JP5599972B2 - 口腔疾患予防用処方物 - Google Patents
口腔疾患予防用処方物 Download PDFInfo
- Publication number
- JP5599972B2 JP5599972B2 JP2008513398A JP2008513398A JP5599972B2 JP 5599972 B2 JP5599972 B2 JP 5599972B2 JP 2008513398 A JP2008513398 A JP 2008513398A JP 2008513398 A JP2008513398 A JP 2008513398A JP 5599972 B2 JP5599972 B2 JP 5599972B2
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- toothpaste
- glycerophosphate
- bromelain
- magnesium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
2.75〜78℃と計測されるまで必要量の水を加熱し、次いで、水を撹拌器に入れる。
3.その水に、サッカリン酸ナトリウム、キシリトール、パラベン、塩化マグネシウム(又は、実施例3ではグリセロリン酸マグネシウム)を加える。透明な溶液が形成されるように混合する。
4.得られた溶液に構成要素のグリセロール懸濁液を加える(ポイント1.1を参照のこと)。均質な塊が形成されるように混合する。
5.10分間、脱気及び混合することにより、混合物を完全に脱気する。
6.二酸化チタンを撹拌器に加える。
7.10分間、脱気及び混合することにより、混合物を完全に脱気する。
8.シリカを撹拌器に加える。
9.30〜40分間、脱気及び混合する。
10.ホモジナイズポンプ(homogenizing pump)を用いて15〜20分間、練り歯磨き剤を均質化する。
11.練り歯磨き剤を混合しながら40〜45℃まで冷却する。
12.ブロメラインを残りのグリセロールに加え、均質な塊が形成されるまで混合する。
13.1/3のグリセロール中のブロメライン懸濁液を撹拌器に入れ、均質な塊が形成されるまで20分間混合する。
14.香料及びラウリル硫酸ナトリウム(又は実施例1ではアミドプロピルベタイン)を加える。
15.均質な塊が形成されるまで30分間ペースト状物を混合する。
製造方法及び操作順序は、全ての処方物の実施例で同様である。
Claims (1)
- グリセロール、シリカ、グリセロリン酸カルシウム、メチルパラベン、プロピルパラベン、二酸化チタン、香料、サッカリンナトリウム、ラウリル硫酸ナトリウム又はアルキルアミドベタイン及び飲料水を含んでなる、練り歯磨きの形態の口腔疾患予防用処方物であって、更にタンパク分解性酵素ブロメライン、天然甘味料キシリトール、キサンタンガム及び塩化マグネシウム又はグリセロリン酸マグネシウムを以下の質量%の配合量;グリセロール:20−25、キシリトール:10−14、シリカ:22−26、キサンタンガム:1.2−1.4、メチルパラベン:0.2−0.3、プロピルパラベン:0.08−0.12、サッカリンナトリウム:0.1−0.3、二酸化チタン:0.2−0.4、香料:0.7−1.0、ブロメライン:0.1−0.7、ラウリル硫酸ナトリウム:1.2−1.4又はアルキルアミドベタイン:1.2、グリセロリン酸カルシウム:0.6−1.0、塩化マグネシウム:0.08−0.16又はグリセロリン酸マグネシウム:0.16、及び水:100質量%に達する量、で含むことを特徴とする前記口腔疾患予防用処方物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2005115513/15A RU2293551C1 (ru) | 2005-05-23 | 2005-05-23 | Состав для профилактики заболеваний полости рта |
RU2005115513 | 2005-05-23 | ||
PCT/RU2005/000600 WO2006130040A1 (en) | 2005-05-23 | 2005-11-25 | Formulation for prophylaxis of oral cavity diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008542264A JP2008542264A (ja) | 2008-11-27 |
JP5599972B2 true JP5599972B2 (ja) | 2014-10-01 |
Family
ID=37481886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008513398A Active JP5599972B2 (ja) | 2005-05-23 | 2005-11-25 | 口腔疾患予防用処方物 |
Country Status (18)
Country | Link |
---|---|
US (1) | US8460643B2 (ja) |
EP (1) | EP1895996B1 (ja) |
JP (1) | JP5599972B2 (ja) |
KR (1) | KR20080067284A (ja) |
CN (1) | CN101365418B (ja) |
CY (1) | CY1116465T1 (ja) |
DK (1) | DK1895996T3 (ja) |
EA (1) | EA011229B1 (ja) |
ES (1) | ES2541781T3 (ja) |
HR (1) | HRP20150690T1 (ja) |
HU (1) | HUE025691T2 (ja) |
NO (1) | NO337434B1 (ja) |
PL (1) | PL1895996T3 (ja) |
