JP5687425B2 - 肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤 - Google Patents

肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤 Download PDF

Info

Publication number
JP5687425B2
JP5687425B2 JP2009514226A JP2009514226A JP5687425B2 JP 5687425 B2 JP5687425 B2 JP 5687425B2 JP 2009514226 A JP2009514226 A JP 2009514226A JP 2009514226 A JP2009514226 A JP 2009514226A JP 5687425 B2 JP5687425 B2 JP 5687425B2
Authority
JP
Japan
Prior art keywords
antibody
subunit
drug
treatment
insulin receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2009514226A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009539827A (ja
JP2009539827A5 (https=
Inventor
オレグ イリッチ エプシュテイン
オレグ イリッチ エプシュテイン
スベトラーナ アレクサンドロブナ セルゲーエバ
スベトラーナ アレクサンドロブナ セルゲーエバ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2006119655/15A external-priority patent/RU2438707C2/ru
Priority claimed from RU2006119658/15A external-priority patent/RU2437678C2/ru
Application filed by Individual filed Critical Individual
Publication of JP2009539827A publication Critical patent/JP2009539827A/ja
Publication of JP2009539827A5 publication Critical patent/JP2009539827A5/ja
Application granted granted Critical
Publication of JP5687425B2 publication Critical patent/JP5687425B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Emergency Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2009514226A 2006-06-06 2007-05-31 肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤 Expired - Fee Related JP5687425B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
RU2006119655 2006-06-06
RU2006119655/15A RU2438707C2 (ru) 2006-06-06 2006-06-06 Лекарственное средство для перорального лечения сахарного диабета и других заболеваний, сопровождающихся нарушением толерантности к глюкозе, и способ получения твердой лекарственной формы для пероральной терапии сахарного диабета и других заболеваний, сопровождающихся нарушением толерантности к глюкозе
RU2006119658 2006-06-06
RU2006119658/15A RU2437678C2 (ru) 2006-06-06 2006-06-06 Лекарственное средство для перорального лечения ожирения и способ получения твердой лекарственной формы для пероральной терапии ожирения
PCT/RU2007/000288 WO2007149010A1 (en) 2006-06-06 2007-05-31 Medicinal agent for treating fatness, diabetes, and diseases associated with impaired glucose tolerance

Publications (3)

Publication Number Publication Date
JP2009539827A JP2009539827A (ja) 2009-11-19
JP2009539827A5 JP2009539827A5 (https=) 2013-03-21
JP5687425B2 true JP5687425B2 (ja) 2015-03-18

Family

ID=38833657

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009514226A Expired - Fee Related JP5687425B2 (ja) 2006-06-06 2007-05-31 肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤

Country Status (11)

