JP5409985B2 - 微生物を制御するための徐放性を有する組成物 - Google Patents
微生物を制御するための徐放性を有する組成物 Download PDFInfo
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- JP5409985B2 JP5409985B2 JP2005276462A JP2005276462A JP5409985B2 JP 5409985 B2 JP5409985 B2 JP 5409985B2 JP 2005276462 A JP2005276462 A JP 2005276462A JP 2005276462 A JP2005276462 A JP 2005276462A JP 5409985 B2 JP5409985 B2 JP 5409985B2
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- polyglycerol
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- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- SUMDYPCJJOFFON-UHFFFAOYSA-N isethionic acid Chemical compound OCCS(O)(=O)=O SUMDYPCJJOFFON-UHFFFAOYSA-N 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000008268 mayonnaise Substances 0.000 description 1
- 235000010746 mayonnaise Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 238000012009 microbiological test Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- SFBIZPBTKROSDE-UHFFFAOYSA-N octyl 2-hydroxypropanoate Chemical compound CCCCCCCCOC(=O)C(C)O SFBIZPBTKROSDE-UHFFFAOYSA-N 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 150000004967 organic peroxy acids Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000003973 paint Substances 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920000233 poly(alkylene oxides) Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 229910000027 potassium carbonate Inorganic materials 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 229940043230 sarcosine Drugs 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 231100000370 skin sensitisation Toxicity 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- JYKSTGLAIMQDRA-UHFFFAOYSA-N tetraglycerol Chemical compound OCC(O)CO.OCC(O)CO.OCC(O)CO.OCC(O)CO JYKSTGLAIMQDRA-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- DHCDFWKWKRSZHF-UHFFFAOYSA-L thiosulfate(2-) Chemical compound [O-]S([S-])(=O)=O DHCDFWKWKRSZHF-UHFFFAOYSA-L 0.000 description 1
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229960003500 triclosan Drugs 0.000 description 1
- 150000005691 triesters Chemical class 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-O triethanolammonium Chemical class OCC[NH+](CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-O 0.000 description 1
- 229960002703 undecylenic acid Drugs 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
- A23L3/3517—Carboxylic acid esters
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group, wherein Cn means a carbon skeleton not containing a ring; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3562—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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Description
