JP5524082B2 - ヒスタミン−３（ｈ３）受容体リガンドとしての置換スピロ環状ピペリジン誘導体 - Google Patents
ヒスタミン−３（ｈ３）受容体リガンドとしての置換スピロ環状ピペリジン誘導体 Download PDFInfo
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- JP5524082B2 JP5524082B2 JP2010545098A JP2010545098A JP5524082B2 JP 5524082 B2 JP5524082 B2 JP 5524082B2 JP 2010545098 A JP2010545098 A JP 2010545098A JP 2010545098 A JP2010545098 A JP 2010545098A JP 5524082 B2 JP5524082 B2 JP 5524082B2
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Classifications
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Landscapes
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- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Urology & Nephrology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6290908P | 2008-01-30 | 2008-01-30 | |
| US61/062,909 | 2008-01-30 | ||
| PCT/US2009/032195 WO2009097309A1 (en) | 2008-01-30 | 2009-01-28 | Substituted spirocyclic piperidine derivatives as histamine-3 (h3) receptor ligands |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011510992A JP2011510992A (ja) | 2011-04-07 |
| JP2011510992A5 JP2011510992A5 (https=) | 2013-04-04 |
| JP5524082B2 true JP5524082B2 (ja) | 2014-06-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545098A Expired - Fee Related JP5524082B2 (ja) | 2008-01-30 | 2009-01-28 | ヒスタミン−３（ｈ３）受容体リガンドとしての置換スピロ環状ピペリジン誘導体 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8524713B2 (https=) |
| EP (1) | EP2257553B1 (https=) |
| JP (1) | JP5524082B2 (https=) |
| KR (1) | KR20100105789A (https=) |
| CN (1) | CN101932585B (https=) |
| AT (1) | ATE522538T1 (https=) |
| AU (1) | AU2009209235B2 (https=) |
| BR (1) | BRPI0905849A2 (https=) |
| CA (1) | CA2712888A1 (https=) |
| EA (1) | EA018537B1 (https=) |
| ES (1) | ES2370378T3 (https=) |
| IL (1) | IL206914A (https=) |
| MX (1) | MX2010008382A (https=) |
| MY (1) | MY150062A (https=) |
| NZ (1) | NZ587034A (https=) |
| UA (1) | UA100877C2 (https=) |
| WO (1) | WO2009097309A1 (https=) |
| ZA (1) | ZA201005136B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20130044T1 (hr) | 2006-07-25 | 2013-02-28 | Cephalon, Inc. | Derivati piridizinona |
| EP2752406A1 (en) | 2008-01-30 | 2014-07-09 | Cephalon, Inc. | Substituted pyridazine derivatives which have histamine H3 antagonist activity |
| WO2009142732A2 (en) * | 2008-05-20 | 2009-11-26 | Cephalon, Inc. | Substituted pyridazinone derivatives as histamine-3 (h3) receptor ligands |
| CN102099036B (zh) | 2008-06-03 | 2015-05-27 | 英特芒尼公司 | 用于治疗炎性疾患和纤维化疾患的化合物和方法 |
| TWI522361B (zh) | 2010-07-09 | 2016-02-21 | 艾伯維公司 | 作為s1p調節劑的稠合雜環衍生物 |
| TW201643169A (zh) | 2010-07-09 | 2016-12-16 | 艾伯維股份有限公司 | 作為s1p調節劑的螺-哌啶衍生物 |
| TW201206893A (en) | 2010-07-09 | 2012-02-16 | Abbott Healthcare Products Bv | Bisaryl (thio) morpholine derivatives as S1P modulators |
| WO2012077655A1 (ja) * | 2010-12-07 | 2012-06-14 | 塩野義製薬株式会社 | Ｇｐｒ１１９アゴニスト活性を有するスピロ誘導体 |
| ES2547916T3 (es) | 2011-02-18 | 2015-10-09 | Novartis Pharma Ag | Terapia de combinación de inhibidores de mTOR/JAK |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| MX382781B (es) | 2014-04-02 | 2025-03-13 | Intermune Inc | Piridinonas anti-fibroticas. |
| JP6643764B2 (ja) * | 2016-02-05 | 2020-02-12 | 国立大学法人岐阜大学 | 抗がん剤 |
| EP3684364A4 (en) | 2017-09-18 | 2021-06-02 | Goldfinch Bio, Inc. | PYRIDAZINONE AND METHOD OF USE THEREOF |
