JP5410985B2 - 液体抗狂犬病抗体製剤 - Google Patents
液体抗狂犬病抗体製剤 Download PDFInfo
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
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| US87289206P | 2006-12-05 | 2006-12-05 | |
| EP06125400.9 | 2006-12-05 | ||
| US60/872,892 | 2006-12-05 | ||
| EP06125400 | 2006-12-05 | ||
| PCT/EP2007/063244 WO2008068246A1 (en) | 2006-12-05 | 2007-12-04 | Liquid anti-rabies antibody formulations |
Publications (3)
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| JP2010511665A JP2010511665A (ja) | 2010-04-15 |
| JP2010511665A5 JP2010511665A5 (enExample) | 2011-01-20 |
| JP5410985B2 true JP5410985B2 (ja) | 2014-02-05 |
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| JP2009539730A Expired - Fee Related JP5410985B2 (ja) | 2006-12-05 | 2007-12-04 | 液体抗狂犬病抗体製剤 |
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| EP (1) | EP2088997B1 (enExample) |
| JP (1) | JP5410985B2 (enExample) |
| KR (1) | KR101522036B1 (enExample) |
| CN (1) | CN101557799B (enExample) |
| AU (1) | AU2007328960B2 (enExample) |
| CA (1) | CA2668947C (enExample) |
| CU (1) | CU23795A3 (enExample) |
| EA (1) | EA017549B1 (enExample) |
| IL (1) | IL199004A (enExample) |
| MX (1) | MX2009005414A (enExample) |
| WO (1) | WO2008068246A1 (enExample) |
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Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2526284C (en) | 2003-06-25 | 2014-11-18 | Crucell Holland B.V. | Binding molecules for the treatment of myeloid cell malignancies |
| PL2314621T3 (pl) * | 2004-05-27 | 2014-08-29 | Crucell Holland Bv | Cząsteczki wiążące zdolne do neutralizowania wirusa wścieklizny i ich zastosowania |
| CA2881717C (en) | 2006-06-06 | 2018-06-12 | Cecilia Anna Wilhelmina Geuijen | Human binding molecules having killing activity against staphylococci and uses thereof |
| CN101557799B (zh) | 2006-12-05 | 2012-08-22 | 克鲁塞尔荷兰公司 | 液体抗狂犬病抗体制剂 |
| JP2010085126A (ja) * | 2008-09-29 | 2010-04-15 | Adtec Kk | 狂犬病ウイルス中和抗体価判定具および狂犬病ウイルス中和抗体価の測定方法 |
| WO2011028961A2 (en) | 2009-09-04 | 2011-03-10 | Xoma Technology Ltd. | Anti-botulism antibody coformulations |
| US9089529B2 (en) | 2011-10-25 | 2015-07-28 | Prothena Therapeutics Limited | Antibody formulations and methods |
| US9376491B2 (en) * | 2012-03-07 | 2016-06-28 | Eli Lilly And Company | IL-17 antibody formulation and method of treatment using same |
| UA117466C2 (uk) | 2012-12-13 | 2018-08-10 | Мерк Шарп Енд Доме Корп. | СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19 |
| KR20140119396A (ko) | 2013-03-29 | 2014-10-10 | 삼성전자주식회사 | 단백질 약물의 액상 제형 |
| JOP20190260A1 (ar) | 2017-05-02 | 2019-10-31 | Merck Sharp & Dohme | صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها |
| BR112019022873A8 (pt) | 2017-05-02 | 2023-04-11 | Merck Sharp & Dohme | Formulação, e, vaso ou dispositivo de injeção. |
| JP7159642B2 (ja) * | 2018-06-26 | 2022-10-25 | 東ソー株式会社 | カラムの抗体に対する保持力の測定方法 |
| CN113316458B (zh) | 2018-11-07 | 2024-08-02 | 默沙东有限责任公司 | 抗lag3抗体和抗pd-1抗体的共制剂 |
| WO2021249542A1 (en) | 2020-06-12 | 2021-12-16 | Nanjing Leads Biolabs Co., Ltd. | Antibodies binding tnfr2 and uses thereof |
| CN119405798A (zh) * | 2022-04-02 | 2025-02-11 | 重庆智翔金泰生物制药股份有限公司 | 一种治疗狂犬病的抗体药物组合物及其制备方法 |
