JP5558348B2 - シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 - Google Patents
シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 Download PDFInfo
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- JP5558348B2 JP5558348B2 JP2010515728A JP2010515728A JP5558348B2 JP 5558348 B2 JP5558348 B2 JP 5558348B2 JP 2010515728 A JP2010515728 A JP 2010515728A JP 2010515728 A JP2010515728 A JP 2010515728A JP 5558348 B2 JP5558348 B2 JP 5558348B2
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- fatty liver
- liver
- cilostazol
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- therapeutic agent
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
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- Obesity (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010515728A JP5558348B2 (ja) | 2007-07-11 | 2008-07-09 | シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007181760 | 2007-07-11 | ||
| JP2007181760 | 2007-07-11 | ||
| PCT/JP2008/062771 WO2009008539A1 (en) | 2007-07-11 | 2008-07-09 | Carbostyril derivatives including cilostazol for treating fatty liver |
| JP2010515728A JP5558348B2 (ja) | 2007-07-11 | 2008-07-09 | シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014115759A Division JP2014185161A (ja) | 2007-07-11 | 2014-06-04 | シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010533166A JP2010533166A (ja) | 2010-10-21 |
| JP2010533166A5 JP2010533166A5 (enExample) | 2011-05-19 |
| JP5558348B2 true JP5558348B2 (ja) | 2014-07-23 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515728A Expired - Fee Related JP5558348B2 (ja) | 2007-07-11 | 2008-07-09 | シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 |
| JP2014115759A Withdrawn JP2014185161A (ja) | 2007-07-11 | 2014-06-04 | シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014115759A Withdrawn JP2014185161A (ja) | 2007-07-11 | 2014-06-04 | シロスタゾールを含むカルボスチリル誘導体の脂肪肝治療剤 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8642618B2 (enExample) |
| EP (1) | EP2162134A1 (enExample) |
| JP (2) | JP5558348B2 (enExample) |
| KR (2) | KR20100046188A (enExample) |
| CN (1) | CN101778630A (enExample) |
| AR (1) | AR067446A1 (enExample) |
| CA (1) | CA2691632A1 (enExample) |
| TW (1) | TW200908973A (enExample) |
| WO (1) | WO2009008539A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101094934B1 (ko) * | 2010-10-22 | 2011-12-15 | 영남대학교 산학협력단 | 실로스타졸을 유효성분으로 함유하는 알코올성 간질환 치료 또는 예방용 약학조성물 |
| EP3263705A1 (en) * | 2016-06-28 | 2018-01-03 | DKFZ Deutsches Krebsforschungszentrum | Treatments of non-alcoholic steatohepatitis (nash) |
| TWI677348B (zh) | 2016-12-15 | 2019-11-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種改善心臟病變的方法 |
| TWI750189B (zh) | 2016-12-15 | 2021-12-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種治療冠狀動脈粥樣硬化及其併發症的方法 |
| JP7168990B2 (ja) | 2016-12-15 | 2022-11-10 | タレンゲン インターナショナル リミテッド | 肥満症を予防および治療するための方法および薬物 |
| CN117255694A (zh) * | 2021-05-11 | 2023-12-19 | 雷杰纳荣制药公司 | 用磷酸二酯酶3b(pde3b)抑制剂治疗肝病的方法 |
| EP4395888A1 (en) * | 2021-08-31 | 2024-07-10 | Regeneron Pharmaceuticals, Inc. | Treatment of liver diseases with camp responsive element binding protein 3 like 3 (creb3l3) inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3944257B2 (ja) * | 1995-12-07 | 2007-07-11 | 大塚製薬株式会社 | 肝実質細胞増殖因子産生増加剤 |
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2008
- 2008-07-03 AR ARP080102879A patent/AR067446A1/es unknown
- 2008-07-09 JP JP2010515728A patent/JP5558348B2/ja not_active Expired - Fee Related
- 2008-07-09 KR KR1020107002982A patent/KR20100046188A/ko not_active Abandoned
- 2008-07-09 KR KR20157007589A patent/KR20150038739A/ko not_active Ceased
- 2008-07-09 CN CN200880024072A patent/CN101778630A/zh active Pending
- 2008-07-09 EP EP08791177A patent/EP2162134A1/en not_active Withdrawn
- 2008-07-09 US US12/667,875 patent/US8642618B2/en not_active Expired - Fee Related
- 2008-07-09 CA CA002691632A patent/CA2691632A1/en not_active Abandoned
- 2008-07-09 WO PCT/JP2008/062771 patent/WO2009008539A1/en not_active Ceased
- 2008-07-10 TW TW097126022A patent/TW200908973A/zh unknown
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2013
- 2013-12-24 US US14/140,179 patent/US20140121241A1/en not_active Abandoned
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2014
- 2014-06-04 JP JP2014115759A patent/JP2014185161A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150038739A (ko) | 2015-04-08 |
| KR20100046188A (ko) | 2010-05-06 |
| US20110039887A1 (en) | 2011-02-17 |
| WO2009008539A1 (en) | 2009-01-15 |
| US8642618B2 (en) | 2014-02-04 |
| EP2162134A1 (en) | 2010-03-17 |
| US20140121241A1 (en) | 2014-05-01 |
| CN101778630A (zh) | 2010-07-14 |
| CA2691632A1 (en) | 2009-01-15 |
| AR067446A1 (es) | 2009-10-14 |
| TW200908973A (en) | 2009-03-01 |
| JP2014185161A (ja) | 2014-10-02 |
| JP2010533166A (ja) | 2010-10-21 |
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