JP5697448B2 - 膀胱癌の検出のための新規なマーカー - Google Patents

膀胱癌の検出のための新規なマーカー Download PDF

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JP5697448B2
JP5697448B2 JP2010524399A JP2010524399A JP5697448B2 JP 5697448 B2 JP5697448 B2 JP 5697448B2 JP 2010524399 A JP2010524399 A JP 2010524399A JP 2010524399 A JP2010524399 A JP 2010524399A JP 5697448 B2 JP5697448 B2 JP 5697448B2
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gene
bladder cancer
nid2
sample
twist1
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JP2010538624A (ja
JP2010538624A5 (enExample
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イザベル レナール,
イザベル レナール,
クリエキンジェ, ウィム ファン
クリエキンジェ, ウィム ファン
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エムディーエックスヘルス エスエー
エムディーエックスヘルス エスエー
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010524399A 2007-09-17 2008-09-11 膀胱癌の検出のための新規なマーカー Active JP5697448B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US96012907P 2007-09-17 2007-09-17
US60/960,129 2007-09-17
US7197108P 2008-05-28 2008-05-28
US61/071,971 2008-05-28
GBPCT/GB2008/002093 2008-06-19
PCT/GB2008/002093 WO2008155549A2 (en) 2007-06-19 2008-06-19 Improved urine sample collecting and processing
PCT/EP2008/007465 WO2009036922A2 (en) 2007-09-17 2008-09-11 Novel markers for bladder cancer detection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014208231A Division JP2015051006A (ja) 2007-09-17 2014-10-09 膀胱癌の検出のための新規なマーカー

Publications (3)

Publication Number Publication Date
JP2010538624A JP2010538624A (ja) 2010-12-16
JP2010538624A5 JP2010538624A5 (enExample) 2011-11-04
JP5697448B2 true JP5697448B2 (ja) 2015-04-08

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JP2010524399A Active JP5697448B2 (ja) 2007-09-17 2008-09-11 膀胱癌の検出のための新規なマーカー
JP2014208231A Pending JP2015051006A (ja) 2007-09-17 2014-10-09 膀胱癌の検出のための新規なマーカー

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JP2014208231A Pending JP2015051006A (ja) 2007-09-17 2014-10-09 膀胱癌の検出のための新規なマーカー

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US (2) US9322065B2 (enExample)
EP (2) EP3147375A1 (enExample)
JP (2) JP5697448B2 (enExample)
CA (1) CA2699606C (enExample)
DK (1) DK2198042T3 (enExample)
ES (1) ES2605237T3 (enExample)
PL (1) PL2198042T3 (enExample)
WO (1) WO2009036922A2 (enExample)

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* Cited by examiner, † Cited by third party
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JP2015051006A (ja) * 2007-09-17 2015-03-19 エムディーエックスヘルス エスエー 膀胱癌の検出のための新規なマーカー

