc. Combination therapy of bromodomain inhibitors and checkpoint blockade
CA3014644A1 (en) * 2016-02-15 2017-08-24 The Regents Of The University Of Michigan Fused 1,4-oxazepines and related analogs as bet bromodomain inhibitors
WO2018109053A1 (en) * 2016-12-16 2018-06-21 F. Hoffmann-La Roche Ag Process for the manufacture of diazepine derivatives
CN109503618A (zh) * 2017-09-14 2019-03-22 成都海创药业有限公司 一种brd4抑制剂
EP3806860A1 (en) * 2018-06-13 2021-04-21 Dybly AG Preparation of condensed triazepine derivatives and their use as bet inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL127516A0 (en) * 1996-06-12 1999-10-28 Japan Tobacco Inc A cytokine production inhibitor
US7589167B2 (en) * 2000-02-22 2009-09-15 J. David Gladstone Institutes ZA loops of bromodomains
JP2006519236A (ja) * 2003-02-27 2006-08-24 アボット・ラボラトリーズ 複素環式キナーゼ阻害剤
EP2239264A4 (en) * 2007-12-28 2012-01-11 Mitsubishi Tanabe Pharma Corp ANTITUMORAL MEDIUM
ES2654423T3 (es) * 2009-11-05 2018-02-13 Glaxosmithkline Llc Inhibidor de bromodominio de benzodiacepina

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JP5937247B2 (ja) 2016-06-22
JP2015147777A (ja) 2015-08-20
JP2013532130A (ja) 2013-08-15

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