| US11535632B2 (en) | 2019-10-31 | 2022-12-27 | ESCAPE Bio, Inc. | Solid forms of an S1P-receptor modulator |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0313762D0 (en) * | 2003-06-13 | 2003-07-23 | Biofocus Plc | Compound libraries |
| NZ546834A (en) * | 2003-10-01 | 2010-03-26 | Adolor Corp | Spirocyclic heterocyclic derivatives and methods of their use |
| SE0403160D0 (sv) * | 2004-12-23 | 2004-12-23 | Biovitrum Ab | New compounds |
| ES2381205T3 (es) * | 2005-11-10 | 2012-05-24 | Msd K.K. | Derivado espiro aza-sustituido |
| WO2007063385A2 (en) * | 2005-12-01 | 2007-06-07 | Pfizer Products Inc. | Spirocyclic amine histamine-3 receptor antagonists |
| WO2007088462A1 (en) * | 2006-02-01 | 2007-08-09 | Pfizer Products Inc. | Spirochromane antagonists of the h-3 receptor |
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2009
- 2009-01-28 UA UAA201010456A patent/UA100877C2/ru unknown
- 2009-01-28 ES ES09706445T patent/ES2370378T3/es active Active
- 2009-01-28 AT AT09706445T patent/ATE522538T1/de not_active IP Right Cessation
- 2009-01-28 BR BRPI0905849-4A patent/BRPI0905849A2/pt not_active IP Right Cessation
- 2009-01-28 KR KR1020107019040A patent/KR20100105789A/ko not_active Ceased
- 2009-01-28 AU AU2009209235A patent/AU2009209235B2/en not_active Ceased
- 2009-01-28 MY MYPI2010003298A patent/MY150062A/en unknown
- 2009-01-28 EP EP09706445A patent/EP2257553B1/en not_active Not-in-force
- 2009-01-28 CN CN2009801037142A patent/CN101932585B/zh not_active Expired - Fee Related
- 2009-01-28 JP JP2010545098A patent/JP5524082B2/ja not_active Expired - Fee Related
- 2009-01-28 NZ NZ587034A patent/NZ587034A/en not_active IP Right Cessation
- 2009-01-28 EA EA201070903A patent/EA018537B1/ru not_active IP Right Cessation
- 2009-01-28 MX MX2010008382A patent/MX2010008382A/es active IP Right Grant
- 2009-01-28 CA CA2712888A patent/CA2712888A1/en not_active Abandoned
- 2009-01-28 WO PCT/US2009/032195 patent/WO2009097309A1/en not_active Ceased
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2010
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- 2010-07-19 ZA ZA2010/05136A patent/ZA201005136B/en unknown
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2013
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Also Published As
| Publication number | Publication date |
|---|---|
| US20100298332A1 (en) | 2010-11-25 |
| EP2257553B1 (en) | 2011-08-31 |
| MY150062A (en) | 2013-11-29 |
| CN101932585B (zh) | 2013-07-10 |
| IL206914A0 (en) | 2010-12-30 |
| ZA201005136B (en) | 2013-12-23 |
| HK1151526A1 (en) | 2012-02-03 |
| WO2009097309A1 (en) | 2009-08-06 |
| AU2009209235A1 (en) | 2009-08-06 |
| ES2370378T3 (es) | 2011-12-14 |
| IL206914A (en) | 2013-03-24 |
| EA201070903A1 (ru) | 2011-02-28 |
| MX2010008382A (es) | 2010-11-25 |
| US8524713B2 (en) | 2013-09-03 |
| ATE522538T1 (de) | 2011-09-15 |
| UA100877C2 (ru) | 2013-02-11 |
| BRPI0905849A2 (pt) | 2015-06-30 |
| KR20100105789A (ko) | 2010-09-29 |
| NZ587034A (en) | 2011-12-22 |
| AU2009209235B2 (en) | 2013-07-18 |
| EP2257553A1 (en) | 2010-12-08 |
| US20130310389A1 (en) | 2013-11-21 |
| EA018537B1 (ru) | 2013-08-30 |
| CN101932585A (zh) | 2010-12-29 |
| CA2712888A1 (en) | 2009-08-06 |
| JP2011510992A (ja) | 2011-04-07 |
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