PT (1) | PT1895996E (ja) |
RU (1) | RU2293551C1 (ja) |
SI (1) | SI1895996T1 (ja) |
UA (1) | UA83328C2 (ja) |
WO (1) | WO2006130040A1 (ja) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA011286B1 (ru) * | 2007-08-29 | 2009-02-27 | Общество С Ограниченной Ответственностью "Вдс" | Таблетка для профилактики и лечения заболеваний зубов и пародонта |
EA011254B1 (ru) * | 2008-02-07 | 2009-02-27 | Общество С Ограниченной Ответственностью "Вдс" | Гель для реминерализации тканей зубов |
EA012247B1 (ru) * | 2008-07-07 | 2009-08-28 | Общество С Ограниченной Ответственностью "Вдс" | Лечебно-профилактический состав для ухода за полостью рта |
CN102231975A (zh) * | 2008-09-24 | 2011-11-02 | 格雷斯股份有限两合公司 | 组合物、口腔护理产品及其制备和使用方法 |
US8741268B2 (en) * | 2009-09-10 | 2014-06-03 | Preventive Technologies, Inc. | Dental prophylactic paste |
FR3024019B1 (fr) * | 2014-07-28 | 2017-11-24 | Yvan Erbs | Complement alimentaire pour ameliorer le fonctionnement des cellules vivantes et procede associe |
FR3070856A1 (fr) * | 2017-09-11 | 2019-03-15 | Yvan ERBS | Produit de soin pour reduire les risques de survenance d'au moins une maladie ou un trouble de la sante |
CN108653174A (zh) * | 2018-07-11 | 2018-10-16 | 杭州纳美智康科技有限公司 | 一种含银耳多糖的牙膏及其制备方法 |
WO2021127674A1 (en) | 2019-12-16 | 2021-06-24 | Colgate-Palmolive Company | Oral care compositions containing inulin |
EP4082511A4 (en) | 2019-12-26 | 2023-11-01 | Obschestvo s Ogranichennoi Otvetstvennostyu «WDS» | COMPOSITION FOR THE REMINERALIZATION OF DENTAL ENAMEL |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4206198A (en) * | 1979-05-16 | 1980-06-03 | Basf Wyandotte Corporation | Dentifrice |
KR900006826B1 (ko) * | 1988-03-25 | 1990-09-22 | 주식회사 럭키 | 구강 위생 증진용 치약 조성물 |
KR920005056B1 (ko) * | 1988-10-04 | 1992-06-26 | 가부시끼가이샤 야마도야 쇼 가이 | 화상 특성의 변환 처리법 |
JP2726490B2 (ja) * | 1989-05-10 | 1998-03-11 | 花王株式会社 | 口腔用組成物 |
GB2289841B (en) * | 1994-05-23 | 1998-04-15 | Janina International | Oral care products |
GB2290234B (en) * | 1994-06-07 | 1998-06-10 | Janina International | Oral care products |
US5603922A (en) * | 1995-08-08 | 1997-02-18 | Enamelon Inc. | Processes and compositions for the remineralization of teeth |
JPH09295924A (ja) * | 1996-04-30 | 1997-11-18 | Lion Corp | 歯垢の酸中和剤及び口腔用組成物 |
RU2201202C2 (ru) * | 2000-12-18 | 2003-03-27 | ОАО "Воскресенские минеральные удобрения" | Зубная паста и наполнитель для зубных паст |
US6509007B2 (en) * | 2001-03-19 | 2003-01-21 | The Procter & Gamble Company | Oral care kits and compositions |
US20030003059A1 (en) * | 2001-04-03 | 2003-01-02 | Frederic Dana | Dentifrice compositions |