Country Link
US (2) US9308259B2 (https=)
EP (2) EP2036574A4 (https=)
JP (1) JP5687425B2 (https=)
KR (1) KR20090024241A (https=)
AU (1) AU2007261782A1 (https=)
BR (1) BRPI0712540A2 (https=)
CA (1) CA2654408C (https=)
EA (1) EA200802440A1 (https=)
IL (2) IL195755A (https=)
MX (1) MX2008015621A (https=)
WO (1) WO2007149010A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2181297C2 (ru) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
RU2309732C1 (ru) 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
EP2036574A4 (en) 2006-06-06 2009-07-01 Oleg Iliich Epshtein MEDICAL AGENT FOR THE TREATMENT OF FAT, DIABETES AND DISEASES IN CONNECTION WITH IMPROVED GLUCOSE TOLERANCE
JP5616428B2 (ja) 2009-04-07 2014-10-29 ロシュ グリクアート アクチェンゲゼルシャフト 三価の二重特異性抗体
US9676845B2 (en) 2009-06-16 2017-06-13 Hoffmann-La Roche, Inc. Bispecific antigen binding proteins
CN102597775A (zh) 2009-09-25 2012-07-18 佐马技术有限公司 筛选方法
US8926976B2 (en) 2009-09-25 2015-01-06 Xoma Technology Ltd. Modulators
SG10201505564VA (en) * 2010-07-15 2015-09-29 Oleg Iliich Epshtein Combination pharmaceutical composition and methods of treating genitourinary system disorders
ITTO20110641A1 (it) * 2010-07-15 2012-01-16 Oleg Iliich Epshtein Composizioni farmaceutiche e metodi di trattamento
FR2962656A1 (fr) * 2010-07-15 2012-01-20 Oleg Iliich Epshtein Procede pour augmenter l'effet d'une forme activee-potentialisee d'un anticorps
EA029436B1 (ru) 2010-07-15 2018-03-30 Олег Ильич ЭПШТЕЙН Комбинированная фармацевтическая композиция для лечения рассеянного склероза и инфекционных заболеваний, сопровождающихся нейротоксическими нарушениями, и способы лечения указанных заболеваний
RU2610438C2 (ru) * 2011-06-02 2017-02-10 Общество С Ограниченной Ответственностью "Научно-Производственная Фирма "Материа Медика Холдинг" Способ лечения патологического синдрома и лекарственное средство центрального и периферического действия для лечения патологического синдрома
NZ606977A (en) * 2010-07-21 2015-08-28 Oleg Iliich Epshtein Combination pharmaceutical composition and methods of treating diseases or conditions associated with respiratory disease or condition
EP2596019A2 (en) 2010-07-21 2013-05-29 Oleg Iliich Epshtein A method of treating attention deficit hyperactivity disorder
EP3693018A1 (en) * 2010-07-21 2020-08-12 Oleg Iliich Epshtein A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders
KR20140012021A (ko) * 2010-08-06 2014-01-29 올레그 일리치 엡쉬테인 감염성 질환의 치료 및 예방을 위한 제약학적 복합 조성물 및 방법들
WO2012116926A1 (en) 2011-02-28 2012-09-07 F. Hoffmann-La Roche Ag Antigen binding proteins
JP5768147B2 (ja) 2011-02-28 2015-08-26 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 一価抗原結合タンパク質
ES2688591T3 (es) * 2011-03-28 2018-11-05 Ablynx N.V. Método para producir formulaciones sólidas que comprenden dominios variables individuales de inmunoglobulina
RU2013111962A (ru) 2013-03-18 2014-09-27 Олег Ильич Эпштейн Способ определения выраженности модифицирующей активности, ассоциированной с носителем
RU2013111961A (ru) 2013-03-18 2014-09-27 Олег Ильич Эпштейн Способ определения выраженности модифицирующей активности, ассоциированной с носителем
KR20160044060A (ko) 2013-10-11 2016-04-22 에프. 호프만-라 로슈 아게 다중특이적 도메인 교환된 통상의 가변 경쇄 항체
RU2603623C2 (ru) * 2014-06-06 2016-11-27 Олег Ильич Эпштейн Ветеринарная композиция и способ улучшения жизнеспособности животных, стимуляции прироста живой массы млекопитающих и птиц, повышения эффективности иммунизации, профилактики и/или лечения инфекционных заболеваний (варианты)
CN107001482B (zh) 2014-12-03 2021-06-15 豪夫迈·罗氏有限公司 多特异性抗体
WO2016172479A1 (en) * 2015-04-22 2016-10-27 Cedars-Sinai Medical Center Enterically delivered bitter oligopeptides for the treatment for type 2 diabetes
AU2016304588A1 (en) 2015-08-06 2018-02-15 Xoma (Us) Llc Antibody fragments against the insulin receptor and uses thereof to treat hypoglycemia
WO2025171378A1 (en) 2024-02-09 2025-08-14 Rezolute, Inc. Insulin receptor modulation for tumor associated hyperinsulinism

