JP5514553B2 - ホログラフィックにトラップされた3次元構造のホログラフィック顕微鏡法 - Google Patents
ホログラフィックにトラップされた3次元構造のホログラフィック顕微鏡法 Download PDFInfo
- Publication number
- JP5514553B2 JP5514553B2 JP2009547444A JP2009547444A JP5514553B2 JP 5514553 B2 JP5514553 B2 JP 5514553B2 JP 2009547444 A JP2009547444 A JP 2009547444A JP 2009547444 A JP2009547444 A JP 2009547444A JP 5514553 B2 JP5514553 B2 JP 5514553B2
- Authority
- JP
- Japan
- Prior art keywords
- light
- image
- trapped
- laser
- trapping
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000386 microscopy Methods 0.000 title claims description 12
- 230000003287 optical effect Effects 0.000 claims description 28
- 238000000034 method Methods 0.000 claims description 20
- 238000003384 imaging method Methods 0.000 claims description 19
- 238000005286 illumination Methods 0.000 claims description 12
- 230000001427 coherent effect Effects 0.000 claims description 5
- 238000004364 calculation method Methods 0.000 claims description 3
- CPBQJMYROZQQJC-UHFFFAOYSA-N helium neon Chemical compound [He].[Ne] CPBQJMYROZQQJC-UHFFFAOYSA-N 0.000 claims description 2
- 230000002452 interceptive effect Effects 0.000 claims description 2
- 238000000651 laser trapping Methods 0.000 claims description 2
- 238000011144 upstream manufacturing Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 description 13
- 239000000523 sample Substances 0.000 description 10
- 238000010586 diagram Methods 0.000 description 8
- 238000004458 analytical method Methods 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 239000010419 fine particle Substances 0.000 description 3
- 238000012576 optical tweezer Methods 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 238000000149 argon plasma sintering Methods 0.000 description 2
- 238000009647 digital holographic microscopy Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000000339 bright-field microscopy Methods 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000004624 confocal microscopy Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 238000005381 potential energy Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 210000001747 pupil Anatomy 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/0005—Adaptation of holography to specific applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
- G01B9/00—Measuring instruments characterised by the use of optical techniques
- G01B9/02—Interferometers
- G01B9/021—Interferometers using holographic techniques
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/32—Micromanipulators structurally combined with microscopes
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/04—Processes or apparatus for producing holograms
- G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/0004—Microscopes specially adapted for specific applications
- G02B21/0088—Inverse microscopes
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/04—Processes or apparatus for producing holograms
- G03H1/08—Synthesising holograms, i.e. holograms synthesized from objects or objects from holograms
- G03H1/0866—Digital holographic imaging, i.e. synthesizing holobjects from holograms
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/22—Processes or apparatus for obtaining an optical image from holograms
- G03H1/2294—Addressing the hologram to an active spatial light modulator
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/0005—Adaptation of holography to specific applications
