JP5343092B2 - 細胞分離を行う精密濾過の方法及び装置 - Google Patents
細胞分離を行う精密濾過の方法及び装置 Download PDFInfo
- Publication number
- JP5343092B2 JP5343092B2 JP2010545073A JP2010545073A JP5343092B2 JP 5343092 B2 JP5343092 B2 JP 5343092B2 JP 2010545073 A JP2010545073 A JP 2010545073A JP 2010545073 A JP2010545073 A JP 2010545073A JP 5343092 B2 JP5343092 B2 JP 5343092B2
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- Prior art keywords
- microfiltration
- porous
- membrane
- pores
- patch
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/12—Composite membranes; Ultra-thin membranes
- B01D69/1216—Three or more layers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0002—Organic membrane manufacture
- B01D67/0023—Organic membrane manufacture by inducing porosity into non porous precursor membranes
- B01D67/0032—Organic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods
- B01D67/0034—Organic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods by micromachining techniques, e.g. using masking and etching steps, photolithography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/02—Details relating to pores or porosity of the membranes
- B01D2325/021—Pore shapes
- B01D2325/0212—Symmetric or isoporous membranes
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Manufacturing & Machinery (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6281408P | 2008-01-29 | 2008-01-29 | |
| US61/062,814 | 2008-01-29 | ||
| PCT/US2009/032054 WO2009097247A1 (en) | 2008-01-29 | 2009-01-26 | Method and apparatus for microfiltration to perform cell separation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011510656A JP2011510656A (ja) | 2011-04-07 |
| JP2011510656A5 JP2011510656A5 (cg-RX-API-DMAC7.html) | 2012-03-01 |
| JP5343092B2 true JP5343092B2 (ja) | 2013-11-13 |
Family
ID=40898143
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010545073A Active JP5343092B2 (ja) | 2008-01-29 | 2009-01-26 | 細胞分離を行う精密濾過の方法及び装置 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US8114289B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2238232B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5343092B2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009097247A1 (cg-RX-API-DMAC7.html) |
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| US8980568B2 (en) * | 2001-10-11 | 2015-03-17 | Aviva Biosciences Corporation | Methods and compositions for detecting non-hematopoietic cells from a blood sample |
| US8986944B2 (en) | 2001-10-11 | 2015-03-24 | Aviva Biosciences Corporation | Methods and compositions for separating rare cells from fluid samples |
| CN101583722A (zh) | 2006-07-14 | 2009-11-18 | 阿维瓦生物科学股份有限公司 | 从生物学样品检测稀有细胞的方法和组合物 |
| JP5343092B2 (ja) | 2008-01-29 | 2013-11-13 | カリフォルニア インスティチュート オブ テクノロジー | 細胞分離を行う精密濾過の方法及び装置 |
| WO2010135603A2 (en) | 2009-05-20 | 2010-11-25 | California Institute Of Technology | Method for cancer detection, diagnosis and prognosis |
| JP5704590B2 (ja) * | 2010-02-05 | 2015-04-22 | 国立大学法人東京農工大学 | サイズ選択マイクロキャビティアレイを用いた循環腫瘍細胞の検出 |
| CN103189122B (zh) * | 2010-05-03 | 2016-11-16 | 柯丽安缇维微技术公司 | 聚合物微过滤器及其制造方法 |
| US9733235B2 (en) | 2010-05-28 | 2017-08-15 | California Instute Of Technology | Methods and design of membrane filters |
| US20110294206A1 (en) | 2010-05-28 | 2011-12-01 | California Institute Of Technology | Methods and design of membrane filters |
| US9089819B2 (en) * | 2010-09-30 | 2015-07-28 | California Institute Of Technology | Particulate nanosorting stack |
| KR101254675B1 (ko) * | 2010-10-25 | 2013-04-15 | 주식회사 싸이토젠 | 세포 채집 장치 |
| WO2012057497A2 (ko) | 2010-10-25 | 2012-05-03 | 주식회사 싸이토젠 | 세포 채집 장치 |
| WO2012151501A2 (en) * | 2011-05-05 | 2012-11-08 | Anpac Bio-Medical Science Co., Ltd. | Apparatus for detecting tumor cells |
| US8961627B2 (en) | 2011-07-07 | 2015-02-24 | David J Edlund | Hydrogen generation assemblies and hydrogen purification devices |
