JP5681875B2 - モジュラ経口摂取医薬品供給カプセル - Google Patents
モジュラ経口摂取医薬品供給カプセル Download PDFInfo
- Publication number
- JP5681875B2 JP5681875B2 JP2012504117A JP2012504117A JP5681875B2 JP 5681875 B2 JP5681875 B2 JP 5681875B2 JP 2012504117 A JP2012504117 A JP 2012504117A JP 2012504117 A JP2012504117 A JP 2012504117A JP 5681875 B2 JP5681875 B2 JP 5681875B2
- Authority
- JP
- Japan
- Prior art keywords
- capsule
- module
- foil
- compartment
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Inorganic Chemistry (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
Claims (12)
- 医薬品の供給のための経口摂取カプセルであって、
ある量の医薬品を含むための少なくとも1つの医薬品区画を備える第一モジュールを含み、前記医薬品区画は、フォイルによって封止され、
前記フォイルを破壊することによって前記医薬品区画を開放するよう、伝導性の加熱ワイヤに電気パルスをもたらすための電子機器を備える第二モジュールを含み、
前記加熱ワイヤは、前記フォイル内に埋設され、
前記第一モジュール及び前記第二モジュールは、前記加熱ワイヤが前記電子機器に電子的に結合されるよう、前記第一モジュールを前記第二モジュールに固定するための相互使用可能な接続手段を含む、
カプセル。 - 前記接続手段は、摺動接触を含む、請求項1に記載の経口摂取カプセル。
- 前記接続手段は、一組のピン及びソケットを含む、請求項1に記載の経口摂取カプセル。
- 前記接続手段は、ネジ山を含む、請求項1に記載の経口摂取カプセル。
- 前記電子機器は、前記電気パルスの強さを増大するために、少なくとも1つのコンデンサを含む、請求項1に記載の経口摂取カプセル。
- 前記医薬品区画の内壁は、粘着防止壁を備える、請求項1に記載の経口摂取カプセル。
- 前記フォイルは、プラスチックを含む、請求項1に記載の経口摂取カプセル。
- 前記プラスチックは、低密度ポリエチレン(LDPE)を含む、請求項6に記載の経口摂取カプセル。
- 前記フォイルは、ポリ塩化三弗化エチレン(PTCFE)を含む、請求項1に記載の経口摂取カプセル。
- 前記加熱ワイヤは、プリント導電性トレースである、請求項1に記載の経口摂取カプセル。
- 前記フォイルは、前記フォイルの破壊後に破壊する表示トレースを含む、請求項1に記載の経口摂取カプセル。
- 前記第一モジュールは、ある量の医薬品を含むための1つよりも多くの医薬品区画を含み、各医薬品区画は、埋設された伝導性の加熱ワイヤを備える分離フォイルによって封止され、前記接続手段は、前記加熱ワイヤの各1つを前記電子機器に別個に結合するよう配置される、請求項1に記載の経口摂取カプセル。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16724009P | 2009-04-07 | 2009-04-07 | |
US61/167,240 | 2009-04-07 | ||
PCT/IB2010/051453 WO2010116312A1 (en) | 2009-04-07 | 2010-04-02 | Modular ingestible drug delivery capsule |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2012522616A JP2012522616A (ja) | 2012-09-27 |
JP5681875B2 true JP5681875B2 (ja) | 2015-03-11 |
Family
ID=42935694
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012504117A Expired - Fee Related JP5681875B2 (ja) | 2009-04-07 | 2010-04-02 | モジュラ経口摂取医薬品供給カプセル |
Country Status (7)
Country | Link |
---|---|
US (1) | US9744139B2 (ja) |
EP (1) | EP2416834B1 (ja) |
JP (1) | JP5681875B2 (ja) |
KR (1) | KR20120006040A (ja) |
CN (1) | CN102481437B (ja) |
BR (1) | BRPI1006765A2 (ja) |
WO (1) | WO2010116312A1 (ja) |
Families Citing this family (13)
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US10045713B2 (en) | 2012-08-16 | 2018-08-14 | Rock West Medical Devices, Llc | System and methods for triggering a radiofrequency transceiver in the human body |
EP2884893A1 (en) | 2012-08-16 | 2015-06-24 | Rock West Solutions, Inc. | System and methods for locating a radiofrequency transceiver in the human body |
WO2014053352A1 (en) | 2012-10-03 | 2014-04-10 | Danmarks Tekniske Universitet | Ingestible capsule for remote controlled release of a substance |
WO2015061343A1 (en) | 2013-10-22 | 2015-04-30 | Rock West Solutions, Inc. | System to localize swallowable pill sensor with three transmitting elements |
US11541015B2 (en) | 2017-05-17 | 2023-01-03 | Massachusetts Institute Of Technology | Self-righting systems, methods, and related components |
CA3063426A1 (en) | 2017-05-17 | 2018-11-22 | Massachusetts Institute Of Technology | Tissue anchoring articles |
EP3793667A1 (en) | 2018-05-17 | 2021-03-24 | Massachusetts Institute of Technology | Systems for electrical stimulation |
CN108686292A (zh) * | 2018-05-28 | 2018-10-23 | 重庆大学 | 一种释药胶囊 |
GB201900780D0 (en) * | 2019-01-21 | 2019-03-06 | Vibrant Ltd | Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user |
CN113993560B (zh) | 2019-02-01 | 2024-05-07 | 麻省理工学院 | 用于液体注射的系统和方法 |
EP3976134A4 (en) | 2019-05-29 | 2023-06-28 | Incube Labs, Llc | Devices and methods for administering a therapeutic preparation |
CN110694166B (zh) * | 2019-10-15 | 2021-09-28 | 马也 | 一种肠内给药系统 |
US11541216B2 (en) | 2019-11-21 | 2023-01-03 | Massachusetts Institute Of Technology | Methods for manufacturing tissue interfacing components |
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-
2010
- 2010-04-02 EP EP10717240.5A patent/EP2416834B1/en not_active Not-in-force
- 2010-04-02 JP JP2012504117A patent/JP5681875B2/ja not_active Expired - Fee Related
- 2010-04-02 WO PCT/IB2010/051453 patent/WO2010116312A1/en active Application Filing
- 2010-04-02 US US13/262,841 patent/US9744139B2/en active Active
- 2010-04-02 BR BRPI1006765A patent/BRPI1006765A2/pt not_active IP Right Cessation
- 2010-04-02 KR KR1020117026311A patent/KR20120006040A/ko not_active Application Discontinuation
- 2010-04-02 CN CN201080015953.5A patent/CN102481437B/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2012522616A (ja) | 2012-09-27 |
US20120116358A1 (en) | 2012-05-10 |
EP2416834A1 (en) | 2012-02-15 |
WO2010116312A1 (en) | 2010-10-14 |
BRPI1006765A2 (pt) | 2019-03-26 |
CN102481437A (zh) | 2012-05-30 |
EP2416834B1 (en) | 2013-10-16 |
US9744139B2 (en) | 2017-08-29 |
CN102481437B (zh) | 2014-04-30 |
KR20120006040A (ko) | 2012-01-17 |
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