JP5623400B2 - 直径10〜20μmのマイクロスフェアを含む非経口組成物 - Google Patents

直径10〜20μmのマイクロスフェアを含む非経口組成物 Download PDF

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JP5623400B2
JP5623400B2 JP2011521575A JP2011521575A JP5623400B2 JP 5623400 B2 JP5623400 B2 JP 5623400B2 JP 2011521575 A JP2011521575 A JP 2011521575A JP 2011521575 A JP2011521575 A JP 2011521575A JP 5623400 B2 JP5623400 B2 JP 5623400B2
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ヒナール,ベルナルド ナダル
ヒナール,ベルナルド ナダル
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コアセラピクス エスエルユー
コアセラピクス エスエルユー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1833Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P13/10Drugs for disorders of the urinary system of the bladder
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00Drugs for disorders of the cardiovascular system
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  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011521575A 2008-08-05 2009-08-05 直径10〜20μmのマイクロスフェアを含む非経口組成物 Expired - Fee Related JP5623400B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0814302.6 2008-08-05
GBGB0814302.6A GB0814302D0 (en) 2008-08-05 2008-08-05 Compounds and methods
PCT/EP2009/060171 WO2010015665A2 (en) 2008-08-05 2009-08-05 Compounds and methods

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JP2011529946A JP2011529946A (ja) 2011-12-15
JP2011529946A5 JP2011529946A5 (https=) 2012-08-30
JP5623400B2 true JP5623400B2 (ja) 2014-11-12

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US (3) US20120195939A1 (https=)
EP (1) EP2323626B1 (https=)
JP (1) JP5623400B2 (https=)
KR (1) KR101639827B1 (https=)
CN (1) CN102170868A (https=)
AU (1) AU2009279086B2 (https=)
BR (1) BRPI0917571B1 (https=)
CA (1) CA2732785C (https=)
CL (1) CL2011000244A1 (https=)
ES (1) ES2677005T3 (https=)
GB (1) GB0814302D0 (https=)
MX (1) MX2011001261A (https=)
WO (1) WO2010015665A2 (https=)

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Publication number Publication date
BRPI0917571A2 (pt) 2020-08-11
AU2009279086B2 (en) 2014-05-22
KR20110051212A (ko) 2011-05-17
AU2009279086A1 (en) 2010-02-11
ES2677005T3 (es) 2018-07-27
CN102170868A (zh) 2011-08-31
US20130189321A1 (en) 2013-07-25
CL2011000244A1 (es) 2011-07-15
US20130315997A1 (en) 2013-11-28
JP2011529946A (ja) 2011-12-15
US8846099B2 (en) 2014-09-30
EP2323626A2 (en) 2011-05-25
BRPI0917571B1 (pt) 2022-01-04
CA2732785A1 (en) 2010-02-11
WO2010015665A2 (en) 2010-02-11
KR101639827B1 (ko) 2016-07-14
GB0814302D0 (en) 2008-10-01
CA2732785C (en) 2016-11-22
MX2011001261A (es) 2011-08-08
US20120195939A1 (en) 2012-08-02
WO2010015665A3 (en) 2010-10-07
EP2323626B1 (en) 2018-04-11

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