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CA2755358A1 (en) 2009-03-13 2010-09-16 Mdxhealth Sa Novel markers for bladder cancer detection
JPWO2010113529A1 (ja) * 2009-04-03 2012-10-04 株式会社エイアンドティー 大腸腫瘍の検出方法
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ES2669439T3 (es) * 2009-06-26 2018-05-25 Epigenomics Ag Métodos y ácidos nucleicos para el análisis del carcinoma de vejiga
WO2011101728A2 (en) 2010-02-19 2011-08-25 Nucleix Identification of source of dna samples
US9752187B2 (en) 2009-12-11 2017-09-05 Nucleix Categorization of DNA samples
WO2011104731A1 (en) * 2010-02-26 2011-09-01 Decode Genetics Ehf Genetic variants as markers for use in urinary bladder cancer risk assessment, diagnosis, prognosis and treatment
US9328379B2 (en) * 2010-03-12 2016-05-03 The Johns Hopkins University Hypermethylation biomarkers for detection of head and neck squamous cell cancer
US20130041047A1 (en) * 2011-06-01 2013-02-14 Aros Applied Biotechnology As Urinary Methylation Markers for Bladder Cancer
US10323285B2 (en) 2013-09-09 2019-06-18 Nantomics, Llc Proteomics analysis and discovery through DNA and RNA sequencing, systems and methods
US10689652B2 (en) 2013-10-02 2020-06-23 The Regents Of The University Of California Methods for immortalization of epithelial cells
US9476100B1 (en) * 2015-07-06 2016-10-25 Nucleix Ltd. Methods for diagnosing bladder cancer
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WO2017062517A1 (en) * 2015-10-06 2017-04-13 The Regents Of The University Of California Non-coding rnas linked to immortality and associated methods and compositions
WO2017062989A1 (en) * 2015-10-08 2017-04-13 Urology Diagnostics, Inc. Diagnostic assay for urine monitoring of bladder cancer
RU2612139C1 (ru) * 2015-12-29 2017-03-02 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Набор синтетических олигонуклеотидов для определения уровней экспрессии гена pdlim4
CA3019381A1 (en) * 2016-04-01 2017-10-05 Nanomed Diagnostics B.V. Detection of cancer in urine
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WO2018047883A1 (ja) * 2016-09-06 2018-03-15 株式会社ユカシカド スポット尿を用いたヘルスケアシステム
CN109844139A (zh) * 2016-09-29 2019-06-04 哈鲁曼有限公司 散发性大肠癌发病可能性的判定方法
CN107014658B (zh) * 2017-05-27 2023-08-25 四川省肿瘤医院 提取游离细胞的方法及试剂盒
CN110997933B (zh) * 2017-08-02 2024-01-09 萨斯特德特股份有限两合公司 用于稳定无细胞核酸和细胞的方法和组合物
EP3821038A1 (en) * 2018-07-11 2021-05-19 Stichting VUmc Urine dna methylation markers for bladder cancer
IL265451B (en) 2019-03-18 2020-01-30 Frumkin Dan Methods and systems for the detection of methylation changes in DNA samples
KR102186534B1 (ko) * 2019-04-11 2020-12-03 차의과학대학교 산학협력단 수지상세포의 성숙도 측정 방법 및 조성물, 그리고 이의 용도
CN110283914A (zh) * 2019-07-29 2019-09-27 上海透景生命科技股份有限公司 一种膀胱癌的新型基因诊断试剂盒及其应用
CN113943799B (zh) * 2020-07-16 2023-12-15 广州达健生物科技有限公司 用于检测膀胱癌的组合物及其试剂盒和应用
CN113957160B (zh) * 2020-07-20 2024-03-29 深圳华大生命科学研究院 检测膀胱癌的标志物及检测该标志物的引物对及其应用
CN115094139B (zh) * 2022-06-22 2023-04-28 武汉艾米森生命科技有限公司 检测甲基化水平的试剂在制备膀胱癌诊断产品中的应用以及膀胱癌诊断试剂盒
CN116004831B (zh) * 2023-01-05 2024-10-01 武汉艾米森生命科技有限公司 一种用于膀胱癌的诊断或辅助诊断的试剂及检测试剂盒
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CN117265114A (zh) * 2023-10-13 2023-12-22 青岛瑞思德医学检验实验室有限公司 一种膀胱癌检测试剂盒及检测方法
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015051006A (ja) * 2007-09-17 2015-03-19 エムディーエックスヘルス エスエー 膀胱癌の検出のための新規なマーカー

Also Published As

Publication number Publication date
CA2699606A1 (en) 2009-03-26
ES2605237T3 (es) 2017-03-13
US20100280134A1 (en) 2010-11-04
EP3147375A1 (en) 2017-03-29
WO2009036922A3 (en) 2009-05-28
WO2009036922A2 (en) 2009-03-26
DK2198042T3 (en) 2017-01-23
JP2015051006A (ja) 2015-03-19
JP2010538624A (ja) 2010-12-16
EP2198042B1 (en) 2016-11-02
EP2198042A2 (en) 2010-06-23
US20160208341A1 (en) 2016-07-21
CA2699606C (en) 2023-04-11
US10113202B2 (en) 2018-10-30
US9322065B2 (en) 2016-04-26
PL2198042T3 (pl) 2017-05-31

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