CN101951964B - 成像方法 - Google Patents

成像方法 Download PDF

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Publication number
CN101951964B
CN101951964B CN200880117542.XA CN200880117542A CN101951964B CN 101951964 B CN101951964 B CN 101951964B CN 200880117542 A CN200880117542 A CN 200880117542A CN 101951964 B CN101951964 B CN 101951964B
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CN
China
Prior art keywords
chemical compound
formula
purposes
group
liver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200880117542.XA
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English (en)
Chinese (zh)
Other versions
CN101951964A (zh
Inventor
S·彻蒂比
B·牛顿
M·索尔贝肯
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GE Healthcare Ltd
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GE Healthcare Ltd
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Publication of CN101951964A publication Critical patent/CN101951964A/zh
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Publication of CN101951964B publication Critical patent/CN101951964B/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/14—Peptides, e.g. proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CN200880117542.XA 2007-11-19 2008-11-19 成像方法 Expired - Fee Related CN101951964B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US98884007P 2007-11-19 2007-11-19
GB0722650.9 2007-11-19
GBGB0722650.9A GB0722650D0 (en) 2007-11-19 2007-11-19 Novel imaging method
US60/988,840 2007-11-19
US60/988840 2007-11-19
PCT/EP2008/065824 WO2009071444A2 (en) 2007-11-19 2008-11-19 Novel imaging method

Publications (2)

Publication Number Publication Date
CN101951964A CN101951964A (zh) 2011-01-19
CN101951964B true CN101951964B (zh) 2013-05-29

Family

ID=38896533

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880117542.XA Expired - Fee Related CN101951964B (zh) 2007-11-19 2008-11-19 成像方法

Country Status (8)

Country Link
US (1) US8834843B2 (https=)
EP (1) EP2219681A2 (https=)
JP (1) JP5709522B2 (https=)
CN (1) CN101951964B (https=)
BR (1) BRPI0820430A2 (https=)
GB (1) GB0722650D0 (https=)
RU (1) RU2505316C2 (https=)
WO (1) WO2009071444A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2571486C1 (ru) * 2014-11-05 2015-12-20 Общество с ограниченной ответственностью "ДИАМЕД" Способ визуализации воспалений
WO2020250854A1 (ja) * 2019-06-11 2020-12-17 富士フイルム株式会社 環状ペプチド、細胞足場材、細胞分離材、及び培地

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006054904A2 (en) * 2004-11-22 2006-05-26 Ge Healthcare As Contrast agents to target extracellular matrix
WO2007066115A2 (en) * 2005-12-08 2007-06-14 Ge Healthcare Limited Novel imaging agents for fibrosis

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006491A2 (en) 2001-07-10 2003-01-23 Amersham Health As Peptide-based compounds for targeting intergin receptors
US20040223912A1 (en) * 2003-05-07 2004-11-11 Montalto Michael Christopher Compositions and methods for non-invasive imaging of soluble beta-amyloid
GB0317815D0 (en) * 2003-07-30 2003-09-03 Amersham Health As Imaging agents
EP1667668B1 (en) * 2003-10-01 2008-07-02 MERCK PATENT GmbH Alfavbeta3 and alfavbeta6 integrin antagonists as antifibrotic agents
CN101272808B (zh) 2005-01-06 2012-03-21 通用电气医疗集团股份有限公司 光学成像
EP1877100A2 (en) 2005-04-25 2008-01-16 GE Healthcare AS Liposomes
WO2007035843A2 (en) * 2005-09-21 2007-03-29 Dask Technologies, Llc Methods and compositions for organ and tissue functionality
WO2007148074A1 (en) 2006-06-21 2007-12-27 Hammersmith Imanet Limited Chemical methods and apparatus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006054904A2 (en) * 2004-11-22 2006-05-26 Ge Healthcare As Contrast agents to target extracellular matrix
WO2007066115A2 (en) * 2005-12-08 2007-06-14 Ge Healthcare Limited Novel imaging agents for fibrosis

Also Published As

Publication number Publication date
WO2009071444A9 (en) 2009-10-01
JP5709522B2 (ja) 2015-04-30
EP2219681A2 (en) 2010-08-25
JP2011506273A (ja) 2011-03-03
CN101951964A (zh) 2011-01-19
US20100316565A1 (en) 2010-12-16
RU2010119187A (ru) 2011-12-27
US8834843B2 (en) 2014-09-16
WO2009071444A3 (en) 2009-12-23
BRPI0820430A2 (pt) 2015-05-26
WO2009071444A2 (en) 2009-06-11
RU2505316C2 (ru) 2014-01-27
GB0722650D0 (en) 2007-12-27

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Granted publication date: 20130529

Termination date: 20161119

CF01 Termination of patent right due to non-payment of annual fee