JP3853785B2 (ja) * | 2002-12-27 | 2006-12-06 | 花王株式会社 | 口腔用組成物 |
RU2238716C1 (ru) * | 2003-05-29 | 2004-10-27 | Закрытое акционерное общество "Модум" | Композиция зубной пасты |
RU2239413C1 (ru) * | 2003-06-24 | 2004-11-10 | Закрытое акционерное общество "Невская косметика" | Средство для ухода за зубами |
DE10340542A1 (de) * | 2003-09-01 | 2005-03-24 | Henkel Kgaa | Mund- und Zahnpflegemittel |
US20050084551A1 (en) * | 2003-09-26 | 2005-04-21 | Jensen Claude J. | Morinda citrifolia-based oral care compositions and methods |
-
2005
- 2005-05-23 RU RU2005115513/15A patent/RU2293551C1/ru active
- 2005-11-25 ES ES05822306.6T patent/ES2541781T3/es active Active
- 2005-11-25 HU HUE05822306A patent/HUE025691T2/en unknown
- 2005-11-25 EA EA200701152A patent/EA011229B1/ru unknown
- 2005-11-25 EP EP05822306.6A patent/EP1895996B1/en active Active
- 2005-11-25 PT PT58223066T patent/PT1895996E/pt unknown
- 2005-11-25 JP JP2008513398A patent/JP5599972B2/ja active Active
- 2005-11-25 SI SI200531980T patent/SI1895996T1/sl unknown
- 2005-11-25 UA UAA200709959A patent/UA83328C2/ru unknown
- 2005-11-25 DK DK05822306.6T patent/DK1895996T3/en active
- 2005-11-25 WO PCT/RU2005/000600 patent/WO2006130040A1/en active Application Filing
- 2005-11-25 PL PL05822306T patent/PL1895996T3/pl unknown
- 2005-11-25 CN CN2005800499019A patent/CN101365418B/zh active Active
- 2005-11-25 KR KR1020077029945A patent/KR20080067284A/ko not_active Application Discontinuation
- 2005-11-25 US US11/915,334 patent/US8460643B2/en active Active
-
2007
- 2007-12-20 NO NO20076598A patent/NO337434B1/no not_active IP Right Cessation
-
2015
- 2015-06-29 HR HRP20150690TT patent/HRP20150690T1/hr unknown
- 2015-07-06 CY CY20151100585T patent/CY1116465T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO337434B1 (no) | 2016-04-11 |
KR20080067284A (ko) | 2008-07-18 |
CN101365418B (zh) | 2011-11-09 |
ES2541781T3 (es) | 2015-07-24 |
NO20076598L (no) | 2008-02-22 |
CY1116465T1 (el) | 2017-03-15 |
WO2006130040A1 (en) | 2006-12-07 |
DK1895996T3 (en) | 2015-07-06 |
HUE025691T2 (en) | 2016-04-28 |
EP1895996A4 (en) | 2013-07-17 |
EP1895996B1 (en) | 2015-04-08 |
HRP20150690T1 (hr) | 2015-09-11 |
EA011229B1 (ru) | 2009-02-27 |
EA200701152A1 (ru) | 2007-12-28 |
EP1895996A1 (en) | 2008-03-12 |
CN101365418A (zh) | 2009-02-11 |
PL1895996T3 (pl) | 2015-10-30 |
SI1895996T1 (sl) | 2015-09-30 |
UA83328C2 (ru) | 2008-06-25 |
RU2293551C1 (ru) | 2007-02-20 |
JP2008542264A (ja) | 2008-11-27 |
US20090041684A1 (en) | 2009-02-12 |
PT1895996E (pt) | 2015-08-26 |
US8460643B2 (en) | 2013-06-11 |
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