JP5449134B2 - 未熟児合併症の治療及び/又は予防の方法と製品 - Google Patents

未熟児合併症の治療及び/又は予防の方法と製品 Download PDF

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JP5449134B2
JP5449134B2 JP2010504018A JP2010504018A JP5449134B2 JP 5449134 B2 JP5449134 B2 JP 5449134B2 JP 2010504018 A JP2010504018 A JP 2010504018A JP 2010504018 A JP2010504018 A JP 2010504018A JP 5449134 B2 JP5449134 B2 JP 5449134B2
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アン・ヘルストレム
カタリーナ・レーフクヴィスト
ロイス・スミス
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プレーマクレ・アクチエボラーグ
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754Insulin-like growth factor binding proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
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    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010504018A 2007-04-18 2008-04-18 未熟児合併症の治療及び/又は予防の方法と製品 Active JP5449134B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92396307P 2007-04-18 2007-04-18
US60/923,963 2007-04-18
PCT/SE2008/050441 WO2008130315A1 (en) 2007-04-18 2008-04-18 Method and product for treatment and/or prevention of complications of prematurity

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JP2013189927A Division JP2013249317A (ja) 2007-04-18 2013-09-13 未熟児合併症の治療及び/又は予防の方法と製品

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JP2010524928A JP2010524928A (ja) 2010-07-22
JP2010524928A5 JP2010524928A5 (https=) 2011-05-12
JP5449134B2 true JP5449134B2 (ja) 2014-03-19

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JP2013189927A Pending JP2013249317A (ja) 2007-04-18 2013-09-13 未熟児合併症の治療及び/又は予防の方法と製品

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US (3) US8518877B2 (https=)
EP (1) EP2148695B1 (https=)
JP (2) JP5449134B2 (https=)
CN (1) CN101969983B (https=)
WO (1) WO2008130315A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013249317A (ja) * 2007-04-18 2013-12-12 Premacure Ab 未熟児合併症の治療及び/又は予防の方法と製品

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6284341B2 (ja) 2012-10-24 2018-02-28 国立大学法人東京農工大学 未熟児網膜症の治療又は予防剤、未熟児網膜症の検査方法及び未熟児網膜症の治療又は予防物質のスクリーニング方法
US9510055B2 (en) 2013-01-23 2016-11-29 Sonos, Inc. System and method for a media experience social interface
US20150220498A1 (en) 2014-02-05 2015-08-06 Sonos, Inc. Remote Creation of a Playback Queue for a Future Event
US9679054B2 (en) 2014-03-05 2017-06-13 Sonos, Inc. Webpage media playback
US20150324552A1 (en) 2014-05-12 2015-11-12 Sonos, Inc. Share Restriction for Media Items
US20150356084A1 (en) 2014-06-05 2015-12-10 Sonos, Inc. Social Queue
US9874997B2 (en) 2014-08-08 2018-01-23 Sonos, Inc. Social playback queues
EP3114852A1 (en) 2014-09-24 2017-01-11 Sonos Inc. Social media queue
WO2016049342A1 (en) 2014-09-24 2016-03-31 Sonos, Inc. Social media connection recommendations based on playback information
US9959087B2 (en) 2014-09-24 2018-05-01 Sonos, Inc. Media item context from social media
US10645130B2 (en) 2014-09-24 2020-05-05 Sonos, Inc. Playback updates
US9690540B2 (en) 2014-09-24 2017-06-27 Sonos, Inc. Social media queue
US9860286B2 (en) 2014-09-24 2018-01-02 Sonos, Inc. Associating a captured image with a media item
US9667679B2 (en) 2014-09-24 2017-05-30 Sonos, Inc. Indicating an association between a social-media account and a media playback system
US9723038B2 (en) 2014-09-24 2017-08-01 Sonos, Inc. Social media connection recommendations based on playback information
WO2018093797A1 (en) * 2016-11-15 2018-05-24 The Schepens Eye Research Institute, Inc. Compositions and methods for the treatment of aberrant angiogenesis
EP4663184A3 (en) * 2017-09-11 2026-03-18 Oak Hill Bio Limited Compositions for reducing the incidence of bpd
WO2019099560A1 (en) 2017-11-14 2019-05-23 The Schepens Eye Research Institute, Inc. Runx1 inhibition for treatment of proliferative vitreoretinopathy and conditions associated with epithelial to mesenchymal transition
CN114126640B (zh) * 2019-05-28 2024-10-29 爱儿安制药有限公司 治疗视网膜病变的组合物和方法
WO2023242442A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Method of maturing/differentiating neurons and/or modulating the vagus nerve
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
EP4598630A1 (en) * 2022-10-04 2025-08-13 Oak Hill Bio Limited Method of treating neonates with igf-1 complex
WO2024160999A1 (en) * 2023-02-03 2024-08-08 Oak Hill Bio Limited Treatment of kidney injury with igf-1 complex
WO2024170612A1 (en) * 2023-02-14 2024-08-22 Oak Hill Bio Limited Treatment of healing dysregulation in gi tissue

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
US5187151A (en) * 1991-02-12 1993-02-16 Genentech, Inc. Use of binding protein with igf-i as an anabolic growth promoting agent
JPH07508025A (ja) * 1992-05-08 1995-09-07 トーマス・ジェファーソン・ユニバーシティ インスリン様増殖因子(igf−1)類似体
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6040292A (en) * 1999-06-04 2000-03-21 Celtrix Pharmaceuticals, Inc. Methods for treating diabetes
DE60143858D1 (de) 2000-11-28 2011-02-24 Premacure Ab Reduzierung DES RISIKOS FÜR KOMPLIKATIONEN BEI FRÜHGEBURTEN
EP1906969A4 (en) * 2005-07-15 2009-07-29 Childrens Medical Center METHOD FOR TREATING AND DIAGNOSIS OF COMPLICATIONS IN AN EARLY BIRTH
EP2148695B1 (en) * 2007-04-18 2014-10-15 Premacure AB Method and product for treatment and/or prevention of complications of prematurity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013249317A (ja) * 2007-04-18 2013-12-12 Premacure Ab 未熟児合併症の治療及び/又は予防の方法と製品

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JP2013249317A (ja) 2013-12-12
US9463222B2 (en) 2016-10-11
EP2148695A1 (en) 2010-02-03
EP2148695B1 (en) 2014-10-15
CN101969983B (zh) 2014-11-05
JP2010524928A (ja) 2010-07-22
US8518877B2 (en) 2013-08-27
EP2148695A4 (en) 2013-01-16
CN101969983A (zh) 2011-02-09
WO2008130315A1 (en) 2008-10-30
US20130310316A1 (en) 2013-11-21
US20100204101A1 (en) 2010-08-12
US20150216943A1 (en) 2015-08-06

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