| US9327217B2 (en) * | 2011-09-21 | 2016-05-03 | Nanyang Technological University | Multilayer filter |
| KR101933618B1 (ko) | 2011-11-29 | 2018-12-31 | 삼성전자주식회사 | 표적 물질 검출 및 분리 장치, 및 이를 이용한 표적 물질 검출 및 분리 방법 |
| CN104093470B (zh) * | 2012-01-17 | 2016-05-11 | 宾州研究基金会 | 用于捕获液体中的颗粒或细胞的柔性过滤装置 |
| WO2013138522A2 (en) | 2012-03-16 | 2013-09-19 | Genelux Corporation | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
| TWI498273B (zh) * | 2012-04-02 | 2015-09-01 | Nat Applied Res Laboratories | 微型篩網裝置及其製造方法 |
| KR101211862B1 (ko) * | 2012-04-30 | 2012-12-12 | 한국기계연구원 | 자기장을 이용하는 자가 세포 추출장치 및 이를 이용하는 방법 |
| TWI463129B (zh) | 2012-05-07 | 2014-12-01 | Nat Applied Res Laboratories | 微粒偵測用微型篩網裝置 |
| FR2992227B1 (fr) * | 2012-06-20 | 2022-04-01 | Commissariat Energie Atomique | Ensemble de filtration pour filtrer des nanoparticules comportant un filtre et un support de filtre, appareil et procede de montage de l'ensemble associes et procede de collecte et d'analyse de nanoparticules associe. |
| US10717040B2 (en) | 2012-08-30 | 2020-07-21 | Element 1 Corp. | Hydrogen purification devices |
| US9187324B2 (en) | 2012-08-30 | 2015-11-17 | Element 1 Corp. | Hydrogen generation assemblies and hydrogen purification devices |
| US11738305B2 (en) | 2012-08-30 | 2023-08-29 | Element 1 Corp | Hydrogen purification devices |
| KR101388155B1 (ko) | 2013-03-05 | 2014-04-23 | 한국과학기술원 | 마이크로비드의 선택적 수집을 위한 마이크로비드 포획 어레이 기판 및 이의 제조 방법 |
| WO2014142754A1 (en) * | 2013-03-13 | 2014-09-18 | Cellsievo Pte Ltd | Microsieve |
| US10022659B2 (en) * | 2013-07-24 | 2018-07-17 | Aichi Prefecture | Device for isolating periphery circulating tumor cells or rare cells, and method of isolating periphery circulating tumor cells or rare cells |
| CA2946468C (en) | 2014-05-01 | 2022-10-04 | King Abdullah University Of Science And Technology | A microfluidic device that separates cells |
| EP3149469B1 (en) * | 2014-05-29 | 2020-04-22 | Siemens Healthcare Diagnostics Inc. | Rare molecule detection |
| WO2016117486A1 (ja) * | 2015-01-19 | 2016-07-28 | 株式会社村田製作所 | 多孔質構造体およびその製造方法 |
| US10996216B2 (en) | 2015-02-27 | 2021-05-04 | Toppan Printing Co., Ltd. | Method for separating cells, and device therefor |
| WO2016140183A1 (ja) * | 2015-03-05 | 2016-09-09 | 株式会社村田製作所 | 多孔体および濾過装置 |
| KR101766450B1 (ko) | 2015-04-30 | 2017-08-08 | 주식회사 싸이토젠 | 표적 세포 회수 방법 |
| WO2017022891A1 (ko) * | 2015-08-05 | 2017-02-09 | 주식회사 싸이토젠 | 세포 포집 필터 및 이를 갖는 세포 포집 장치 |
| AU2016381964B2 (en) * | 2015-12-30 | 2024-02-15 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
| WO2017119850A1 (en) * | 2016-01-08 | 2017-07-13 | Singapore University Of Technology And Design | A method of forming a thin film through-hole membrane |
| BR112018017204A2 (pt) * | 2016-03-03 | 2019-01-02 | Umezu Yasuiki | método para detectar ou separar/obter célula tumoral circulante empregando método de proliferação celular |
| US11096612B2 (en) * | 2016-04-27 | 2021-08-24 | The Hong Kong University Of Science And Technology | Methods of personalized microfiltration to detect cells from blood |
| CN109804057B (zh) | 2016-06-15 | 2022-09-09 | 米梅塔斯私人有限公司 | 细胞培养装置以及细胞培养方法 |
| CN116555028A (zh) | 2016-07-12 | 2023-08-08 | 加州理工学院 | 用于高密度细胞生长和代谢物交换的基质 |
| RU175245U1 (ru) * | 2017-01-13 | 2017-11-28 | Сергей Викторович Минаев | Сепарационное устройство для определения биохимических показателей и маркеров заболеваний в плазме крови |
| CN111343919B (zh) * | 2017-11-21 | 2023-10-10 | Bbb有限公司 | 生物传感器 |
| TWI724933B (zh) * | 2018-01-04 | 2021-04-11 | 美商1號組件公司 | 氫氣淨化裝置 |
| US11224853B2 (en) | 2018-04-11 | 2022-01-18 | W. L. Gore & Associates, Inc. | Metal supported powder catalyst matrix and processes for multiphase chemical reactions |
| CN109874316B (zh) * | 2018-05-25 | 2022-10-11 | 江苏汇先医药技术有限公司 | 用于从样本中富集筛选目标物例如细胞、细菌或生物分子的装置 |
| WO2020018925A1 (en) * | 2018-07-19 | 2020-01-23 | W.L. Gore & Associates, Inc. | High flow liquid filtration device including a porous polyparaxylylene membrane or a porous polyparaxylylene/polytetrafluoroethylene composite membrane |
| CN109554285B (zh) * | 2018-12-29 | 2024-06-28 | 北京大学 | 一种柔性微孔膜及应用其制备的细胞分离装置 |
| TWM610191U (zh) * | 2019-10-02 | 2021-04-11 | 普生股份有限公司 | 微過濾器及微過濾單元 |
| CA3163600C (en) * | 2020-01-17 | 2025-03-18 | W. L. Gore & Associates, Inc. | NANOSELECTIVE SURFACE COMPOSITE MEMBRANE FOR ORGANIC SOLVENT NANOFILTRATION |
| JP2021164532A (ja) * | 2020-04-06 | 2021-10-14 | 株式会社日立ハイテク | 多孔膜、積層体、容器、及びバイオカプセルデバイス |
| US11833477B2 (en) * | 2020-10-09 | 2023-12-05 | Global Life Sciences Solutions Usa, Llc | Tangential flow cassette-HF emulation |
| US11896934B2 (en) | 2020-12-08 | 2024-02-13 | Global Life Sciences Solutions Operations Uk Limited | Porous polymeric membrane with tear prevention ring |
| CN114018835B (zh) * | 2021-09-22 | 2023-03-17 | 浙江大学 | 微量全血预处理和血浆自动定量分配装置及分析方法 |
| EP4422787A1 (en) * | 2021-10-28 | 2024-09-04 | Southwest Research Institute | Devices for cell separation |
| CN116116221B (zh) * | 2023-01-15 | 2024-11-15 | 北京大学 | 一种多层通孔阵列滤膜、制备方法及应用 |
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| US5480552A (en) * | 1992-01-10 | 1996-01-02 | Baxter International Inc. | Method for concentrating a solute with an oscillating filtration device |
| US5985164A (en) * | 1994-03-07 | 1999-11-16 | Regents Of The University Of California | Method for forming a filter |
| EP1059979A4 (en) * | 1997-11-07 | 2001-05-30 | California Inst Of Techn | PARTICLE FILTER WITH MICRO-MACHINED MEMBRANE AND PARYLENE REINFORCEMENT |
| US6736971B2 (en) * | 2000-08-07 | 2004-05-18 | Cuno Incorporated | Pre-metered, unsupported multilayer microporous membrane |
| BR0113256A (pt) * | 2000-08-07 | 2003-07-01 | Cuno Inc | Processo para formar uma membrana microporosa e membrana microporosa com múltiplas zonas e sem suporte |
| NL1016030C1 (nl) * | 2000-08-28 | 2002-03-01 | Aquamarijn Holding B V | Sproei inrichting met een nozzleplaat, een nozzleplaat, alsmede werkwijzen ter vervaardiging en voor toepassing van een dergelijke nozzleplaat. |
| WO2004097415A1 (ja) * | 2003-04-25 | 2004-11-11 | Jsr Corporation | バイオチップおよびバイオチップキットならびにその製造方法および使用方法 |
| US7226540B2 (en) * | 2004-02-24 | 2007-06-05 | Becton, Dickinson And Company | MEMS filter module |
| CA2578539A1 (en) * | 2004-07-30 | 2006-02-09 | Hans-Werner Heinrich | Appliances and methods for cell, bio-particle and molecule sorting |
| JP4653995B2 (ja) * | 2004-10-08 | 2011-03-16 | Jsr株式会社 | バイオセパレーション用フィルターの製造方法並びにバイオセパレーション用フィルターおよびそれを用いたバイオセパレーション用キット |
| EP1888238B1 (en) * | 2005-04-21 | 2014-08-13 | California Institute of Technology | Parylene membrane filters |
| US7846393B2 (en) * | 2005-04-21 | 2010-12-07 | California Institute Of Technology | Membrane filter for capturing circulating tumor cells |
| US7846743B2 (en) * | 2005-04-21 | 2010-12-07 | California Institute Of Technology | Uses of parylene membrane filters |
| FR2902799B1 (fr) * | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
| JP5343092B2 (ja) | 2008-01-29 | 2013-11-13 | カリフォルニア インスティチュート オブ テクノロジー | 細胞分離を行う精密濾過の方法及び装置 |
-
2009
- 2009-01-26 JP JP2010545073A patent/JP5343092B2/ja active Active
- 2009-01-26 US US12/360,067 patent/US8114289B2/en active Active
- 2009-01-26 WO PCT/US2009/032054 patent/WO2009097247A1/en not_active Ceased
- 2009-01-26 EP EP09706188.1A patent/EP2238232B1/en active Active
-
2011
- 2011-12-29 US US13/340,516 patent/US8815092B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2238232B1 (en) | 2019-08-14 |
| WO2009097247A1 (en) | 2009-08-06 |
| EP2238232A1 (en) | 2010-10-13 |
| EP2238232A4 (en) | 2013-11-27 |
| US20120097610A1 (en) | 2012-04-26 |
| US20090188864A1 (en) | 2009-07-30 |
| US8815092B2 (en) | 2014-08-26 |
| JP2011510656A (ja) | 2011-04-07 |
| US8114289B2 (en) | 2012-02-14 |
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