JP5322647B2 - ウイルス感染の治療及び予防のためのシクロスポリンａのアリールアルキル及びヘテロアリールアルキル誘導体 - Google Patents
ウイルス感染の治療及び予防のためのシクロスポリンａのアリールアルキル及びヘテロアリールアルキル誘導体 Download PDFInfo
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- JP5322647B2 JP5322647B2 JP2008533791A JP2008533791A JP5322647B2 JP 5322647 B2 JP5322647 B2 JP 5322647B2 JP 2008533791 A JP2008533791 A JP 2008533791A JP 2008533791 A JP2008533791 A JP 2008533791A JP 5322647 B2 JP5322647 B2 JP 5322647B2
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72267805P | 2005-09-30 | 2005-09-30 | |
| US60/722,678 | 2005-09-30 | ||
| PCT/US2006/038822 WO2007041631A1 (en) | 2005-09-30 | 2006-10-02 | ARYIiALKYL AND HETEROARYLALKYL DERIVATIVES OF CYCLOSPORINE A FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTION |
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| JP2009510128A JP2009510128A (ja) | 2009-03-12 |
| JP2009510128A5 JP2009510128A5 (https=) | 2009-11-19 |
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| EP (1) | EP1931696B1 (https=) |
| JP (1) | JP5322647B2 (https=) |
| CN (1) | CN101316859A (https=) |
| AT (1) | ATE498630T1 (https=) |
| CA (1) | CA2623864C (https=) |
| DE (1) | DE602006020152D1 (https=) |
| WO (1) | WO2007041631A1 (https=) |
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| EP1931696B1 (en) | 2005-09-30 | 2011-02-16 | Scynexis, Inc. | Arylalkyl and heteroarylalkyl derivatives of cyclosporine a for the treatment and prevention of viral infection |
| JP5517454B2 (ja) | 2005-09-30 | 2014-06-11 | スシネキス インク | Ｃ型肝炎感染の治療及び予防のための方法及び医薬組成物 |
| EP2023918B1 (en) | 2006-05-19 | 2011-03-23 | Scynexis, Inc. | Cyclosporins for the treatment and prevention of ocular disorders |
| CN101502196A (zh) * | 2006-06-02 | 2009-08-05 | 克洛德·安妮·佩里西恩 | 激活电子的管理 |
| WO2008069917A2 (en) | 2006-11-20 | 2008-06-12 | Scynexis, Inc. | Novel cyclic peptides |
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| US20090306033A1 (en) * | 2008-06-06 | 2009-12-10 | Keqiang Li | Novel cyclic peptides |
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| BR112013014890B1 (pt) | 2010-12-15 | 2023-10-24 | Contravir Pharmaceuticals, Inc | Composto análogo de moléculas pertencentes à família ciclosporina, composição farmacêutica compreendendo o mesmo, uso terapêutico ou profilático do referido composto e processos para a preparação dos mesmos |
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- 2006-10-02 DE DE602006020152T patent/DE602006020152D1/de active Active
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- 2006-10-02 JP JP2008533791A patent/JP5322647B2/ja not_active Expired - Fee Related
- 2006-10-02 WO PCT/US2006/038822 patent/WO2007041631A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1931696A1 (en) | 2008-06-18 |
| DE602006020152D1 (de) | 2011-03-31 |
| JP2009510128A (ja) | 2009-03-12 |
| US8329658B2 (en) | 2012-12-11 |
| US20090298751A1 (en) | 2009-12-03 |
| CA2623864C (en) | 2014-12-16 |
| CN101316859A (zh) | 2008-12-03 |
| EP1931696B1 (en) | 2011-02-16 |
| CA2623864A1 (en) | 2007-04-12 |
| WO2007041631A1 (en) | 2007-04-12 |
| ATE498630T1 (de) | 2011-03-15 |
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