- G03H2001/0033—Adaptation of holography to specific applications in hologrammetry for measuring or analysing
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/0005—Adaptation of holography to specific applications
- G03H2001/0077—Adaptation of holography to specific applications for optical manipulation, e.g. holographic optical tweezers [HOT]
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
- G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
- G03H1/04—Processes or apparatus for producing holograms
- G03H1/0443—Digital holography, i.e. recording holograms with digital recording means
- G03H2001/0447—In-line recording arrangement
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S359/00—Optical: systems and elements
- Y10S359/902—Holographic interferometer
Landscapes
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Computing Systems (AREA)
- Theoretical Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Optics & Photonics (AREA)
- Holo Graphy (AREA)
- Microscoopes, Condenser (AREA)
Description
本願は2007年1月26日に出願された米国特許出願第60/897,784号の米国特許法(35 U.S.C.)第119条(e)項に基づく利益を主張するものである。同特許出願はこの参照によりその内容全体が本願明細書に含まれるものとする。
本発明は、コンピュータで設定されたホログラムによって生成される光トラップを利用して試料を立体的に配置し、顕微鏡光学系を適用して3次元で該試料を検査・分析するためのホログラフィック光トラッピングシステムに関する。特に、ホログラフィックビデオ顕微鏡システムは3D微細構造のリアルタイムの分解体積画像を使用して試料集合体の分析と検査を実行する。
Claims (18)
- 光学顕微鏡を提供するステップと、
前記光学顕微鏡に入力される光学照明のための付随するイメージング波長を有する、イメージングレーザからの第1のレーザ光線を生成するステップと、
複数の光トラップを生成するステップであって、改良点として、光トラップされた構造と互いに作用する入射照明光として前記第1のレーザ光線を用い、前記光トラップされた構造により前記第1のレーザ光線から散乱された光が前記入射照明光の残りと干渉し、ヘテロダイン干渉パタンを形成し、トラッピングレーザからの第2のレーザ光線を用いて前記複数の光トラップを生成し、所望の光トラッピングパタンを符号化する位相限定ホログラムを有する付随するトラッピング波長を持つトラッピング用レーザ光線の波面を用いることを含む、ステップと、
前記光学顕微鏡の対物レンズを提供するステップであって、当該対物レンズが、前記複数の光トラップを投影するとともに前記トラップされた構造のインラインホログラフィック像を収集する、ステップと、
前記トラップされた構造の像をカメラに提供するとともに前記レイリー・ゾンマーフェルト形式を前記トラップされた構造の3Dホログラフィック顕微鏡法に用いてそれらの画像を解析するステップと
を含む、レイリー・ゾンマーフェルト形式を用いて光トラップされた構造を解析する3D(3次元)ホログラフィック顕微鏡法を実行する方法。 - 前記対物レンズと前記カメラとの間に、前記トラッピング用レーザ光線のトラッピング波長に合わせたダイクロイックミラーを間置するステップを更に含む請求項1に記載の方法。
- 前記画像は前記トラップされた構造を焦点面から並進移動させることによって最小化可能なゴーストを含む請求項1に記載の方法。
- 前記イメージング用レーザ光線は平行光線出力を有するヘリウムネオンレーザによって提供される請求項1に記載の方法。
- 前記光学顕微鏡は焦点面を含み、当該方法は、トラップされた構造の3次元ホログラフィック顕微鏡法を実行する機械的な動きを一切含まない請求項1に記載の方法。
- 前記カメラにおいて形成された画像から参照画像を差し引くステップを更に含み、それにより、トラップされた構造が一切存在しないときの変動するバックグランド照明が除去される請求項1に記載の方法。
- 前記トラップされた構造の画像は3次元複素数値ライトフィールドを再構成するための2次元実数値画像を含む請求項1に記載の方法。
- 前記レイリー・ゾンマーフェルト形式は前記光学顕微鏡の光軸に沿ったトラップされた構造の伝搬を解析することを含む請求項1に記載の方法。
- 前記ライトフィールドv(r、z)は前記画像の単一ホログラフィックスナップショットから再構成される請求項10に記載の方法。
- 前記トラップされた構造の動きを追跡するステップを更に含む請求項11に記載の方法。
- 前記トラップされた構造は遮られた複数のオブジェクトを含み、その3次元画像が再構成され、前記複数のオブジェクトは再構成されたライトフィールドの中で全て分解される請求項11に記載の方法。
- 前記光学顕微鏡の複数の焦点面から画像データを取得するステップと、前記トラップされた構造を複数のアングルから照明するステップの少なくとも1つのステップを更に含み、それにより、前記トラップされた構造の画像の精度を高めるようにした請求項1に記載の方法。
- 光学顕微鏡と、
トラッピング用レーザ光線を生み出すための第1のレーザ源と、
前記トラッピング用レーザ光線にインプリントするための位相限定ホログラムを提供するための空間光変調器と、
イメージング用レーザ光線を生み出すための第2のレーザ源とを備え、改良点として、前記イメージング用レーザ光線に対して、所望の光トラッピングパタンを符号化する位相限定ホログラムを有するトラッピング用レーザ光線を形成するために異なるレーザ光線を用い、前記第2のレーザ源は光トラップされた構造と互いに作用する入射照明光を提供し、前記光トラップされた構造により前記イメージング用レーザ光線から分散された光が前記入射照明光の残りと干渉しヘテロダイン干渉パタンを生成するものであり、
さらに
倒立型光学顕微鏡を構成する、前記光学顕微鏡に付随する対物レンズと、
前記トラップされた構造のイメージングから生じるレーザ光を検出し、画像データを出力するCCDカメラと、
前記レイリー・ゾンマーフェルト形式を適用して前記画像データを解析するコンピュータソフトウェアを実行して前記画像データを解析するためのコンピュータと
を備える、レイリー・ゾンマーフェルト形式を用いて光トラップされた構造を解析する3D(3次元)ホログラフィック顕微鏡法を実行するシステム。 - 前記レーザ源はコヒーレント光の平行光線を生み出すレーザを含む請求項15に記載のシステム。