| CN117771365B (zh) * | 2023-12-07 | 2025-07-04 | 兰州生物制品研究所有限责任公司 | 一种抗狂犬病病毒组合单克隆抗体制剂 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE99958T1 (de) | 1989-06-08 | 1994-01-15 | Wistar Inst | Monoklonale antikoerper zur behandlung nach einem kontakt mit tollwutvirus. |
| DE4006630A1 (de) | 1990-03-03 | 1991-09-12 | Behringwerke Ag | Humane monoklonale antikoerper gegen tollwutviren, ihre herstellung und verwendung |
| CA2267139A1 (en) | 1996-10-08 | 1998-04-16 | Ton Logtenberg | Methods and means for selecting peptides and proteins having specific affinity for a target |
| US20040013672A1 (en) | 2000-05-16 | 2004-01-22 | Thomas Jefferson University | Recombinant antibodies, and compositions and methods for making and using the same |
| NZ531291A (en) | 2001-08-21 | 2006-02-24 | Univ Jefferson | Recombinant anti rabies antibodies MAb JB.1 and Mab 57 and compositions and methods for making and using the same |
| PT2314629E (pt) | 2002-07-18 | 2014-01-22 | Merus B V | Produção recombinante de misturas de anticorpos |
| WO2005023849A2 (en) | 2003-09-04 | 2005-03-17 | Crucell Holland B.V. | Antigenic peptides of rabies virus and uses thereof |
| EP1686137A4 (en) * | 2003-10-09 | 2009-10-28 | Chugai Pharmaceutical Co Ltd | PROCESS FOR STABILIZING PROTEIN SOLUTIONS |
| US20070212346A1 (en) * | 2003-10-09 | 2007-09-13 | Tomoyuki Igawa | Highly Concentrated Stabilized Igm Solution |
| JPWO2005063291A1 (ja) * | 2003-12-25 | 2007-07-19 | 麒麟麦酒株式会社 | 抗体を含有する安定な水性医薬製剤 |
| PL2314621T3 (pl) * | 2004-05-27 | 2014-08-29 | Crucell Holland Bv | Cząsteczki wiążące zdolne do neutralizowania wirusa wścieklizny i ich zastosowania |
| CA2604840A1 (en) * | 2005-04-18 | 2006-10-26 | Xtl Biopharmaceuticals Ltd. | Stabilized anti-hepatitis b (hbv) antibody formulations |
| CN101557799B (zh) | 2006-12-05 | 2012-08-22 | 克鲁塞尔荷兰公司 | 液体抗狂犬病抗体制剂 |
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2007
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- 2007-12-04 JP JP2009539730A patent/JP5410985B2/ja not_active Expired - Fee Related
- 2007-12-04 WO PCT/EP2007/063244 patent/WO2008068246A1/en not_active Ceased
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- 2007-12-04 EP EP07847749.4A patent/EP2088997B1/en active Active
- 2007-12-04 KR KR1020097013012A patent/KR101522036B1/ko not_active Expired - Fee Related
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2009
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- 2009-05-27 IL IL199004A patent/IL199004A/en active IP Right Grant
- 2009-06-04 CU CU20090099A patent/CU23795A3/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101557799B (zh) | 2012-08-22 |
| MX2009005414A (es) | 2009-06-01 |
| CA2668947A1 (en) | 2008-06-12 |
| JP2010511665A (ja) | 2010-04-15 |
| EP2088997B1 (en) | 2016-08-24 |
| EP2088997A1 (en) | 2009-08-19 |
| AU2007328960A1 (en) | 2008-06-12 |
| KR20090089881A (ko) | 2009-08-24 |
| CA2668947C (en) | 2017-02-07 |
| IL199004A0 (en) | 2010-02-17 |
| ZA200902772B (en) | 2012-09-26 |
| CN101557799A (zh) | 2009-10-14 |
| EA200970533A1 (ru) | 2009-10-30 |
| KR101522036B1 (ko) | 2015-05-20 |
| US20100034829A1 (en) | 2010-02-11 |
| CU23795A3 (es) | 2012-03-15 |
| WO2008068246A1 (en) | 2008-06-12 |
| AU2007328960B2 (en) | 2013-01-17 |
| EA017549B1 (ru) | 2013-01-30 |
| US7959922B2 (en) | 2011-06-14 |
| IL199004A (en) | 2015-10-29 |
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