JP5705113B2 - Il−10産生の刺激のためのアレルゲン由来のt細胞抗原 - Google Patents

Il−10産生の刺激のためのアレルゲン由来のt細胞抗原 Download PDF

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JP5705113B2
JP5705113B2 JP2011522551A JP2011522551A JP5705113B2 JP 5705113 B2 JP5705113 B2 JP 5705113B2 JP 2011522551 A JP2011522551 A JP 2011522551A JP 2011522551 A JP2011522551 A JP 2011522551A JP 5705113 B2 JP5705113 B2 JP 5705113B2
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sequence
polypeptide
peptide
protein
allergen
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Expired - Fee Related
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JP2011522551A
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Japanese (ja)
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JP2012500194A5 (enExample
JP2012500194A (ja
Inventor
ラルシェ、マーク
ハフナー、ロデリック、ピーター
レイドラー、ポール
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サーカッシア リミテッド
サーカッシア リミテッド
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Priority claimed from GB0814986A external-priority patent/GB0814986D0/en
Priority claimed from PCT/GB2008/002781 external-priority patent/WO2009022157A2/en
Priority claimed from GB0815218A external-priority patent/GB0815218D0/en
Priority claimed from GBGB0901927.4A external-priority patent/GB0901927D0/en
Priority claimed from EP09251252.4A external-priority patent/EP2153841B2/en
Priority claimed from GB0912578A external-priority patent/GB0912578D0/en
Application filed by サーカッシア リミテッド, サーカッシア リミテッド filed Critical サーカッシア リミテッド
Publication of JP2012500194A publication Critical patent/JP2012500194A/ja
Publication of JP2012500194A5 publication Critical patent/JP2012500194A5/ja
Publication of JP5705113B2 publication Critical patent/JP5705113B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
JP2011522551A 2008-08-15 2009-08-14 Il−10産生の刺激のためのアレルゲン由来のt細胞抗原 Expired - Fee Related JP5705113B2 (ja)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
GB0814986.6 2008-08-15
GB0814986A GB0814986D0 (en) 2008-08-15 2008-08-15 Peptide for il10 production
GBPCT/GB08/002779 2008-08-15
GBPCT/GB08/002778 2008-08-15
GBPCT/GB08/002780 2008-08-15
PCT/GB2008/002781 WO2009022157A2 (en) 2007-08-15 2008-08-15 Peptide with improved solubility
PCT/GB2008/002779 WO2009022155A2 (en) 2007-08-15 2008-08-15 Peptide with reduced dimer formation
GBPCT/GB08/002781 2008-08-15
PCT/GB2008/002780 WO2009022156A2 (en) 2007-08-15 2008-08-15 Peptides for desensibilization against allergens
PCT/GB2008/002778 WO2009022154A2 (en) 2007-08-15 2008-08-15 Peptide with multiple epitopes
GB0815218A GB0815218D0 (en) 2008-08-20 2008-08-20 Ragweed peptides for vaccine
GB0815218.3 2008-08-20
GB0901927.4 2009-02-05
GBGB0901927.4A GB0901927D0 (en) 2009-02-05 2009-02-05 Peptide for IL10 production
EP09251252.4A EP2153841B2 (en) 2008-08-15 2009-05-01 Vaccine comprising Amb a 1 peptides for use in the treatment of ragweed allergy
EP09251252.4 2009-05-01
GB0912578A GB0912578D0 (en) 2009-07-20 2009-07-20 Peptide for IL-10 production
GB0912578.2 2009-07-20
PCT/GB2009/001995 WO2010018384A1 (en) 2008-08-15 2009-08-14 T-cell antigen peptide from allergen for stimulation of il-10 production

Publications (3)

Publication Number Publication Date
JP2012500194A JP2012500194A (ja) 2012-01-05
JP2012500194A5 JP2012500194A5 (enExample) 2012-10-04
JP5705113B2 true JP5705113B2 (ja) 2015-04-22

Family

ID=41112622

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011522551A Expired - Fee Related JP5705113B2 (ja) 2008-08-15 2009-08-14 Il−10産生の刺激のためのアレルゲン由来のt細胞抗原

Country Status (4)

Country Link
US (2) US8821887B2 (enExample)
EP (1) EP2331124A1 (enExample)
JP (1) JP5705113B2 (enExample)
WO (1) WO2010018384A1 (enExample)

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JP2014521687A (ja) 2011-07-29 2014-08-28 セレクタ バイオサイエンシーズ インコーポレーテッド 体液性および細胞傷害性tリンパ球(ctl)免疫応答を生成する合成ナノキャリア
GB201209862D0 (en) 2012-06-01 2012-07-18 Circassia Ltd Cladosporium peptides
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CN105307641A (zh) 2013-05-03 2016-02-03 西莱克塔生物科技公司 用于降低不期望体液免疫应答的给药组合
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CN105848677B (zh) * 2013-12-23 2020-01-31 爱尔开-阿贝优公司 在治疗尘螨过敏症中的肽组合及其用途
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US12553041B2 (en) 2019-06-04 2026-02-17 Cartesian Therapeutics Inc. Formulations and doses of pegylated uricase
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Also Published As

Publication number Publication date
US20140328868A1 (en) 2014-11-06
US20110206709A1 (en) 2011-08-25
EP2331124A1 (en) 2011-06-15
WO2010018384A1 (en) 2010-02-18
US8821887B2 (en) 2014-09-02
JP2012500194A (ja) 2012-01-05

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