CN101951964B - 成像方法 - Google Patents
成像方法 Download PDFInfo
- Publication number
- CN101951964B CN101951964B CN200880117542.XA CN200880117542A CN101951964B CN 101951964 B CN101951964 B CN 101951964B CN 200880117542 A CN200880117542 A CN 200880117542A CN 101951964 B CN101951964 B CN 101951964B
- Authority
- CN
- China
- Prior art keywords
- chemical compound
- formula
- purposes
- group
- liver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 C*(CC*(CC(*)C*(CC*(N)O)N)N1CC1)NC Chemical compound C*(CC*(CC(*)C*(CC*(N)O)N)N1CC1)NC 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98884007P | 2007-11-19 | 2007-11-19 | |
| US60/988,840 | 2007-11-19 | ||
| GBGB0722650.9A GB0722650D0 (en) | 2007-11-19 | 2007-11-19 | Novel imaging method |
| GB0722650.9 | 2007-11-19 | ||
| US60/988840 | 2007-11-19 | ||
| PCT/EP2008/065824 WO2009071444A2 (en) | 2007-11-19 | 2008-11-19 | Novel imaging method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101951964A CN101951964A (zh) | 2011-01-19 |
| CN101951964B true CN101951964B (zh) | 2013-05-29 |
Family
ID=38896533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200880117542.XA Expired - Fee Related CN101951964B (zh) | 2007-11-19 | 2008-11-19 | 成像方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8834843B2 (https=) |
| EP (1) | EP2219681A2 (https=) |
| JP (1) | JP5709522B2 (https=) |
| CN (1) | CN101951964B (https=) |
| BR (1) | BRPI0820430A2 (https=) |
| GB (1) | GB0722650D0 (https=) |
| RU (1) | RU2505316C2 (https=) |
| WO (1) | WO2009071444A2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2571486C1 (ru) * | 2014-11-05 | 2015-12-20 | Общество с ограниченной ответственностью "ДИАМЕД" | Способ визуализации воспалений |
| EP3967704A4 (en) * | 2019-06-11 | 2022-08-31 | FUJIFILM Corporation | CYCLIC PEPTIDE, CELL SCAFFOLD MATERIAL, CELL SEPARATOR MATERIAL AND CULTURE MEDIUM |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006054904A2 (en) * | 2004-11-22 | 2006-05-26 | Ge Healthcare As | Contrast agents to target extracellular matrix |
| WO2007066115A2 (en) * | 2005-12-08 | 2007-06-14 | Ge Healthcare Limited | Novel imaging agents for fibrosis |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0210886B8 (pt) * | 2001-07-10 | 2021-05-25 | Amersham Health As | composto, composição farmacêutica, uso de um composto, e, métodos de geração de imagens, de monitoração do efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condição associada com câncer e de tratamento de câncer ou de uma doença relacionada em um corpo humano ou animal |
| US20040223912A1 (en) * | 2003-05-07 | 2004-11-11 | Montalto Michael Christopher | Compositions and methods for non-invasive imaging of soluble beta-amyloid |
| GB0317815D0 (en) | 2003-07-30 | 2003-09-03 | Amersham Health As | Imaging agents |
| ATE399542T1 (de) * | 2003-10-01 | 2008-07-15 | Merck Patent Gmbh | Alfavbeta3 und alfavbeta6 integrin antagonisten als antifibrotische mittel |
| EP1833512A1 (en) | 2005-01-06 | 2007-09-19 | GE Healthcare AS | Optical imaging |
| WO2006115416A2 (en) | 2005-04-25 | 2006-11-02 | Ge Healthcare As | Liposomes |
| CA2663749A1 (en) * | 2005-09-21 | 2007-03-29 | Dask Technologies, Llc | Methods and compositions for organ and tissue functionality |
| WO2007148074A1 (en) | 2006-06-21 | 2007-12-27 | Hammersmith Imanet Limited | Chemical methods and apparatus |
