JP5362940B2 - 炎症性疾患治療用候補薬剤をスクリーニングするためのアッセイ - Google Patents

炎症性疾患治療用候補薬剤をスクリーニングするためのアッセイ Download PDF

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JP5362940B2
JP5362940B2 JP2003547968A JP2003547968A JP5362940B2 JP 5362940 B2 JP5362940 B2 JP 5362940B2 JP 2003547968 A JP2003547968 A JP 2003547968A JP 2003547968 A JP2003547968 A JP 2003547968A JP 5362940 B2 JP5362940 B2 JP 5362940B2
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cells
tetaiotaomicron
pparγ
inflammatory
caco
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JP2005510733A (ja
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デニス、ケリー
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Rowett Research Institute
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    • GPHYSICS
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
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    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
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    • A61P37/00Drugs for immunological or allergic disorders
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4703Regulators; Modulating activity
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
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JP2003547968A 2001-11-21 2002-11-20 炎症性疾患治療用候補薬剤をスクリーニングするためのアッセイ Expired - Fee Related JP5362940B2 (ja)

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GBGB0127916.5A GB0127916D0 (en) 2001-11-21 2001-11-21 Method
GB0127916.5 2001-11-21
PCT/GB2002/005255 WO2003046580A1 (en) 2001-11-21 2002-11-20 Assay for screening candidate drugs for the treatment of inflammatory diseases

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JP2012196103A Division JP2013046615A (ja) 2001-11-21 2012-09-06 炎症性疾患治療用候補薬剤をスクリーニングするためのアッセイ

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JP2005510733A JP2005510733A (ja) 2005-04-21
JP5362940B2 true JP5362940B2 (ja) 2013-12-11

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JP2012196103A Pending JP2013046615A (ja) 2001-11-21 2012-09-06 炎症性疾患治療用候補薬剤をスクリーニングするためのアッセイ

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US (1) US7998474B2 (enExample)
EP (1) EP1448995B9 (enExample)
JP (2) JP5362940B2 (enExample)
AT (1) ATE496302T1 (enExample)
AU (1) AU2002343063B2 (enExample)
CA (1) CA2468082C (enExample)
DE (1) DE60239009D1 (enExample)
DK (1) DK1448995T3 (enExample)
ES (1) ES2362494T3 (enExample)
GB (1) GB0127916D0 (enExample)
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GB0127916D0 (en) 2002-01-16
EP1448995B1 (en) 2011-01-19
US20030133875A1 (en) 2003-07-17
CA2468082C (en) 2012-06-26
AU2002343063A1 (en) 2003-06-10
WO2003046580A1 (en) 2003-06-05
DE60239009D1 (de) 2011-03-03
ATE496302T1 (de) 2011-02-15
JP2013046615A (ja) 2013-03-07
US7998474B2 (en) 2011-08-16
ES2362494T3 (es) 2012-10-05
CA2468082A1 (en) 2003-06-05
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