JP5589130B1 - 結晶及び該結晶を含有してなる医薬製剤 - Google Patents

結晶及び該結晶を含有してなる医薬製剤 Download PDF

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Publication number
JP5589130B1
JP5589130B1 JP2013185320A JP2013185320A JP5589130B1 JP 5589130 B1 JP5589130 B1 JP 5589130B1 JP 2013185320 A JP2013185320 A JP 2013185320A JP 2013185320 A JP2013185320 A JP 2013185320A JP 5589130 B1 JP5589130 B1 JP 5589130B1
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Prior art keywords
crystal
luliconazole
present
alcohol
ethanol
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JP2013185320A
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Japanese (ja)
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JP2015027972A (ja
Inventor
孝明 増田
誠 後藤
善之 宮田
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Pola Pharma Inc
Nihon Nohyaku Co Ltd
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Pola Pharma Inc
Nihon Nohyaku Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2013185320A 2012-09-14 2013-09-06 結晶及び該結晶を含有してなる医薬製剤 Active JP5589130B1 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2013185320A JP5589130B1 (ja) 2012-09-14 2013-09-06 結晶及び該結晶を含有してなる医薬製剤

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2012202514 2012-09-14
JP2012202514 2012-09-14
JP2013131504 2013-06-24
JP2013131504 2013-06-24
JP2013185320A JP5589130B1 (ja) 2012-09-14 2013-09-06 結晶及び該結晶を含有してなる医薬製剤

Publications (2)

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JP5589130B1 true JP5589130B1 (ja) 2014-09-10
JP2015027972A JP2015027972A (ja) 2015-02-12

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JP2013185320A Active JP5589130B1 (ja) 2012-09-14 2013-09-06 結晶及び該結晶を含有してなる医薬製剤

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Country Link
US (1) US9012484B2 (enExample)
EP (1) EP2895165B1 (enExample)
JP (1) JP5589130B1 (enExample)
CN (1) CN104284662A (enExample)
IN (1) IN2015DN02929A (enExample)
RU (1) RU2622644C2 (enExample)
WO (1) WO2014042231A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102387785B (zh) 2009-04-09 2017-08-25 宝丽制药股份有限公司 抗真菌药物组合物
CN102387786B (zh) 2009-04-09 2015-09-09 宝丽制药股份有限公司 抗真菌药物组合物
US8952044B2 (en) 2009-08-25 2015-02-10 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2011155640A1 (en) 2010-06-11 2011-12-15 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN104619704B (zh) 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
US9199977B2 (en) 2012-09-14 2015-12-01 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
JP5460797B1 (ja) 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5680161B1 (ja) * 2013-09-06 2015-03-04 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5587488B1 (ja) 2013-12-12 2014-09-10 株式会社ポーラファルマ ルリコナゾールを含有する製剤の評価方法及び指標物質
US10703744B2 (en) 2014-12-12 2020-07-07 Glenmark Life Sciences Limited Process for preparation of luliconazole
JP5951864B1 (ja) * 2015-06-05 2016-07-13 株式会社ポーラファルマ 抗ジアルジア剤
JP2017101009A (ja) 2015-12-04 2017-06-08 株式会社ポーラファルマ 抗アカントアメーバ剤及びその製造法
TR201714882A2 (tr) 2017-10-03 2019-04-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Luli̇konazolün topi̇kal farmasöti̇k kompozi̇syonlari

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09100279A (ja) * 1995-07-08 1997-04-15 Nippon Nohyaku Co Ltd 抗真菌剤、その化合物及びその製造方法並びにその使用方法
WO2009031642A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 医薬組成物
JP5453559B1 (ja) * 2012-09-14 2014-03-26 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を加工してなる医薬組成物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3081766B2 (ja) 1994-05-06 2000-08-28 東興薬品工業株式会社 角質貯留型抗真菌外用組成物
ES2137888B1 (es) * 1995-07-08 2001-01-01 Nihon Nohyaku Co Ltd Agente antifungico, compuesto para el mismo procedimiento para su produccion y metodo para su utilizacion.
JP2002114680A (ja) 2000-07-31 2002-04-16 Nippon Nohyaku Co Ltd 抗真菌剤
BRPI0621386B8 (pt) 2006-03-08 2021-07-13 Nihon Nihyaku Co Ltd composição farmacêutica para o uso externo
PL2005958T3 (pl) 2006-03-08 2013-11-29 Nihon Nohyaku Co Ltd Kompozycja farmaceutyczna do stosowania zewnętrznego
WO2007102243A1 (ja) 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物
KR20100075476A (ko) 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 항진균 조성물
HUE030028T2 (en) * 2007-09-05 2017-04-28 Pola Pharma Inc Antifungal drug
ES2468540T3 (es) 2009-02-13 2014-06-16 Topica Pharmaceuticals, Inc Formulación antif�ngica
CN102387785B (zh) 2009-04-09 2017-08-25 宝丽制药股份有限公司 抗真菌药物组合物
CN102387786B (zh) 2009-04-09 2015-09-09 宝丽制药股份有限公司 抗真菌药物组合物
US8952044B2 (en) 2009-08-25 2015-02-10 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2011155640A1 (en) 2010-06-11 2011-12-15 Pola Pharma Inc. Antimycotic pharmaceutical composition
US8728210B2 (en) 2011-07-07 2014-05-20 Hsueh Yuan Lee Exhaust gas treatment apparatus and method
CN103012385B (zh) * 2012-02-17 2015-07-08 山东威智医药工业有限公司 卢立康唑的晶型及其制备方法
CN104619320A (zh) 2012-09-14 2015-05-13 宝丽制药股份有限公司 含有卢立康唑的药物组合物
JP5460797B1 (ja) 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
CN104619704B (zh) 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09100279A (ja) * 1995-07-08 1997-04-15 Nippon Nohyaku Co Ltd 抗真菌剤、その化合物及びその製造方法並びにその使用方法
WO2009031642A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 医薬組成物
JP5453559B1 (ja) * 2012-09-14 2014-03-26 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を加工してなる医薬組成物

Also Published As

Publication number Publication date
RU2622644C2 (ru) 2017-06-19
RU2015113638A (ru) 2016-11-10
US20140080882A1 (en) 2014-03-20
JP2015027972A (ja) 2015-02-12
EP2895165B1 (en) 2016-12-14
IN2015DN02929A (enExample) 2015-09-18
EP2895165A1 (en) 2015-07-22
WO2014042231A1 (en) 2014-03-20
CN104284662A (zh) 2015-01-14
US9012484B2 (en) 2015-04-21

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