RU2468026C2 - Производные пуринила и их применение в качестве модуляторов калиевых каналов - Google Patents

Производные пуринила и их применение в качестве модуляторов калиевых каналов Download PDF

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Publication number
RU2468026C2
RU2468026C2 RU2009132881/04A RU2009132881A RU2468026C2 RU 2468026 C2 RU2468026 C2 RU 2468026C2 RU 2009132881/04 A RU2009132881/04 A RU 2009132881/04A RU 2009132881 A RU2009132881 A RU 2009132881A RU 2468026 C2 RU2468026 C2 RU 2468026C2
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Russia
Prior art keywords
methyl
purin
phenyl
pyrazol
chloro
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RU2009132881/04A
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English (en)
Russian (ru)
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RU2009132881A (ru
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Биргитте Л. ЭРИКСЕН
Ульрик Сване СЁРЕНСЕН
Шарлотте ХУГОРД
Дан ПЕТЕРС
Тина Хольм ЙОХАНСЕН
Пале КРИСТОФЕРСЕН
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НьюроСёрч А/С
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Priority claimed from PCT/EP2008/053648 external-priority patent/WO2008116909A1/en
Publication of RU2009132881A publication Critical patent/RU2009132881A/ru
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Publication of RU2468026C2 publication Critical patent/RU2468026C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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RU2009132881/04A 2007-03-28 2008-03-27 Производные пуринила и их применение в качестве модуляторов калиевых каналов RU2468026C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90850307P 2007-03-28 2007-03-28
DKPA200700482 2007-03-28
DKPA200700482 2007-03-28
US60/908,503 2007-03-28
PCT/EP2008/053648 WO2008116909A1 (en) 2007-03-28 2008-03-27 Purinyl derivatives and their use as potassium channel modulators

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RU2009132881A RU2009132881A (ru) 2011-05-10
RU2468026C2 true RU2468026C2 (ru) 2012-11-27

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US (2) US20120004246A1 (enExample)
EP (1) EP2402341B1 (enExample)
JP (5) JP2010522721A (enExample)
KR (1) KR101564233B1 (enExample)
CN (1) CN101646669B (enExample)
BR (1) BRPI0808746B8 (enExample)
NZ (1) NZ579248A (enExample)
RU (1) RU2468026C2 (enExample)
UA (1) UA98482C2 (enExample)
ZA (1) ZA200905796B (enExample)

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EP2114916A2 (en) * 2007-02-02 2009-11-11 NeuroSearch A/S Pyridinyl-pyrazole derivatives and their use as potassium channel modulators
EP2142547A1 (en) * 2007-03-28 2010-01-13 NeuroSearch A/S Purinyl derivatives and their use as potassium channel modulators
NZ579248A (en) * 2007-03-28 2011-08-26 Neurosearch As Purinyl derivatives and their use as potassium channel modulators
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