- 前記対物レンズと前記CCDカメラとの間に間置されたダイクロイックミラーを更に備える請求項15に記載のシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89778407P | 2007-01-26 | 2007-01-26 | |
US60/897,784 | 2007-01-26 | ||
PCT/US2008/052098 WO2008092107A1 (en) | 2007-01-26 | 2008-01-25 | Holographic microscope system and method for optical trapping and inspection of materials |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2010517102A JP2010517102A (ja) | 2010-05-20 |
JP2010517102A5 JP2010517102A5 (ja) | 2013-07-18 |
JP5514553B2 true JP5514553B2 (ja) | 2014-06-04 |
Family
ID=39410014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009547444A Expired - Fee Related JP5514553B2 (ja) | 2007-01-26 | 2008-01-25 | ホログラフィックにトラップされた3次元構造のホログラフィック顕微鏡法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US7839551B2 (ja) |
EP (2) | EP2106611B1 (ja) |
JP (1) | JP5514553B2 (ja) |
CN (2) | CN101632134A (ja) |
WO (1) | WO2008092107A1 (ja) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8149416B2 (en) * | 2005-10-17 | 2012-04-03 | Arryx, Inc. | Apparatus and method for dynamic cellular probing and diagnostics using holographic optical forcing array |
US8121361B2 (en) | 2006-05-19 | 2012-02-21 | The Queen's Medical Center | Motion tracking system for real time adaptive imaging and spectroscopy |
WO2008127410A2 (en) * | 2006-11-07 | 2008-10-23 | New York University | Holographic microfabrication and characterization system for soft matter and biological systems |
DK3079023T3 (da) | 2007-10-30 | 2019-12-09 | Univ New York | Sporing og karakteriseing af partikler med holografisk videomikroskop |
US8049814B2 (en) | 2008-03-27 | 2011-11-01 | The Rockefeller University | Holographic microscope |
US9846313B2 (en) * | 2008-09-25 | 2017-12-19 | The Trustees Of Columbia University In The City Of New York | Devices, apparatus and method for providing photostimulation and imaging of structures |
US9316578B2 (en) | 2008-10-30 | 2016-04-19 | New York University | Automated real-time particle characterization and three-dimensional velocimetry with holographic video microscopy |
US8451450B2 (en) * | 2009-09-14 | 2013-05-28 | Bio-Rad Laboratories, Inc. | Near real time optical phase conjugation |
JP5554965B2 (ja) * | 2009-11-06 | 2014-07-23 | オリンパス株式会社 | 位相変調型空間光変調器を用いたレーザ顕微鏡 |
US8711211B2 (en) * | 2010-06-14 | 2014-04-29 | Howard Hughes Medical Institute | Bessel beam plane illumination microscope |
US10051240B2 (en) * | 2010-06-14 | 2018-08-14 | Howard Hughes Medical Institute | Structured plane illumination microscopy |
EP2592459B8 (en) * | 2010-07-07 | 2017-12-13 | University of Hyogo | Holographic microscope and method for processing microscopic subject hologram image |
CN102147539B (zh) * | 2011-03-30 | 2012-06-27 | 中山大学 | 一种基于纯相位型液晶空间光调制器的一维周期结构光场产生方法 |
US9606209B2 (en) | 2011-08-26 | 2017-03-28 | Kineticor, Inc. | Methods, systems, and devices for intra-scan motion correction |
US9147102B2 (en) * | 2012-01-02 | 2015-09-29 | Camtek Ltd. | Method and system for measuring bumps based on phase and amplitude information |
RU2496165C1 (ru) * | 2012-02-21 | 2013-10-20 | Объединенный Институт Ядерных Исследований | Криогенный дозатор шариков для холодного замедлителя нейтронов |
US10327708B2 (en) | 2013-01-24 | 2019-06-25 | Kineticor, Inc. | Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan |
US9717461B2 (en) | 2013-01-24 | 2017-08-01 | Kineticor, Inc. | Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan |
US9305365B2 (en) | 2013-01-24 | 2016-04-05 | Kineticor, Inc. | Systems, devices, and methods for tracking moving targets |
WO2014120734A1 (en) | 2013-02-01 | 2014-08-07 | Kineticor, Inc. | Motion tracking system for real time adaptive motion compensation in biomedical imaging |
US20140235948A1 (en) * | 2013-02-19 | 2014-08-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method for single-fiber microscopy using intensity-pattern sampling and optimization-based reconstruction |
WO2014136784A1 (ja) | 2013-03-06 | 2014-09-12 | 浜松ホトニクス株式会社 | 蛍光受光装置および蛍光受光方法 |
EP3105638B1 (en) | 2014-02-12 | 2020-07-22 | New York University | Fast feature identification for holographic tracking and characterization of colloidal particles |
US10004462B2 (en) | 2014-03-24 | 2018-06-26 | Kineticor, Inc. | Systems, methods, and devices for removing prospective motion correction from medical imaging scans |
US10156522B2 (en) * | 2014-04-17 | 2018-12-18 | The Regents Of The University Of California | Parallel acquisition of spectral signals from a 2-D laser beam array |
CN104001692B (zh) * | 2014-05-16 | 2016-03-02 | 中南大学 | 一种基于全息光镊原理清洗材料的装置及方法 |
CN104090364B (zh) * | 2014-05-16 | 2016-03-02 | 北京理工大学 | 一种远场光场全矢量计算的方法 |
EP3188660A4 (en) | 2014-07-23 | 2018-05-16 | Kineticor, Inc. | Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan |
WO2016077472A1 (en) | 2014-11-12 | 2016-05-19 | New York University | Colloidal fingerprints for soft materials using total holographic characterization |
KR101703543B1 (ko) * | 2015-04-23 | 2017-02-07 | 연세대학교 산학협력단 | 디지털 홀로그래피 방법을 결합한 다중모드 sted 현미경시스템 |
US10989661B2 (en) | 2015-05-01 | 2021-04-27 | The Board Of Regents Of The University Of Texas System | Uniform and scalable light-sheets generated by extended focusing |
US9943247B2 (en) | 2015-07-28 | 2018-04-17 | The University Of Hawai'i | Systems, devices, and methods for detecting false movements for motion correction during a medical imaging scan |
KR102579248B1 (ko) | 2015-09-18 | 2023-09-15 | 뉴욕 유니버시티 | 정밀 슬러리 내 대형 불순물 입자의 홀로그래픽 검출 및 특성화 |
US10716515B2 (en) | 2015-11-23 | 2020-07-21 | Kineticor, Inc. | Systems, devices, and methods for tracking and compensating for patient motion during a medical imaging scan |
US11385157B2 (en) | 2016-02-08 | 2022-07-12 | New York University | Holographic characterization of protein aggregates |
US10876970B2 (en) | 2016-04-12 | 2020-12-29 | The Board Of Regents Of The University Of Texas System | Light-sheet microscope with parallelized 3D image acquisition |
US10670677B2 (en) | 2016-04-22 | 2020-06-02 | New York University | Multi-slice acceleration for magnetic resonance fingerprinting |
CN106908946B (zh) * | 2016-05-05 | 2019-03-22 | 中国计量大学 | 一种简化的双光束光镊系统 |
KR101783404B1 (ko) * | 2016-10-07 | 2017-10-10 | 한국과학기술원 | 홀로그램을 통한 광포획 원자 수송 장치 및 방법 |
NL2019891B1 (en) | 2017-11-10 | 2019-05-17 | Lumicks Tech B V | Label-free microscopy |
US10607064B2 (en) * | 2018-05-21 | 2020-03-31 | Himax Technologies Limited | Optical projection system and optical projection method |
CN115903205A (zh) | 2018-11-02 | 2023-04-04 | 豪洛捷公司 | 用于检视整个样本图像的系统 |
US11543338B2 (en) | 2019-10-25 | 2023-01-03 | New York University | Holographic characterization of irregular particles |
US11948302B2 (en) | 2020-03-09 | 2024-04-02 | New York University | Automated holographic video microscopy assay |
CN112067532B (zh) * | 2020-04-29 | 2021-12-28 | 天津农学院 | 测量微粒三维位移光轴向位置的复合式数字全息显微方法 |
US20210397129A1 (en) * | 2020-06-19 | 2021-12-23 | New York University | System and method for real-time in-situ holographic microscopy |
CN111816343B (zh) * | 2020-07-01 | 2022-07-19 | 浙江大学 | 一种利用正弦相位调制实现多位置光阱的方法和装置 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6055106A (en) * | 1998-02-03 | 2000-04-25 | Arch Development Corporation | Apparatus for applying optical gradient forces |
US7133203B2 (en) * | 1998-02-03 | 2006-11-07 | Arch Development Corporation | Apparatus for applying optical gradient forces |
TW531661B (en) * | 2000-10-06 | 2003-05-11 | Arch Dev Corp | Method of controllably filling an array of small particles, method of controllably manipulating an array of optical traps, and apparatus for controllably manipulating an array of optical traps |
CA2724743C (fr) * | 2001-06-29 | 2014-11-25 | Universite Libre De Bruxelles | Procede et dispositif destines a l'obtention par microscopie d'images en trois dimensions d'un echantillon |
US20030021016A1 (en) * | 2001-07-27 | 2003-01-30 | Grier David G. | Parallel scanned laser confocal microscope |
US6943924B2 (en) * | 2001-12-04 | 2005-09-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Apparatus and method for digital holographic imaging |
US6863406B2 (en) * | 2002-08-01 | 2005-03-08 | The University Of Chicago | Apparatus and method for fabricating, sorting, and integrating materials with holographic optical traps |
JP2004325944A (ja) * | 2003-04-25 | 2004-11-18 | Canon Inc | 微小物体処理装置 |
US7233423B2 (en) * | 2003-05-16 | 2007-06-19 | University Of Chicago | Optical fractionation methods and apparatus |
US20060153037A1 (en) | 2003-07-07 | 2006-07-13 | Pioneer Corporation | Information recording medium, recording apparatus and recording method for information recording medium, reproducing apparatus and reproducing method for information recording medium, computer program for controlling recording or reproduction, and data structure including control signal |
CN1886684A (zh) * | 2003-10-28 | 2006-12-27 | 阿而利克斯公司 | 使用全息光学俘获操纵和处理材料的系统和方法 |
JP2005337730A (ja) * | 2004-05-24 | 2005-12-08 | Nara Institute Of Science & Technology | 測定システム |
WO2006058187A2 (en) * | 2004-11-23 | 2006-06-01 | Robert Eric Betzig | Optical lattice microscopy |
US7473890B2 (en) * | 2004-11-23 | 2009-01-06 | New York University | Manipulation of objects in potential energy landscapes |
WO2007008921A2 (en) * | 2005-07-12 | 2007-01-18 | Arryx, Inc. | Method and apparatus for forming multi-dimensional colloidal structures using holographic optical tweezers |
-
2008
- 2008-01-25 JP JP2009547444A patent/JP5514553B2/ja not_active Expired - Fee Related
- 2008-01-25 US US12/020,376 patent/US7839551B2/en active Active
- 2008-01-25 WO PCT/US2008/052098 patent/WO2008092107A1/en active Application Filing
- 2008-01-25 EP EP08728321A patent/EP2106611B1/en active Active
- 2008-01-25 CN CN200880003125.2A patent/CN101632134A/zh active Pending
- 2008-01-25 EP EP12169084A patent/EP2492921A1/en not_active Withdrawn
- 2008-01-25 CN CN2012103519707A patent/CN102866494A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2010517102A (ja) | 2010-05-20 |
US20090027747A1 (en) | 2009-01-29 |
WO2008092107B1 (en) | 2008-11-06 |
US7839551B2 (en) | 2010-11-23 |
CN101632134A (zh) | 2010-01-20 |
EP2106611A1 (en) | 2009-10-07 |
EP2492921A1 (en) | 2012-08-29 |
EP2106611B1 (en) | 2013-01-23 |
CN102866494A (zh) | 2013-01-09 |
WO2008092107A1 (en) | 2008-07-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5514553B2 (ja) | ホログラフィックにトラップされた3次元構造のホログラフィック顕微鏡法 | |
US8331019B2 (en) | Holographic microscopy of holographically trapped three-dimensional nanorod structures | |
TWI655522B (zh) | 結構光照明數位全像之方法與裝置 | |
JP4772961B2 (ja) | ディジタル・ホログラムを数値的に再構成することにより、振幅コントラスト画像と定量的位相コントラスト画像を同時に形成する方法 | |
US6943924B2 (en) | Apparatus and method for digital holographic imaging | |
US7948632B2 (en) | Method and apparatus for analysis of a sample of cells | |
US10156829B2 (en) | Holographic microscope and data processing method for high-resolution hologram image | |
JP7170342B2 (ja) | ホログラフィック3次元マルチスポット光刺激装置及び方法 | |
US20130057935A1 (en) | Apparatus for the exact reconstruction of the object wave in off-axis digital holography | |
TWI797377B (zh) | 表面形狀量測裝置以及表面形狀量測方法 | |
CN114324245B (zh) | 基于部分相干结构光照明的定量相位显微装置和方法 | |
Stockton et al. | Tomographic single pixel spatial frequency projection imaging | |
JP2012145361A (ja) | デジタルホログラフィ装置 | |
RU2319948C2 (ru) | Способ получения изображения повышенной разрешающей способности | |
EP3855252B1 (en) | Method and apparatus for the phase retrieval and volumetric imaging reconstruction | |
WO2022032074A1 (en) | Simple in-line digital holography system for measuring 3d cell shape | |
JP7432227B2 (ja) | 位相イメージング装置、位相イメージング方法 | |
Thompson | Optical Imaging of Particles | |
Depeursinge et al. | Application of Digital Holographic Micros-copy in Biomedicine | |
WO2023223322A1 (en) | Single viewpoint tomography system using point spread functions of tilted pseudo-nondiffracting beams | |
CN117197386A (zh) | 一种单击无透镜光学衍射层析成像方法及系统 | |
Wichitwong | Application of digital holography for metrology of inclusions in a droplet | |
Almoro et al. | THE EUROPEAN OPTI CAL SOCI ETY | |
Tu et al. | Super-resolution imaging in a close-packed synthetic aperture digital holographic microscopy | |
Ferraro et al. | Imaging 3-D Objects by Extending the Depth of Focus in Digital Holography |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20110124 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20110124 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20120822 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20121130 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130227 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20130306 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130401 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20130408 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20130430 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20130509 |
|
A524 | Written submission of copy of amendment under article 19 pct |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20130528 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20131011 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20140114 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20140121 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140207 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20140304 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20140331 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5514553 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |