JP5703432B2 - プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用 - Google Patents

プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用 Download PDF

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JP5703432B2
JP5703432B2 JP2010500272A JP2010500272A JP5703432B2 JP 5703432 B2 JP5703432 B2 JP 5703432B2 JP 2010500272 A JP2010500272 A JP 2010500272A JP 2010500272 A JP2010500272 A JP 2010500272A JP 5703432 B2 JP5703432 B2 JP 5703432B2
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methyl
phenyl
purin
amine
chloro
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JP2010522718A5 (enExample
JP2010522718A (ja
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エリクセン、ビルジット、エル．
セレンセン、ウルリック、スバーン
ホーガード、シャルロット
ペータース、ダン
ヨハンセン、ティナ、ホルム
クリストファーセン、パレ
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ノイロサーチ アクティーゼルスカブ
ノイロサーチ アクティーゼルスカブ
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Priority claimed from PCT/EP2008/053648 external-priority patent/WO2008116909A1/en
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    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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JP2010500272A 2007-03-28 2008-03-27 プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用 Active JP5703432B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90850307P 2007-03-28 2007-03-28
DKPA200700482 2007-03-28
DKPA200700482 2007-03-28
US60/908,503 2007-03-28
PCT/EP2008/053648 WO2008116909A1 (en) 2007-03-28 2008-03-27 Purinyl derivatives and their use as potassium channel modulators

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JP2010522718A JP2010522718A (ja) 2010-07-08
JP2010522718A5 JP2010522718A5 (enExample) 2011-05-12
JP5703432B2 true JP5703432B2 (ja) 2015-04-22

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JP2010500275A Pending JP2010522721A (ja) 2007-03-28 2008-03-27 プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用
JP2010500273A Pending JP2010522719A (ja) 2007-03-28 2008-03-27 プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用
JP2010500274A Pending JP2010522720A (ja) 2007-03-28 2008-03-27 プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用
JP2010500272A Active JP5703432B2 (ja) 2007-03-28 2008-03-27 プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用
JP2010500276A Pending JP2010522722A (ja) 2007-03-28 2008-03-27 プリニル誘導体及びカリウムチャネルモジュレーターとしてのそれらの使用

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CN101646669B (zh) 2013-09-04
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BRPI0808746A2 (pt) 2014-08-19
EP2402341A3 (en) 2014-11-12
KR101564233B1 (ko) 2015-10-29
JP2010522720A (ja) 2010-07-08
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EP2402341B1 (en) 2017-10-25
CN101646669A (zh) 2010-02-10
BRPI0808746B1 (pt) 2020-09-24
BRPI0808746B8 (pt) 2021-05-25
JP2010522722A (ja) 2010-07-08
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US20100105705A1 (en) 2010-04-29
RU2009132881A (ru) 2011-05-10
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ZA200905796B (en) 2010-10-27
EP2402341A2 (en) 2012-01-04
US20120004246A1 (en) 2012-01-05
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JP2010522718A (ja) 2010-07-08

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