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4839341A (en) * 1984-05-29 1989-06-13 Eli Lilly And Company Stabilized insulin formulations
JPS61176534A (ja) * 1985-01-30 1986-08-08 Takashi Muramatsu 避妊用剤
US4761371A (en) * 1985-02-12 1988-08-02 Genentech, Inc. Insulin receptor
US6803452B2 (en) 1991-02-26 2004-10-12 New York University RPTP-β antibodies
US5698195A (en) * 1991-03-18 1997-12-16 New York University Medical Center Methods of treating rheumatoid arthritis using chimeric anti-TNF antibodies
RU2007989C1 (ru) 1991-11-12 1994-02-28 Акционерное общество "Трейдис" Способ габович подбора гомеопатических препаратов и их разовой дозы
DK140992D0 (da) 1992-11-24 1992-11-24 Ole Buchardt Fremgangsmaade til frembringelse af antistoffer mod haptener og andre b-celle-antigener, antistoffer opnaaet ved fremgangsmaaden og anvendelse af disse antistoffer til fremstilling af vacciner, isaer til veterinaermedicinsk brug
US5879677A (en) 1992-12-09 1999-03-09 The Scripps Research Institute Method for inhibition of cerebral tissue factor mediated reperfusion damage
RU2033784C1 (ru) 1993-05-28 1995-04-30 Индивидуальное частное предприятие "Диалог" Устройство для репродуцирования гомеопатических и изопатических препаратов
IT1261849B (it) * 1993-09-02 1996-06-03 Avantgarde Spa Dispositivo medico per la somministrazione di principi attivi o farmaci a bassissimo dosaggio, in particolare di farmaci omeopatici.
EP0652014A1 (en) 1993-11-10 1995-05-10 National Institute Of Immunology Treatment of prostatic hypertrophy
WO1995023231A1 (en) 1994-02-28 1995-08-31 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Cell lines for the identification of substances affecting insulin receptor mediated signal transduction
US5861266A (en) 1994-02-28 1999-01-19 New York University Treatment of diabetes mellitus and insulin receptor signal transduction
IL110035A0 (en) 1994-06-16 1994-10-07 Tapuach Natural Technologies 1 Homeopathic formulations
RU2137483C1 (ru) 1995-08-02 1999-09-20 Божедомов Владимир Александрович Способ лечения урогенитальной хламидийной, уреаплазменной и микоплазменной инфекции
UA32457C2 (uk) 1996-02-12 2000-12-15 Олєг Ільіч Епштейн Лікарський засіб (варіанти) і спосіб медикаментозного впливу на організм
US5726027A (en) * 1996-03-08 1998-03-10 The Regents Of The University Of California Method for treatment of insulin resistance
GB9613470D0 (en) 1996-06-27 1996-08-28 Ciba Geigy Ag Small solid oral dosage form
RU2114646C1 (ru) 1996-09-30 1998-07-10 Олег Ильич Эпштейн Способ повышения защитных свойств организма при воздействии внешних физических факторов
RU2104032C1 (ru) 1997-03-11 1998-02-10 Общество с ограниченной ответственностью "Снежный барс" Способ усиления лечебного эффекта лекарственных средств
RU2122858C1 (ru) 1997-12-29 1998-12-10 Яковлева Людмила Борисовна Гомеопатическое лекарственное средство седативного действия "вернисон"
DE69910183T2 (de) * 1998-03-11 2004-06-03 Grelan Pharmaceutical Co., Ltd., Hamura Darmlösliche sprudelnde zusammensetzungen
RU2187334C2 (ru) 1998-05-22 2002-08-20 Эпштейн Олег Ильич Способ коррекции нарушенного иммунного гомеостаза и лекарственное средство
US6007824A (en) 1998-07-09 1999-12-28 Duckett; Melvin J. Natural composition and method for the treatment of sexual dysfunction
RU2144370C1 (ru) 1999-01-06 2000-01-20 Титиева Наталья Михайловна Гомеопатическое лекарственное средство для лечения гипертрофии предстательной железы
RU2161955C1 (ru) 1999-07-16 2001-01-20 Эпштейн Олег Ильич Способ изменения физико-химических или физико-химических и биологических свойств вещества
RU2181297C2 (ru) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
AU2002232394A1 (en) 2000-10-27 2002-05-27 Wayne State University Inhibition of alpha-2 hs glycoprotein (ahsg/fetuin) in obesity and insulin control of glucose homeostasis
RU2192882C1 (ru) 2001-04-18 2002-11-20 Эпштейн Олег Ильич Лекарственное средство и способ лечения патологического синдрома, обусловленного нарушением кроветворения
RU2199345C1 (ru) 2001-12-26 2003-02-27 Эпштейн Олег Ильич Лекарственное средство и способ регуляции углеводного и жирового обмена
AUPS019802A0 (en) * 2002-01-31 2002-02-21 Chemstop Pty Ltd Nutrient formulation
UA76641C2 (uk) * 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Гомеопатичний лікарський засіб та спосіб лікування захворювань передміхурової залози
AU2002325432A1 (en) 2002-08-02 2004-02-23 Alexandr Mikhailovich Dygay Medicinal agent and method for curing pathological syndrome associated to hemodiscrasia
UA76638C2 (en) * 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
UA76639C2 (uk) * 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Гомеопатичний лікарський засіб та спосіб лікування еректильних дисфункцій
RU2253478C1 (ru) * 2003-10-01 2005-06-10 Эпштейн Олег Ильич Средство для потенцирования лечебных эффектов - усиления действия лекарственного вещества
RU2309732C1 (ru) 2006-03-13 2007-11-10 Олег Ильич Эпштейн Спрессованная твердая оральная форма лекарственного препарата и способ получения твердой оральной формы лекарственного препарата
EP2036574A4 (en) 2006-06-06 2009-07-01 Oleg Iliich Epshtein MEDICAL AGENT FOR THE TREATMENT OF FAT, DIABETES AND DISEASES IN CONNECTION WITH IMPROVED GLUCOSE TOLERANCE
EP3693018A1 (en) * 2010-07-21 2020-08-12 Oleg Iliich Epshtein A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders

Also Published As

Publication number Publication date
EP2036574A1 (en) 2009-03-18
CA2654408A1 (en) 2007-12-27
IL195755A0 (en) 2011-08-01
AU2007261782A1 (en) 2007-12-27
BRPI0712540A2 (pt) 2012-10-16
CA2654408C (en) 2018-05-08
US20110008452A1 (en) 2011-01-13
EA200802440A1 (ru) 2009-06-30
IL246402A (en) 2017-12-31
IL195755A (en) 2016-07-31
JP2009539827A (ja) 2009-11-19
US9308259B2 (en) 2016-04-12
EP2395021A1 (en) 2011-12-14
EP2036574A4 (en) 2009-07-01
US20160159916A1 (en) 2016-06-09
KR20090024241A (ko) 2009-03-06
MX2008015621A (es) 2009-03-06
WO2007149010A1 (en) 2007-12-27

Similar Documents

Publication Publication Date Title
JP5687425B2 (ja) 肥満、真性糖尿病及び耐糖能異常を伴う疾患の治療用薬剤
JP2009539827A5 (https=)
AU2006340119B2 (en) Solid oral form of a medicinal preparation and a method for the production thereof
US20070141058A1 (en) Method of correcting immunopathological reactions and a medicament
EA029400B1 (ru) Фармацевтическая композиция для лечения ожирения и сопутствующих метаболических расстройств и способ лечения
AU723812B2 (en) Medicinal preparation and a method of medicinal action on human organism
CN101495143A (zh) 用于治疗肥胖、糖尿病和与受损的葡萄糖耐受性有关的疾病的药物制剂
US10213486B2 (en) Formulations of diluted amino acid segments and methods for making same
JP2022507646A (ja) ブレイアコニチンａの用途
RU2129005C1 (ru) Сбор для восстановления функции щитовидной железы
CN103272083A (zh) 用于预防和/或治疗哮喘的药物组合物、其制备方法及用途
JP5480139B2 (ja) 食欲制御用化合物
RU2437678C2 (ru) Лекарственное средство для перорального лечения ожирения и способ получения твердой лекарственной формы для пероральной терапии ожирения
CN103181945B (zh) 丝瓜子的用途
CN101549020B (zh) 无糖型枫蓼颗粒制剂、其用途及制备方法
RU2228198C1 (ru) Способ коррекции патологического аутоиммунного процесса при сахарном диабете
RU2245157C2 (ru) Биологически активная добавка для профилактики и лечения гриппа "фитогриппин"
Jin Adrenergic agonist therapy and emerging acupuncture targets in asthma: A review of mechanisms and therapeutic implications
CN118286156A (zh) 减重多肽药物组合物、鼻喷剂及其制备方法
RU2552221C2 (ru) Способ лечения ожирения и сопутствующих метаболических расстройств и лекарственное средство для лечения ожирения и сопутствующих метаболических расстройств
JPH02142732A (ja) 肥満並びに肥満に関連する各種疾患の治療剤
CN101380364A (zh) 用于糖尿病患者的草药产品及其生产方法
CN114163469A (zh) 美索巴莫磷酸钠新药族药品的剂型
Harika et al. SEMAGLUTIDE: A TRUE G
CN106491628A (zh) 一种治疗高血压的西药组合物

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100517

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120731

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121022

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20121029

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20130131

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20130131

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130903

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20131202

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140520

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140922

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20141110

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20150113

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20150122

R150 Certificate of patent or registration of utility model

Ref document number: 5687425

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees