JP5420669B2 - 皮膚または毛髪の色素沈着の検討または調節に有用な方法、組成物で使用するための植物抽出物、および化粧的ケアの方法 - Google Patents

皮膚または毛髪の色素沈着の検討または調節に有用な方法、組成物で使用するための植物抽出物、および化粧的ケアの方法 Download PDF

Info

Publication number
JP5420669B2
JP5420669B2 JP2011526484A JP2011526484A JP5420669B2 JP 5420669 B2 JP5420669 B2 JP 5420669B2 JP 2011526484 A JP2011526484 A JP 2011526484A JP 2011526484 A JP2011526484 A JP 2011526484A JP 5420669 B2 JP5420669 B2 JP 5420669B2
Authority
JP
Japan
Prior art keywords
myo
extract
skin
melanin
melanocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2011526484A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012502289A5 (enExample
JP2012502289A (ja
Inventor
ロビン、クルフュルス
カリーヌ、ニザル
シルビアンヌ、シュネベール
エリック、ペリエ
デスモンド、ジェイ．トービン
スマン、ケイ、シン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LVMH Recherche GIE
Original Assignee
LVMH Recherche GIE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0816507.8A external-priority patent/GB0816507D0/en
Priority claimed from EP09290446A external-priority patent/EP2260831A1/en
Application filed by LVMH Recherche GIE filed Critical LVMH Recherche GIE
Publication of JP2012502289A publication Critical patent/JP2012502289A/ja
Publication of JP2012502289A5 publication Critical patent/JP2012502289A5/ja
Application granted granted Critical
Publication of JP5420669B2 publication Critical patent/JP5420669B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9741—Pteridophyta [ferns]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9794—Liliopsida [monocotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/08—Preparations for bleaching the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2011526484A 2008-09-10 2009-09-09 皮膚または毛髪の色素沈着の検討または調節に有用な方法、組成物で使用するための植物抽出物、および化粧的ケアの方法 Active JP5420669B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0816507.8 2008-09-10
GBGB0816507.8A GB0816507D0 (en) 2008-09-10 2008-09-10 Product and method
EP09290446.5 2009-06-12
EP09290446A EP2260831A1 (en) 2009-06-12 2009-06-12 Plant extracts modulating Myo-X for use in compositions
PCT/EP2009/061712 WO2010029115A1 (en) 2008-09-10 2009-09-09 Methods useful in studying or modulating skin or hair pigmentation, plant extracts for use in compositions and cosmetic care method

Publications (3)

Publication Number Publication Date
JP2012502289A JP2012502289A (ja) 2012-01-26
JP2012502289A5 JP2012502289A5 (enExample) 2013-11-14
JP5420669B2 true JP5420669B2 (ja) 2014-02-19

Family

ID=41319738

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011526484A Active JP5420669B2 (ja) 2008-09-10 2009-09-09 皮膚または毛髪の色素沈着の検討または調節に有用な方法、組成物で使用するための植物抽出物、および化粧的ケアの方法

Country Status (6)

Country Link
US (2) US8409633B2 (enExample)
EP (2) EP3628306A1 (enExample)
JP (1) JP5420669B2 (enExample)
KR (1) KR101494375B1 (enExample)
ES (1) ES2753887T3 (enExample)
WO (1) WO2010029115A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5663141B2 (ja) * 2009-02-26 2015-02-04 花王株式会社 皮膚色改変剤、毛色改変剤及びフェオメラニン産生促進剤
EP3804693B1 (en) 2010-10-19 2025-12-03 Symrise AG Extracts of chaetoceros sp. and their application
US9233062B2 (en) 2011-05-10 2016-01-12 Mary Kay Inc. Cosmetic compositions
EP2831274B1 (en) * 2012-03-30 2017-12-13 The Procter and Gamble Company Method of constructing a data architecture for use in identifying agents for skin pigmentation
WO2016007601A1 (en) 2014-07-11 2016-01-14 Mary Kay Inc. Pore minimizer
KR102348045B1 (ko) 2015-02-27 2022-01-11 (주)아모레퍼시픽 미백성분의 부작용을 예측하는 방법
KR20170091456A (ko) * 2016-02-01 2017-08-09 주식회사 파이안바이오테크놀로지 식물유래 유전자 절편 혼합물 제조 방법 및 이를 함유하는 비수계 조성물
CN119235680A (zh) * 2024-09-23 2025-01-03 广州市清扬精细化工有限公司 一种养发护发的复合单剂型黑色素前体物质染发剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4815616B1 (enExample) * 1969-05-19 1973-05-16
JPH08127517A (ja) * 1994-10-27 1996-05-21 Hiroichi Hagiwara 育毛・抜毛防止剤の製法
US6171593B1 (en) * 1994-11-10 2001-01-09 Johnny L. Williams Method of treating skin disorders using an extract of mullein
US5866150A (en) * 1996-03-20 1999-02-02 Aquaculture Technology Incorporated Antibacterially active extracts from the marine algae chaetoceros and methods of use
US8093293B2 (en) * 1998-07-06 2012-01-10 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin conditions
US6750229B2 (en) * 1998-07-06 2004-06-15 Johnson & Johnson Consumer Companies, Inc. Methods for treating skin pigmentation
JP4713032B2 (ja) 2001-09-20 2011-06-29 株式会社コーセー 皮膚外用剤
JP2003246722A (ja) * 2002-02-25 2003-09-02 Kanebo Ltd 美白化粧料
DE50306943D1 (de) * 2003-08-20 2007-05-10 Riemschneider Randolph Pflanzliche plazenta-extrakte, verfahren zu ihrer herstellung und ihre verwendung
JP2006069967A (ja) * 2004-09-02 2006-03-16 Yukihiro Hirose 白髪抑制用組成物およびそれを含有する化粧料及び飲食タイプの化粧料
GB0421937D0 (en) * 2004-10-02 2004-11-03 Univ York Acyl CoA synthetases
DE102005033758A1 (de) 2005-07-15 2007-01-18 Jürgens, Gabriela Orthopädische Vorrichtung
FR2894582B1 (fr) * 2005-12-12 2008-02-22 Fabre Pierre Dermo Cosmetique Sirna anti myosine va et depigmentation de la peau
JP2007204449A (ja) * 2006-02-03 2007-08-16 Pias Arise Kk マトリックスメタロプロテアーゼ−９及びエンドセリン−１の産生抑制剤、並びにその産生抑制剤を配合した炎症後色素沈着の予防・改善剤、化粧料
JPWO2007094030A1 (ja) 2006-02-13 2009-07-02 株式会社坂本バイオ 美白剤
AR059545A1 (es) * 2006-02-28 2008-04-09 Bayer Consumer Care Ag Combinacion de verbacosido y luteolina
WO2008015342A2 (fr) 2006-08-03 2008-02-07 Societe D'extraction Des Principes Actifs Sa (Vincience) Utilisation d'un extrait vegetal en tant qu'agent actif pour augmenter la synthese de melanine dans les melanocytes

