JP5675850B2 - ヘタリール−［１，８］ナフチリジン誘導体 - Google Patents
ヘタリール−［１，８］ナフチリジン誘導体 Download PDFInfo
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- JP5675850B2 JP5675850B2 JP2012551506A JP2012551506A JP5675850B2 JP 5675850 B2 JP5675850 B2 JP 5675850B2 JP 2012551506 A JP2012551506 A JP 2012551506A JP 2012551506 A JP2012551506 A JP 2012551506A JP 5675850 B2 JP5675850 B2 JP 5675850B2
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- phenyl
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- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07D—HETEROCYCLIC COMPOUNDS
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Landscapes
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| EP10001251.7 | 2010-02-05 | ||
| EP10001251 | 2010-02-05 | ||
| PCT/EP2010/007743 WO2011095196A1 (en) | 2010-02-05 | 2010-12-17 | Hetaryl-[1,8]naphthyridine derivatives |
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| WO2011101069A2 (en) * | 2010-02-22 | 2011-08-25 | Merck Patent Gmbh | Hetarylaminonaphthyridines |
| CN102958930B (zh) * | 2010-06-28 | 2018-04-27 | 默克专利有限公司 | 作为用于对抗癌症的激酶抑制剂的2,4-二芳基取代的[1,8]二氮杂萘化合物 |
| UA112758C2 (uk) * | 2010-07-07 | 2016-10-25 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб введення молекули функціоналізованої лінійної нуклеотидної касети у клітину, що містить клітинну стінку |
| KR20130118612A (ko) * | 2012-04-20 | 2013-10-30 | (주)네오믹스 | 신규한 아미노피리딘 유도체 및 이의 용도 |
| US9550750B2 (en) | 2012-10-05 | 2017-01-24 | Merck Sharp & Dohme Corp. | Indoline compounds as aldosterone synthase inhibitors |
| CA2887203A1 (en) | 2012-10-05 | 2014-04-10 | Rigel Pharmaceuticals, Inc. | 2,3-(hetero)aryl substituted pyridinyl compounds and their use as gdf-8 inhibitors |
| MA38287B1 (fr) | 2013-01-23 | 2018-08-31 | Astrazeneca Ab | Nouveaux dérivés aminopyrazine pour le traitement ou la prévention du cancer |
| CN103113369A (zh) * | 2013-03-21 | 2013-05-22 | 云南大学 | 一种具有抗肿瘤活性的苯并[b][1,8]-萘啶-2-(1H)-亚胺衍生物及合成方法 |
| TWI529171B (zh) * | 2013-07-29 | 2016-04-11 | 赫孚孟拉羅股份公司 | １，７－萘啶衍生物 |
| AU2014354711B2 (en) | 2013-11-27 | 2018-10-25 | Signalchem Lifesciences Corporation | Aminopyridine derivatives as TAM family kinase inhibitors |
| TN2016000270A1 (en) | 2014-01-14 | 2017-10-06 | Millennium Pharm Inc | Heteroaryls and uses thereof. |
| EP3094326A4 (en) | 2014-01-14 | 2017-07-26 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| US10233170B2 (en) * | 2014-04-08 | 2019-03-19 | Rigel Pharmaceuticals, Inc. | 2,3-disubstituted pyridine compounds as TGF-beta inhibitors and methods of use |
| IL277071B2 (en) | 2018-03-08 | 2024-07-01 | Incyte Corp | AMINOPYRAZINE DIOL COMPOUNDS AS PI3K-y INHIBITORS |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| JP2023509760A (ja) | 2020-01-08 | 2023-03-09 | シンシス セラピューティクス，インコーポレイテッド | Ａｌｋ５阻害剤複合体およびその使用 |
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| EP1187633A4 (en) | 1999-04-08 | 2005-05-11 | Arch Dev Corp | USE OF ANTI-VEGF ANTIBODIES TO ENHANCE RADIATION IN ANTICANCER THERAPY |
| GB0117060D0 (en) * | 2001-07-12 | 2001-09-05 | Merck Sharp & Dohme | Therapeutic agents |
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- 2010-12-17 US US13/574,282 patent/US8614226B2/en active Active
- 2010-12-17 ES ES10794897.8T patent/ES2667049T3/es active Active
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- 2010-12-17 EP EP10794897.8A patent/EP2531500B1/en not_active Not-in-force
- 2010-12-17 MX MX2012008550A patent/MX2012008550A/es not_active Application Discontinuation
- 2010-12-17 CA CA2789021A patent/CA2789021C/en not_active Expired - Fee Related
- 2010-12-17 EA EA201201081A patent/EA201201081A1/ru unknown
- 2010-12-17 CN CN201080063064.6A patent/CN102741249B/zh not_active Expired - Fee Related
- 2010-12-17 KR KR1020127022601A patent/KR20120124469A/ko not_active Withdrawn
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| Publication number | Publication date |
|---|---|
| ZA201206630B (en) | 2013-05-29 |
| CN102741249A (zh) | 2012-10-17 |
| BR112012018954A2 (pt) | 2016-04-12 |
| CA2789021C (en) | 2018-02-06 |
| JP2013518832A (ja) | 2013-05-23 |
| KR20120124469A (ko) | 2012-11-13 |
| WO2011095196A1 (en) | 2011-08-11 |
| US20120295902A1 (en) | 2012-11-22 |
| ES2667049T3 (es) | 2018-05-09 |
| MX2012008550A (es) | 2012-09-07 |
| CN102741249B (zh) | 2015-11-25 |
| US20140038960A1 (en) | 2014-02-06 |
| US8614226B2 (en) | 2013-12-24 |
| AU2010344973B2 (en) | 2016-06-16 |
| CA2789021A1 (en) | 2011-08-11 |
| AU2010344973A1 (en) | 2012-09-20 |
| EA201201081A1 (ru) | 2013-03-29 |
| EP2531500A1 (en) | 2012-12-12 |
| SG182803A1 (en) | 2012-09-27 |
| US8912216B2 (en) | 2014-12-16 |
| EP2531500B1 (en) | 2018-01-24 |
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