JP5616449B2 - ナノ抗体を発現するトランスジェニックイネ - Google Patents
ナノ抗体を発現するトランスジェニックイネ Download PDFInfo
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- JP5616449B2 JP5616449B2 JP2012525370A JP2012525370A JP5616449B2 JP 5616449 B2 JP5616449 B2 JP 5616449B2 JP 2012525370 A JP2012525370 A JP 2012525370A JP 2012525370 A JP2012525370 A JP 2012525370A JP 5616449 B2 JP5616449 B2 JP 5616449B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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| JP2012525370A JP5616449B2 (ja) | 2010-07-20 | 2011-07-08 | ナノ抗体を発現するトランスジェニックイネ |
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| JP2010162630 | 2010-07-20 | ||
| PCT/JP2011/065670 WO2012011396A1 (fr) | 2010-07-20 | 2011-07-08 | Plant de riz transgénique capable d'exprimer des nano-anticorps |
| JP2012525370A JP5616449B2 (ja) | 2010-07-20 | 2011-07-08 | ナノ抗体を発現するトランスジェニックイネ |
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| WO (1) | WO2012011396A1 (fr) |
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| AU2014273418B2 (en) * | 2013-04-29 | 2020-04-23 | Biotalys NV | Agrochemical compositions comprising antibodies binding to sphingolipids |
| US10858666B2 (en) | 2014-11-05 | 2020-12-08 | Biotalys | Transgenic plants expressing a variable domain of a heavy chain antibody (VHH) that binds to a sphingolipid of a fungus |
| EP3604540A4 (fr) * | 2017-03-31 | 2020-12-23 | The University of Tokyo | Anticorps de norovirus |
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| WO2004074491A2 (fr) * | 2003-02-18 | 2004-09-02 | Syngeta Participations Ag | Expression dans des plantes d'anticorps contre l'escherichia coli entero-toxigene |
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| WO2004074491A2 (fr) * | 2003-02-18 | 2004-09-02 | Syngeta Participations Ag | Expression dans des plantes d'anticorps contre l'escherichia coli entero-toxigene |
Non-Patent Citations (3)
| Title |
|---|
| JPN6014025540; ＴＥＨ，Ｙ．Ｈ． ＡＮＤ ＫＡＶＡＮＡＧＨ，Ｔ．Ａ．: 'Ｈｉｇｈ-ｌｅｖｅｌ ｅｘｐｒｅｓｓｉｏｎ ｏｆ Ｃａｍｅｌｉｄ ｎａｎｏｂｏｄｉｅｓ ｉｎ Ｎｉｃｏｔｉａｎａ ｂｅｎｔｈａｍｉａｎａ．' Ｔｒａｎｓｇｅｎｉｃ Ｒｅｓ． Ｖｏｌ．１９， Ｎｏ．４, 20091028, ｐｐ．５７５-８６ * |
| JPN6014025542; ＷＩＮＩＣＨＡＹＡＫＵＬ，Ｓ． ｅｔ ａｌ．: 'Ｈｅａｄ-ｔｏ-ｔａｉｌ ｆｕｓｉｏｎｓ ｏｆ ｃａｍｅｌｉｄ ａｎｔｉｂｏｄｉｅｓ ｃａｎ ｂｅ ｅｘｐｒｅｓｓｅｄ ｉｎ ｐｌａｎｔａ ａｎｄ ｂｉｎｄ ｉｎ ｒｕｍｅｎ ｆｌｕｉｄ．' Ｂｉｏｔｅｃｈｎｏｌ． Ａｐｐｌ． Ｂｉｏｃｈｅｍ． Ｖｏｌ．５３， Ｎｏ．２, 200906, ｐｐ．１１１-２２ * |
| JPN6014025544; ＡＢＥ，Ｍ． ｅｔ ａｌ．: 'Ａ ｒｉｃｅ-ｂａｓｅｄ ｓｏｌｕｂｌｅ ｆｏｒｍ ｏｆ ａ ｍｕｒｉｎｅ ＴＮＦ-ｓｐｅｃｉｆｉｃ ｌｌａｍａ ｖａｒｉａｂｌｅ ｄｏｍａｉｎ ｏｆ ｈｅａｖｙ-ｃｈａｉｎ ａｎｔｉｂｏｄｙ ｓｕｐ' Ｊ． Ｂｉｏｔｅｃｈｎｏｌ． Ｖｏｌ．１７５, 20140410, ｐｐ．４５-５２ * |
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| WO2012011396A1 (fr) | 2012-01-26 |
| JPWO2012011396A1 (ja) | 2013-09-09 |
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