JP5612801B2 - 上皮幹細胞の増殖方法 - Google Patents

上皮幹細胞の増殖方法 Download PDF

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Publication number
JP5612801B2
JP5612801B2 JP2001577863A JP2001577863A JP5612801B2 JP 5612801 B2 JP5612801 B2 JP 5612801B2 JP 2001577863 A JP2001577863 A JP 2001577863A JP 2001577863 A JP2001577863 A JP 2001577863A JP 5612801 B2 JP5612801 B2 JP 5612801B2
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Prior art keywords
epithelial stem
stem cells
amniotic membrane
amniotic
surgical
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Expired - Fee Related
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JP2001577863A
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English (en)
Japanese (ja)
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JP2003532466A5 (enExample
JP2003532466A (ja
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ツァイ,レイ・ジュイ−ファン
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Publication of JP2003532466A5 publication Critical patent/JP2003532466A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/142Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813Epithelial cells, e.g. keratinocytes, urothelial cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/90Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92Amnion; Decellularised dermis or mucosa

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Vascular Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2001577863A 2000-04-27 2001-04-25 上皮幹細胞の増殖方法 Expired - Fee Related JP5612801B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20003600P 2000-04-27 2000-04-27
US60/200,036 2000-04-27
PCT/US2001/013321 WO2001080760A1 (en) 2000-04-27 2001-04-25 Method for expansion of epithelial stem cells

Publications (3)

Publication Number Publication Date
JP2003532466A JP2003532466A (ja) 2003-11-05
JP2003532466A5 JP2003532466A5 (enExample) 2007-12-27
JP5612801B2 true JP5612801B2 (ja) 2014-10-22

Family

ID=22740051

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001577863A Expired - Fee Related JP5612801B2 (ja) 2000-04-27 2001-04-25 上皮幹細胞の増殖方法

Country Status (11)

Country Link
EP (1) EP1276431B1 (enExample)
JP (1) JP5612801B2 (enExample)
CN (1) CN1296102C (enExample)
AT (1) ATE329632T1 (enExample)
AU (2) AU5380201A (enExample)
CA (1) CA2406282C (enExample)
DE (1) DE60120676T2 (enExample)
ES (1) ES2266193T3 (enExample)
PT (1) PT1276431E (enExample)
TW (1) TW506827B (enExample)
WO (1) WO2001080760A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1454600B1 (en) * 2001-11-19 2011-08-31 ArBlast Co., Ltd. Ectocornea-like sheet and method of constructing the same
KR101203434B1 (ko) * 2003-02-06 2012-11-21 가부시키가이샤 셀시드 전안부 관련 세포 시트, 3 차원 구조체, 및 그들의 제조법
CN1747753B (zh) 2003-02-06 2010-11-10 赛尔斯德株式会社 用于形成角膜上皮的细胞片、及其制造方法和使用方法
US20050186672A1 (en) * 2004-01-27 2005-08-25 Reliance Life Sciences Pvt. Ltd. Tissue system with undifferentiated stem cells derived from corneal limbus
CA2559585A1 (en) * 2004-03-11 2005-09-22 Arblast Co., Ltd. Biological tissue sheet, method of forming the same and transplantation method by using the sheet
JP4576545B2 (ja) * 2004-05-27 2010-11-10 独立行政法人理化学研究所 羊膜由来因子による胚性幹細胞の培養方法
CN100336567C (zh) * 2004-10-19 2007-09-12 北京科宇联合干细胞生物技术有限公司 医用角膜贴片
KR20070093991A (ko) * 2005-01-14 2007-09-19 아르브라스트 가부시키가이샤 양막을 이용한 시트형 조성물 및 그 제작 방법
JP4863655B2 (ja) * 2005-06-17 2012-01-25 国立大学法人 東京医科歯科大学 細胞含有シート
TWI407967B (zh) * 2006-04-28 2013-09-11 Ray Jui Fang Tsai 人類角膜內皮幹細胞之擴增方法
CN102166375B (zh) * 2011-02-16 2013-04-10 中国海洋大学 一种组织工程人角膜上皮的重建方法
CN103007349B (zh) * 2012-12-13 2014-07-09 吉林省拓华生物科技有限公司 负载干细胞的大面积羊膜贴片的制备方法
CN115671398B (zh) * 2022-11-22 2024-03-01 首都医科大学附属北京同仁医院 一种3d打印仿生角膜缘移植物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47062A (en) * 1975-04-10 1979-07-25 Yeda Res & Dev Process for diminishing antigenicity of tissues to be usedas transplants by treatment with glutaraldehyde
JPS63260549A (ja) * 1987-04-17 1988-10-27 石川 統一 補綴材料およびその製造方法
US5135915A (en) * 1988-10-14 1992-08-04 Genentech, Inc. Method for the treatment of grafts prior to transplantation using TGF-.beta.
JP2905719B2 (ja) * 1995-03-31 1999-06-14 東洋紡績株式会社 複合医用材料
US6152142A (en) * 1997-02-28 2000-11-28 Tseng; Scheffer C. G. Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries
US5932205A (en) * 1997-07-24 1999-08-03 Wang; Ming X. Biochemical contact lens for treating photoablated corneal tissue

Also Published As

Publication number Publication date
DE60120676T2 (de) 2007-05-24
TW506827B (en) 2002-10-21
WO2001080760A1 (en) 2001-11-01
CA2406282C (en) 2012-06-12
ES2266193T3 (es) 2007-03-01
JP2003532466A (ja) 2003-11-05
EP1276431A4 (en) 2003-08-06
HK1056989A1 (en) 2004-03-12
ATE329632T1 (de) 2006-07-15
AU2001253802B2 (en) 2006-11-30
CA2406282A1 (en) 2001-11-01
CN1296102C (zh) 2007-01-24
AU5380201A (en) 2001-11-07
CN1426289A (zh) 2003-06-25
DE60120676D1 (de) 2006-07-27
PT1276431E (pt) 2006-11-30
WO2001080760A8 (en) 2003-05-30
EP1276431B1 (en) 2006-06-14
EP1276431A1 (en) 2003-01-22

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