-
2007
- 2007-11-19 GB GBGB0722650.9A patent/GB0722650D0/en not_active Ceased
-
2008
- 2008-11-19 WO PCT/EP2008/065824 patent/WO2009071444A2/en not_active Ceased
- 2008-11-19 RU RU2010119187/15A patent/RU2505316C2/ru not_active IP Right Cessation
- 2008-11-19 BR BRPI0820430-6A patent/BRPI0820430A2/pt not_active IP Right Cessation
- 2008-11-19 JP JP2010534461A patent/JP5709522B2/ja not_active Expired - Fee Related
- 2008-11-19 EP EP08856281A patent/EP2219681A2/en not_active Withdrawn
- 2008-11-19 CN CN200880117542.XA patent/CN101951964B/zh not_active Expired - Fee Related
- 2008-11-19 US US12/742,984 patent/US8834843B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006054904A2 (en) * | 2004-11-22 | 2006-05-26 | Ge Healthcare As | Contrast agents to target extracellular matrix |
| WO2007066115A2 (en) * | 2005-12-08 | 2007-06-14 | Ge Healthcare Limited | Novel imaging agents for fibrosis |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0722650D0 (en) | 2007-12-27 |
| CN101951964A (zh) | 2011-01-19 |
| JP2011506273A (ja) | 2011-03-03 |
| WO2009071444A9 (en) | 2009-10-01 |
| WO2009071444A2 (en) | 2009-06-11 |
| US20100316565A1 (en) | 2010-12-16 |
| EP2219681A2 (en) | 2010-08-25 |
| US8834843B2 (en) | 2014-09-16 |
| WO2009071444A3 (en) | 2009-12-23 |
| BRPI0820430A2 (pt) | 2015-05-26 |
| RU2010119187A (ru) | 2011-12-27 |
| RU2505316C2 (ru) | 2014-01-27 |
| JP5709522B2 (ja) | 2015-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101454026B (zh) | 成像剂 | |
| EP0772628B1 (en) | Peptide derived radionuclide chelators | |
| ES2844586T3 (es) | Inhibidores del antígeno prostático específico de membrana (PSMA) etiquetados con 18F y su uso como agentes de obtención de imágenes para el cáncer de próstata | |
| US9550001B2 (en) | Compositions, methods of synthesis and use of carbohydrate targeted agents | |
| EP0746340B1 (en) | Peptide-chelator conjugates | |
| EP0733060B1 (en) | Metal chelators | |
| CN114773433B (zh) | 一种cd25靶向多肽、分子探针及应用 | |
| CN101325978A (zh) | 用于纤维化的新显像剂 | |
| US20210347890A1 (en) | Cd31shed as a molecular target for imaging of inflammation | |
| Yim et al. | Synthesis and preclinical characterization of [64Cu] NODAGA-MAL-exendin-4 with a Nε-maleoyl-l-lysyl-glycine linkage | |
| CN112043839A (zh) | 靶向转铁蛋白受体的放射性同位素标记多肽显像剂及其应用 | |
| Nock et al. | Novel bifunctional DATA chelator for quick access to site-directed PET 68 Ga-radiotracers: preclinical proof-of-principle with [Tyr 3] octreotide | |
| CN101951964B (zh) | 成像方法 | |
| US7122622B2 (en) | Peptide compounds having improved binding affinity to somatostatin receptors | |
| TWI671077B (zh) | 六聚乳糖NOTA衍生物、六聚乳糖正子肝受體造影劑的Ga-68放射標誌方法及六聚乳糖正子肝受體造影劑 | |
| JP7091241B2 (ja) | 固形ガンのための新規なキニンベースのセラノスティックプローブとその使用 | |
| JP2008509921A (ja) | 内皮特異的な生体内伝達のターゲティング剤としての熱ショックタンパク質 | |
| EP4640240A1 (en) | Peptide-based radiopharmaceuticals for non-invasive imaging of the functional liver reserve | |
| CN119613501A (zh) | 靶向肿瘤整合素α5β1的PET示踪剂及其标记前体、制备方法和应用 | |
| CN115996761A (zh) | 用于诊断和/或监测纤维化的化合物 | |
| KR20120027023A (ko) | 섬유생성화의 pet 영상화 | |
| Hua | Research Progress on Asialoglycoprotein Receptor-Targeted Radiopharmaceuticals Designed for Hepatic Nuclear Medicine Imaging |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20130529 Termination date: 20161119 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |