JP5603852B2 - 凍結乾燥ナノエマルション - Google Patents
凍結乾燥ナノエマルション Download PDFInfo
- Publication number
- JP5603852B2 JP5603852B2 JP2011500060A JP2011500060A JP5603852B2 JP 5603852 B2 JP5603852 B2 JP 5603852B2 JP 2011500060 A JP2011500060 A JP 2011500060A JP 2011500060 A JP2011500060 A JP 2011500060A JP 5603852 B2 JP5603852 B2 JP 5603852B2
- Authority
- JP
- Japan
- Prior art keywords
- nanoemulsion
- lyophilized
- emulsion
- fatty acid
- lipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008015366.4 | 2008-03-20 | ||
| DE102008015366A DE102008015366A1 (de) | 2008-03-20 | 2008-03-20 | Lyophilisierte Nanoemulsion |
| PCT/EP2009/001355 WO2009115175A2 (de) | 2008-03-20 | 2009-02-26 | Lyophilisierte nanoemulsion |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011519349A JP2011519349A (ja) | 2011-07-07 |
| JP2011519349A5 JP2011519349A5 (enExample) | 2014-03-13 |
| JP5603852B2 true JP5603852B2 (ja) | 2014-10-08 |
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|---|---|---|---|
| JP2011500060A Expired - Fee Related JP5603852B2 (ja) | 2008-03-20 | 2009-02-26 | 凍結乾燥ナノエマルション |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8211948B2 (enExample) |
| EP (1) | EP2252267B1 (enExample) |
| JP (1) | JP5603852B2 (enExample) |
| AU (1) | AU2009226618B2 (enExample) |
| CA (1) | CA2718791C (enExample) |
| DE (1) | DE102008015366A1 (enExample) |
| ES (1) | ES2608062T3 (enExample) |
| IL (1) | IL207913A (enExample) |
| WO (1) | WO2009115175A2 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8357639B2 (en) * | 2007-07-03 | 2013-01-22 | Baker Hughes Incorporated | Nanoemulsions |
| MX2010010050A (es) | 2008-03-20 | 2011-03-15 | Virun Inc Star | Emulsiones que incluyen un derivado de polietilen glicol de tocoferol. |
| CN103190631B (zh) | 2008-03-20 | 2016-01-20 | 维尔恩公司 | 非水性预乳液组合物及制备包含植物甾醇的饮料的方法 |
| EP2563164B1 (en) * | 2010-03-23 | 2016-06-29 | Virun, Inc. | Nanoemulsion including sucrose fatty acid ester |
| US8741373B2 (en) | 2010-06-21 | 2014-06-03 | Virun, Inc. | Compositions containing non-polar compounds |
| US8586527B2 (en) | 2011-10-20 | 2013-11-19 | Jaipal Singh | Cerivastatin to treat pulmonary disorders |
| BR112014018110B1 (pt) | 2012-01-23 | 2022-06-07 | Sage Therapeutics, Inc | Composições farmacêutica aquosas formuladas para administração parenteral e uso de alopregnanolona e sulfobutiléter-b-ciclodextrina |
| CA2863544C (en) | 2012-02-10 | 2019-03-26 | Virun, Inc. | Beverage compositions containing non-polar compounds |
| IL294306B2 (en) | 2012-08-21 | 2024-01-01 | Sage Therapeutics Inc | Methods of treating epilepsy or status epilepticus |
| US9351517B2 (en) | 2013-03-15 | 2016-05-31 | Virun, Inc. | Formulations of water-soluble derivatives of vitamin E and compositions containing same |
| US9693574B2 (en) | 2013-08-08 | 2017-07-04 | Virun, Inc. | Compositions containing water-soluble derivatives of vitamin E mixtures and modified food starch |
| US9861611B2 (en) | 2014-09-18 | 2018-01-09 | Virun, Inc. | Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same |
| US10016363B2 (en) | 2014-09-18 | 2018-07-10 | Virun, Inc. | Pre-spray emulsions and powders containing non-polar compounds |
| US20220023209A1 (en) * | 2018-12-06 | 2022-01-27 | Lipicare Life Sciences Ltd. | Vitamin d micro-emulsioins and uses thereof |
| JP7756548B2 (ja) * | 2021-11-30 | 2025-10-20 | 株式会社ダイセル | ガス発生器 |
| CN116650425B (zh) * | 2023-07-13 | 2025-06-27 | 晟迪生物医药(苏州)有限公司 | 糖酯化合物或其盐在冷冻保护、冷冻干燥保护中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5296724A (en) | 1976-02-10 | 1977-08-13 | Kyowa Hakko Kogyo Co Ltd | Preparation of powdery products |
| FR2561916B1 (fr) * | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
| JPH04275216A (ja) * | 1991-03-04 | 1992-09-30 | Eisai Co Ltd | 脂溶性薬物を含有した凍結乾燥組成物 |
| DE4244122C1 (de) | 1992-12-24 | 1994-06-01 | Sanol Arznei Schwarz Gmbh | Lyophilisierte, wirkstoffhaltige Emulsion zur intravenösen Applikation |
| US5646082A (en) | 1993-06-24 | 1997-07-08 | Cosmo Research Institute | Crystalline aluminosilicate, process for producing the same, and catalyst employing the same for catalytic cracking of hydrocarbon oil |
| US5948002A (en) * | 1996-11-15 | 1999-09-07 | Bonutti; Peter M. | Apparatus and method for use in positioning a suture anchor |
| US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| JPH11171796A (ja) | 1997-12-08 | 1999-06-29 | Ohta Pharmaceut Co Ltd | テプレノン経口投与用製剤およびその製造方法 |
| FR2800611B1 (fr) * | 1999-11-08 | 2002-10-11 | Oreal | Composition a application topique contenant un sucre, et ses utilisations cosmetiques |
| WO2002087692A1 (en) | 2001-04-26 | 2002-11-07 | The Procter & Gamble Company | A method and apparatus for the treatment of cosmetic skin conditioins |
| JP2004161650A (ja) | 2002-11-12 | 2004-06-10 | Taisho Pharmaceut Co Ltd | Ｗ／ｏ／ｗ型ドライエマルション |
| EP1598060A1 (en) * | 2004-05-18 | 2005-11-23 | Nestec S.A. | Oil-in-water emulsion for delivery |
| US8388950B2 (en) * | 2005-06-15 | 2013-03-05 | Kaneka Corporation | Coenzyme Q10-containing water-soluble composition and process for production thereof |
| FR2901124B1 (fr) * | 2006-05-17 | 2008-06-27 | Oreal | Emulsion huile dans eau fine |
| JP2008142588A (ja) * | 2006-12-06 | 2008-06-26 | Fujifilm Corp | 水中油滴型エマルション及びその製造方法、並びに機能性粉末及びその製造方法 |
| CN101428002A (zh) * | 2008-11-20 | 2009-05-13 | 沈阳万爱普利德医药科技有限公司 | 注射用紫杉醇冻干微乳剂及其制备方法 |
-
2008
- 2008-03-20 DE DE102008015366A patent/DE102008015366A1/de not_active Withdrawn
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2009
- 2009-02-26 WO PCT/EP2009/001355 patent/WO2009115175A2/de not_active Ceased
- 2009-02-26 US US12/922,787 patent/US8211948B2/en not_active Expired - Fee Related
- 2009-02-26 ES ES09722255.8T patent/ES2608062T3/es active Active
- 2009-02-26 EP EP09722255.8A patent/EP2252267B1/de active Active
- 2009-02-26 CA CA2718791A patent/CA2718791C/en active Active
- 2009-02-26 AU AU2009226618A patent/AU2009226618B2/en not_active Ceased
- 2009-02-26 JP JP2011500060A patent/JP5603852B2/ja not_active Expired - Fee Related
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2010
- 2010-08-31 IL IL207913A patent/IL207913A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009115175A2 (de) | 2009-09-24 |
| IL207913A0 (en) | 2010-12-30 |
| AU2009226618A1 (en) | 2009-09-24 |
| JP2011519349A (ja) | 2011-07-07 |
| CA2718791C (en) | 2016-03-29 |
| DE102008015366A1 (de) | 2009-09-24 |
| US20110015266A1 (en) | 2011-01-20 |
| AU2009226618B2 (en) | 2014-04-10 |
| IL207913A (en) | 2015-05-31 |
| WO2009115175A3 (de) | 2010-01-07 |
| US8211948B2 (en) | 2012-07-03 |
| ES2608062T3 (es) | 2017-04-05 |
| EP2252267A2 (de) | 2010-11-24 |
| EP2252267B1 (de) | 2016-09-28 |
| CA2718791A1 (en) | 2009-09-24 |
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