HO−CH2−CH(OH)−CH2−O−[CH2−CH(OH)−CH2−O]n−H
(式中、nは0〜9、好ましくは1〜6、特に1〜3、具体的には1および2)のポリグリセロールが好ましい。さらに、使用されるポリグリセロールは分岐していても環式部分を含んでいてもよい。
1.アルキレンオキシド系非イオン性界面活性剤、例えば、長鎖分岐アルコールのエトキシレート、ソルビタンエステルのエトキシレート、プロピレンオキシド−エチレンオキシドコポリマー、ヒドロキシアルキル脂肪酸アミド、ポリジメチルシロキサンポリアルキレンオキシドコポリマー、糖系界面活性剤(アルキルポリグリコシド、アルキルグリコシドエステル、N−アシルグルカミド等)、およびポリグリセロールエステル、
2.アニオン性界面活性剤、例えば、アルキル硫酸エステル塩およびアルキルエーテル硫酸エステル塩、a−オレフィンスルホン酸塩、脂肪酸エステルスルホン酸塩、アルキルアリールスルホン酸塩、スルホコハク酸塩、アルキルまたはアルコキシアルキルリン酸エステル塩、酒石酸塩、N−アシルアミノ酸誘導体、サルコシン酸塩、イセチオン酸塩、および石鹸
3.カチオン性界面活性剤、例えば、アルキルトリメチルアンモニウム塩、ジ−およびトリエタノールアンモニウム塩の脂肪酸エステル、アルキルイミダゾリニウム塩、アシルアミドプロピルジメチルアンモニウム塩、ポリジメチルシロキサンのカチオン性誘導体、
4.両イオン性および両性界面活性剤、例えば、ベタイン、スルホベタイン、アミンオキシド、およびアンホ酢酸塩。
本発明による生成物の効果を負荷試験(欧州製薬指導(European Pharmaceuticals Directive)に準ずる)を用いて確認する。これにより、本発明による生成物は従来技術と比較してはるかに優れていることがわかる。
A)対コリネバクテリウム・キセロシス(Corynebacterium xerosis)、スタフィロコッカス・エピデルミディス(表皮ブドウ球菌、Staphylococcus epidermidis)、カンジダ・アルビカンス(Candida albicans)
1.1.試料
a.ジグリセロールカプリル酸エステル(従来技術による比較用物質)
b.ジグリセロールカプリル酸エステルおよびカプリル酸カリウム5%
c.ジグリセロールカプリル酸エステルおよびカプリル酸カリウム10%
d.ジグリセロールカプリル酸エステルおよびカプリル酸カリウム15%
e.ポリグリセロール−3カプリル酸エステル
f.ポリグリセロール−3カプリル酸エステルおよびカプリル酸カリウム7%
g.トリエチレングリコールカプリル酸エステル
h.トリエチレングリコールカプリル酸エステルおよびカプリル酸カリウム5%
i.カプリル酸ソルビタン
j.カプリル酸ソルビタンおよびカプリル酸カリウム5%
コリネバクテリウム・キセロシス DSM 20743
スタフィロコッカス・エピデルミディス DSM 3269
カンジダ・アルビカンス ATCC 10231
栄養培地:
CSL:カゼインペプトン−大豆粉ペプトン溶液
CSA:カゼインペプトン−大豆粉ペプトン溶液−寒天
サブローグルコースブロス/寒天
不活性化剤を添加した希釈液:
不活性化剤(トゥイーン(Tween)(登録商標)80を3%、レシチン0.3%、ヒスチジン0.1%、チオ硫酸Na0.5%)加NaClペプトン緩衝液
2.1.試験液の調製
検査前日、各試料から試験液(CSL中、0.1%(w/v))を調製した。このために、それぞれの場合ごとにCSL100mlを湯浴で60℃に加熱し、それぞれの場合ごとに各試料0.1gを秤量して60℃のCSL100ml中に加えた。この調製液を手で激しく振り、30℃のインキュベータ内に一夜放置した。
コリネバクテリウム・キセロシスを3〜4日超培養する。他の微生物をブロス中に、またはエルトリエーションによって単離する。
各試験用微生物ごとに、各試験液20mlをガラスビーズを含む50mlの茶色の滅菌ガラス瓶に導入し、微生物懸濁液0.2mlで汚染した。対照として、試料を含まないCSL20mlも試験用微生物ごとに調製した。汚染された試料を振とう機で3分間振とうした後、インキュベータに入れ、これを取り出すまで30℃に維持した。
以下のグラフに個々の試料に関する結果を示す。有効成分を含まないブランク試料の24時間培養後の菌数も(単独の)対照値として各グラフにプロットした。
Aに記載した手順と同様にして、カプリル酸カリウム7%を含むジグリセロールカプリル酸エステルのマラセチア・フルフルに対する効果を試験した。M・フルフルはフケ形成の原因に関与している。
本発明による生成物を使用し得る配合例を以下に示す。
防臭スプレー(本発明による)
防臭スプレー(本発明によらない)
透明防臭ポンプスプレー
O/Wエマルジョン(スプレー可能)
相Aを先に導入する場合は、相Bは撹拌せずに添加すること。
透明防臭ロールオン
透明防臭ロールオン
AP/防臭スティック
透明防臭ポンプスプレー
アニオン性家庭用洗剤(濃縮)
液体石鹸
練り歯磨き
フケ取りシャンプー
2種類の配合物を用いる。これらを配合物1および2とする。この配合物を熟練者3人によって被験者20人に適用し、その前後の腋臭を調査する。詳細には、この試験は以下の手順を含む。
1.腋窩を石鹸で洗浄し、熟練者が臭いを評価する。
2.片方の腋窩に当該生成物を1回適用する。6および24時間後に臭いを調査し、その差を評価する。
加熱後に細かく刻んだジャガイモ750g、細かく刻んだ玉ねぎ25g、調理塩1.2g、酢(酢酸6%を含む)10ml、およびマヨネーズ200gからなるポテトサラダを、配合4のポリグリセロールエステル0.5%で処理した。細菌および酵母を検査するため、このポテトサラダを30℃で72時間保管した。その後の計測により、以下の微生物数を得た。
1.2×106微生物数/ml
ポテトサラダ、ポリグリセロールエステル使用
1.3×103微生物数/ml
6.7×104微生物数/ml
ポテトサラダ、ポリグリセロールエステル使用
2.5×101微生物数/ml
Claims (13)
- ポリグリセロールカプリル酸エステルと、カプリル酸および/またはその塩との混合物を有効量含有する、抗菌効果を有する微生物制御組成物であって、
前記ポリグリセロールが、下記一般式で表され、
HO−CH2−CH(OH)−CH2−O−[CH2−CH(OH)−CH2−O]n−H
(式中、nは1〜9である。)
前記ポリグリセロールカプリル酸エステル対前記カプリル酸および/またはその塩の比が80:20〜99:1の範囲にある、微生物制御組成物。 - 前記ポリグリセロールカプリル酸エステルが、ジ−、および/またはトリグリセロールのモノエステルおよびジエステルである、請求項1に記載の組成物。
- 前記ポリグリセロールが、下記一般式で表される、
HO−CH2−CH(OH)−CH2−O−[CH2−CH(OH)−CH2−O]n−H
(式中、nは1〜6である。)
請求項1または2に記載の組成物。 - グラム陽性菌、グラム陰性菌、マイコバクテリウム、皮膚糸状菌、酵母および糸状菌、ウイルス、ならびに胞子を制御するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- コリネバクテリウム・キセロシス、スタフィロコッカス・エピデルミディスおよびカンジダ・アルビカンスから選択される微生物を制御するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- コリネバクテリウム・キセロシスを制御するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- 消毒剤、消毒洗浄剤、滅菌用組成物、殺菌剤、および防腐剤を製造するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- 食品を保存するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- 内容物の保存期間を延長するべく食品包装を抗菌仕上げするための、請求項1〜3のいずれか1項に記載の組成物の使用。
- 身体洗浄および身体手入れ分野用の化粧料を製造するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- 体臭を防ぎ、かつフケの形成を防ぐ化粧料を製造するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- にきび肌および軽症のにきびを防ぐ化粧料を製造するための、請求項1〜3のいずれか1項に記載の組成物の使用。
- 練り歯磨き、口腔洗浄液等の歯の手入れ用品を製造するための、請求項1〜3のいずれか1項に記載の組成物の使用。
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DE102004046603A DE102004046603A1 (de) | 2004-09-25 | 2004-09-25 | Mittel mit Depotwirkung zur Bekämpfung von Mikroorganismen |
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CN (1) | CN100518505C (ja) |
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DE10120927A1 (de) * | 2001-04-30 | 2002-10-31 | Stockhausen Chem Fab Gmbh | Verwendung von multiplen Emulsionen als Hautschutzprodukte |
PL1668105T3 (pl) | 2003-09-29 | 2019-03-29 | Deb Ip Limited | Kompozycje żelopodobne i pieniące o dużej zawartości alkoholu |
DE102004026684A1 (de) * | 2004-05-28 | 2005-12-29 | Stockhausen Gmbh | Hautreinigungsmittel, insbesondere zur Entfernung von Druckfarben und/oder Tintenverschmutzungen |
JP4578943B2 (ja) * | 2004-11-15 | 2010-11-10 | 花王株式会社 | 農薬組成物 |
DE102004062775A1 (de) | 2004-12-21 | 2006-06-29 | Stockhausen Gmbh | Alkoholischer Pumpschaum |
JP2008531740A (ja) | 2005-03-07 | 2008-08-14 | デブ ワールドワイド ヘルスケア インコーポレーテッド | シリコーン・ベースの界面活性剤を含むアルコール含有量の高い発泡性組成物 |
US7651990B2 (en) * | 2005-06-13 | 2010-01-26 | 3M Innovative Properties Company | Foamable alcohol compositions comprising alcohol and a silicone surfactant, systems and methods of use |
DE102006053360A1 (de) * | 2006-11-10 | 2008-05-15 | Evonik Stockhausen Gmbh | Hautreinigungsmittel, insbesondere Kälteschutzcreme |
DE102006053500A1 (de) | 2006-11-14 | 2008-05-15 | Evonik Goldschmidt Gmbh | Antimikrobielle Zusammensetzungen |
DE102007022693A1 (de) * | 2007-05-11 | 2009-01-15 | Evonik Stockhausen Gmbh | Haut- und Händereinigungsmittel mit hydrophilen Emollients |
EP2000124A1 (en) | 2007-06-08 | 2008-12-10 | Evonik Goldschmidt GmbH | Cosmetic and pharmaceutical oil-in-water emulsions containing an ester quat |
JP2010163397A (ja) * | 2009-01-16 | 2010-07-29 | Japan Ecologia Co Ltd | 抗菌性組成物 |
DE102009028143A1 (de) | 2009-07-31 | 2011-02-03 | Evonik Stockhausen Gmbh | Hautschutzmittel, insbesondere gegen hydrophobe (lipophile) als auch gegen hydrophile (lipophobe) Schadstoffe |
DE102009028156A1 (de) | 2009-07-31 | 2011-02-03 | Evonik Stockhausen Gmbh | Schäumbare O/W-Emulsion |
JP5948903B2 (ja) * | 2011-02-10 | 2016-07-06 | ライオン株式会社 | 歯磨剤組成物及び歯磨剤組成物の防腐力向上方法 |
DE102011004815A1 (de) | 2011-02-28 | 2012-08-30 | Evonik Stockhausen Gmbh | Haut- und Handreinigungsmittel enthaltend superabsorbierende Partikel |
CN105188642B (zh) * | 2013-03-15 | 2018-12-07 | 高露洁-棕榄公司 | 口腔护理组合物 |
DE102013009616A1 (de) * | 2013-06-10 | 2014-12-11 | Justus-Liebig-Universität Giessen | Verwendung von Estern von gesättigten kurz- und mittelkettigen Fettsäuren zur Prophylaxe und Therapie von malassezia-assoziierten Erkrankungen und kosmetischen Problemen |
JP6242636B2 (ja) * | 2013-09-13 | 2017-12-06 | 理研ビタミン株式会社 | 腋臭原因菌に対する静菌剤 |
CN113557013A (zh) | 2019-02-04 | 2021-10-26 | 西姆莱斯有限公司 | 作为抗马拉色菌剂的脂肪酸酯 |
BR122023007839B1 (pt) | 2019-02-04 | 2024-02-27 | Symrise Ag | Uso de éster(es) de ácido graxo, método para modificar as propriedades sensoriais de um produto de cuidado com a pele e método para fabricar um produto |
BR112021015309A2 (pt) | 2019-02-04 | 2021-10-05 | Symrise Ag | Atividade antimicrobiana de ésteres de ácido graxo e combinações dos mesmos |
WO2020160743A1 (en) | 2019-02-04 | 2020-08-13 | Symrise Ag | Active agents for skin and hair care with physicochemical modifying properties |
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ES2444368T3 (es) | 2014-02-24 |
EP1652431B1 (de) | 2013-11-06 |
JP2006089483A (ja) | 2006-04-06 |
PL1652431T3 (pl) | 2014-03-31 |
EP1652431A3 (de) | 2012-02-08 |
CN1751570A (zh) | 2006-03-29 |
US20060198859A1 (en) | 2006-09-07 |
EP1652431A2 (de) | 2006-05-03 |
CN100518505C (zh) | 2009-07-29 |
BRPI0504145A (pt) | 2006-05-16 |
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DE102004046603A1 (de) | 2006-03-30 |
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