JP5709522B2 - 新規イメージング法 - Google Patents

新規イメージング法 Download PDF

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Publication number
JP5709522B2
JP5709522B2 JP2010534461A JP2010534461A JP5709522B2 JP 5709522 B2 JP5709522 B2 JP 5709522B2 JP 2010534461 A JP2010534461 A JP 2010534461A JP 2010534461 A JP2010534461 A JP 2010534461A JP 5709522 B2 JP5709522 B2 JP 5709522B2
Authority
JP
Japan
Prior art keywords
formula
compound
contrast agent
group
liver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2010534461A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011506273A (ja
JP2011506273A5 (https=
Inventor
チェッティビ、サラ
ニュートン、ベン
ソルバッケン、マグネ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of JP2011506273A publication Critical patent/JP2011506273A/ja
Publication of JP2011506273A5 publication Critical patent/JP2011506273A5/ja
Application granted granted Critical
Publication of JP5709522B2 publication Critical patent/JP5709522B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/14Peptides, e.g. proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2010534461A 2007-11-19 2008-11-19 新規イメージング法 Expired - Fee Related JP5709522B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98884007P 2007-11-19 2007-11-19
US60/988,840 2007-11-19
GBGB0722650.9A GB0722650D0 (en) 2007-11-19 2007-11-19 Novel imaging method
GB0722650.9 2007-11-19
PCT/EP2008/065824 WO2009071444A2 (en) 2007-11-19 2008-11-19 Novel imaging method

Publications (3)

Publication Number Publication Date
JP2011506273A JP2011506273A (ja) 2011-03-03
JP2011506273A5 JP2011506273A5 (https=) 2014-01-09
JP5709522B2 true JP5709522B2 (ja) 2015-04-30

Family

ID=38896533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010534461A Expired - Fee Related JP5709522B2 (ja) 2007-11-19 2008-11-19 新規イメージング法

Country Status (8)

Country Link
US (1) US8834843B2 (https=)
EP (1) EP2219681A2 (https=)
JP (1) JP5709522B2 (https=)
CN (1) CN101951964B (https=)
BR (1) BRPI0820430A2 (https=)
GB (1) GB0722650D0 (https=)
RU (1) RU2505316C2 (https=)
WO (1) WO2009071444A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2571486C1 (ru) * 2014-11-05 2015-12-20 Общество с ограниченной ответственностью "ДИАМЕД" Способ визуализации воспалений
EP3967704A4 (en) * 2019-06-11 2022-08-31 FUJIFILM Corporation CYCLIC PEPTIDE, CELL SCAFFOLD MATERIAL, CELL SEPARATOR MATERIAL AND CULTURE MEDIUM

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0210886B8 (pt) * 2001-07-10 2021-05-25 Amersham Health As composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal
US20040223912A1 (en) * 2003-05-07 2004-11-11 Montalto Michael Christopher Compositions and methods for non-invasive imaging of soluble beta-amyloid
GB0317815D0 (en) 2003-07-30 2003-09-03 Amersham Health As Imaging agents
ATE399542T1 (de) * 2003-10-01 2008-07-15 Merck Patent Gmbh Alfavbeta3 und alfavbeta6 integrin antagonisten als antifibrotische mittel
DE602005025911D1 (de) * 2004-11-22 2011-02-24 Ge Healthcare As Kontrastmittel für eine extrazelluläre matrix
EP1833512A1 (en) 2005-01-06 2007-09-19 GE Healthcare AS Optical imaging
WO2006115416A2 (en) 2005-04-25 2006-11-02 Ge Healthcare As Liposomes
CA2663749A1 (en) * 2005-09-21 2007-03-29 Dask Technologies, Llc Methods and compositions for organ and tissue functionality
GB0524987D0 (en) * 2005-12-08 2006-01-18 Ge Healthcare Ltd Novel imaging agents for fibrosis
WO2007148074A1 (en) 2006-06-21 2007-12-27 Hammersmith Imanet Limited Chemical methods and apparatus

Also Published As

Publication number Publication date
GB0722650D0 (en) 2007-12-27
CN101951964B (zh) 2013-05-29
CN101951964A (zh) 2011-01-19
JP2011506273A (ja) 2011-03-03
WO2009071444A9 (en) 2009-10-01
WO2009071444A2 (en) 2009-06-11
US20100316565A1 (en) 2010-12-16
EP2219681A2 (en) 2010-08-25
US8834843B2 (en) 2014-09-16
WO2009071444A3 (en) 2009-12-23
BRPI0820430A2 (pt) 2015-05-26
RU2010119187A (ru) 2011-12-27
RU2505316C2 (ru) 2014-01-27

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