Also Published As

Publication number Publication date
US9668960B2 (en) 2017-06-06
EP2334282A1 (en) 2011-06-22
KR101494375B1 (ko) 2015-02-17
US20130177512A1 (en) 2013-07-11
US20110229431A1 (en) 2011-09-22
EP3628306A1 (en) 2020-04-01
EP2334282B1 (en) 2019-08-07
WO2010029115A1 (en) 2010-03-18
ES2753887T3 (es) 2020-04-14
KR20110069059A (ko) 2011-06-22
JP2012502289A (ja) 2012-01-26
US8409633B2 (en) 2013-04-02
US20140044651A2 (en) 2014-02-13

Similar Documents

Publication Publication Date Title
JP5420669B2 (ja) 皮膚または毛髪の色素沈着の検討または調節に有用な方法、組成物で使用するための植物抽出物、および化粧的ケアの方法
EP1515688B1 (fr) Utilisation d'un complexe salen-manganèse comme agent protecteur des mélanocytes du follicule pileux et applications cosmétiques
JP6584494B2 (ja) メラニン産生細胞のｈｍｇｂ１活性化を阻害する方法、そのような阻害に好適な薬剤を特定する方法
JP2024134554A (ja) 毛髪ケア活性剤
US20160095815A1 (en) Substance for restoring normal co-expression and interaction between the lox and nrage proteins
Kim et al. N-nicotinoyl tyramine, a novel niacinamide derivative, inhibits melanogenesis by suppressing MITF gene expression
JP6517328B2 (ja) 皮膚の老化の防止および／または緩和、および／または皮膚の保湿、および／または皮膚色素沈着の抑制のためのセストリン（ｓｅｓｔｒｉｎ）アクチベーター
JP5730462B2 (ja) 白髪を処理するための、メラニン形成細胞内のグルタチオンレベルを増大させることが可能な化合物の使用
JP7016533B2 (ja) 白斑毒性及び黒皮症毒性の試験方法
EP1515687A2 (fr) Utilisation d'un agent inducteur de l'expression de la dopachrome tautomerase (trp-2) comme agent protecteur des melanocytes du follicule pileux
EP2260831A1 (en) Plant extracts modulating Myo-X for use in compositions
US9326927B2 (en) Use of cannabinoid compounds for stimulating melanogenesis
Class et al. Patent application title: METHODS USEFUL IN STUDYING OR MODULATING SKIN OR HAIR PIGMENTATION, PLANT EXTRACTS FOR USE IN COMPOSITIONS AND COSMETIC CARE METHOD Inventors: Robin Kurfurst (Saint Jean De Braye, FR) Robin Kurfurst (Saint Jean De Braye, FR) Carine Nizard (Ivry Sur Seine, FR) Carine Nizard (Ivry Sur Seine, FR) Sylvianne Schnebert (Olivet, FR) Eric Perrier (Les Cotes D'Arey, FR) Desmond J. Tobin (West Yorkshire, GB) Suman K. Singh (Jharkhand Jamshedpur, IN)
HK1158982A (en) Methods useful in studying or modulating skin or hair pigmentation, plant extracts for use in compositions and cosmetic care method
HK1158982B (en) Methods useful in studying or modulating skin or hair pigmentation, plant extracts for use in compositions and cosmetic care method
JP2024055618A (ja) シミ及び色むら評価方法及びこれを用いた美白外用剤有効成分選定方法、美白方法、並びに、美白外用剤
TW201424766A (zh) Ｐｌｏｄ－２調節劑及其於皮膚治療之用途
FR2863484A1 (fr) Utilisation de composes capables d'agir sur la voie metabolique controlee par la dopachrome tautomerase trp-2 comme agent protecteur des melanocytes du follicule pileux et applications

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120709

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120709

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130930

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20130930

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20131010

TRDD Decision of grant or rejection written
A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20131011

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20131022

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20131120

R150 Certificate of patent or registration of utility model

Ref document number: 5420669

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250