JP5315239B2 - Ｎ−エチルキノロンおよびｎ−エチルアザキノロンの誘導体およびアナログ - Google Patents
Ｎ−エチルキノロンおよびｎ−エチルアザキノロンの誘導体およびアナログ Download PDFInfo
- Publication number
- JP5315239B2 JP5315239B2 JP2009519978A JP2009519978A JP5315239B2 JP 5315239 B2 JP5315239 B2 JP 5315239B2 JP 2009519978 A JP2009519978 A JP 2009519978A JP 2009519978 A JP2009519978 A JP 2009519978A JP 5315239 B2 JP5315239 B2 JP 5315239B2
- Authority
- JP
- Japan
- Prior art keywords
- mmol
- dihydro
- ethyl
- stirred
- meoh
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- UKVLAIMBKUGRRQ-KPMSDPLLSA-N COc(nc1N2CCN(CC3)CC(CNCc(nc4N5)ccc4SCC5=O)[C@@H]3O)ccc1N=CC2=O Chemical compound COc(nc1N2CCN(CC3)CC(CNCc(nc4N5)ccc4SCC5=O)[C@@H]3O)ccc1N=CC2=O UKVLAIMBKUGRRQ-KPMSDPLLSA-N 0.000 description 1
- PJXAOBTZQCQEIU-MGPUTAFESA-N COc1cc(N(CCN(C[C@@H]2CNCc(nc3N4)ccc3SCC4=O)C[C@H]2O)C(C=C2)=O)c2nc1 Chemical compound COc1cc(N(CCN(C[C@@H]2CNCc(nc3N4)ccc3SCC4=O)C[C@H]2O)C(C=C2)=O)c2nc1 PJXAOBTZQCQEIU-MGPUTAFESA-N 0.000 description 1
- JYIPQGLYLYWHDM-IWPPFLRJSA-N COc1cc(N(CCN(C[C@H]2CNCc(nc3N4)ccc3OCC4=O)CC2O)C(C=C2)=O)c2nc1 Chemical compound COc1cc(N(CCN(C[C@H]2CNCc(nc3N4)ccc3OCC4=O)CC2O)C(C=C2)=O)c2nc1 JYIPQGLYLYWHDM-IWPPFLRJSA-N 0.000 description 1
- DCJPQMPOYUEPLQ-UHFFFAOYSA-N COc1ccc(C=CC(N2CCN(CC3)CCC3NCc(nn3)cc4c3OCCO4)=O)c2n1 Chemical compound COc1ccc(C=CC(N2CCN(CC3)CCC3NCc(nn3)cc4c3OCCO4)=O)c2n1 DCJPQMPOYUEPLQ-UHFFFAOYSA-N 0.000 description 1
- VKRYRLKPODCSEM-UHFFFAOYSA-N COc1ccc(C=CC(N2CCN(CC3)CCC3NCc3nnc4OCCOc4c3)=O)c2c1 Chemical compound COc1ccc(C=CC(N2CCN(CC3)CCC3NCc3nnc4OCCOc4c3)=O)c2c1 VKRYRLKPODCSEM-UHFFFAOYSA-N 0.000 description 1
- GUJNJCUEHCILSN-HRAATJIYSA-N COc1ccc(C=CC(N2CCN(C[C@@H]3CNCc(nc(c(OC4)c5)NC4=O)c5Cl)C[C@H]3O)=O)c2c1 Chemical compound COc1ccc(C=CC(N2CCN(C[C@@H]3CNCc(nc(c(OC4)c5)NC4=O)c5Cl)C[C@H]3O)=O)c2c1 GUJNJCUEHCILSN-HRAATJIYSA-N 0.000 description 1
- DQGDGZINKKKKAX-LAUBAEHRSA-N COc1ccc(C=CC(N2CCN(C[C@@H]3CNCc(nc4N5)ccc4SCC5=O)C[C@H]3O)=O)c2c1 Chemical compound COc1ccc(C=CC(N2CCN(C[C@@H]3CNCc(nc4N5)ccc4SCC5=O)C[C@H]3O)=O)c2c1 DQGDGZINKKKKAX-LAUBAEHRSA-N 0.000 description 1
- 0 Cc1nc(NC(C*CC2)=O)c2c(*)n1 Chemical compound Cc1nc(NC(C*CC2)=O)c2c(*)n1 0.000 description 1
- HFWAPQXIZOPFCD-UHFFFAOYSA-N NCC(CN(CCN(c(cc(cc1)F)c1N=C1)C1=O)CC1)C1NCc1ncc2OCCOc2c1 Chemical compound NCC(CN(CCN(c(cc(cc1)F)c1N=C1)C1=O)CC1)C1NCc1ncc2OCCOc2c1 HFWAPQXIZOPFCD-UHFFFAOYSA-N 0.000 description 1
- RRHVIQKARGNQMM-INIZCTEOSA-N O=C1Nc(nc(CNC[C@H]2CN(CCN(c3cc(F)ccc3C=C3)C3=O)CC2)cc2)c2OC1 Chemical compound O=C1Nc(nc(CNC[C@H]2CN(CCN(c3cc(F)ccc3C=C3)C3=O)CC2)cc2)c2OC1 RRHVIQKARGNQMM-INIZCTEOSA-N 0.000 description 1
- MFLXWIOANAKEHN-LAUBAEHRSA-N O[C@H]1[C@@H](CNCc(nc2N3)ccc2OCC3=O)CN(CCN(c2cc(F)ccc2C=C2)C2=O)CC1 Chemical compound O[C@H]1[C@@H](CNCc(nc2N3)ccc2OCC3=O)CN(CCN(c2cc(F)ccc2C=C2)C2=O)CC1 MFLXWIOANAKEHN-LAUBAEHRSA-N 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80785006P | 2006-07-20 | 2006-07-20 | |
| US60/807,850 | 2006-07-20 | ||
| US91305707P | 2007-04-20 | 2007-04-20 | |
| US60/913,057 | 2007-04-20 | ||
| EP07381041.8 | 2007-05-18 | ||
| EP07381041A EP1992628A1 (fr) | 2007-05-18 | 2007-05-18 | Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones |
| PCT/EP2007/057422 WO2008009700A1 (fr) | 2006-07-20 | 2007-07-18 | Dérivés et analogues de n-éthylquinolones et de n-éthylazaquinolones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009543850A JP2009543850A (ja) | 2009-12-10 |
| JP5315239B2 true JP5315239B2 (ja) | 2013-10-16 |
Family
ID=41459817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009519978A Active JP5315239B2 (ja) | 2006-07-20 | 2007-07-18 | Ｎ−エチルキノロンおよびｎ−エチルアザキノロンの誘導体およびアナログ |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JP5315239B2 (fr) |
| CR (2) | CR10587A (fr) |
| IL (1) | IL196320A (fr) |
| MA (1) | MA30640B1 (fr) |
| NZ (1) | NZ573644A (fr) |
| PE (1) | PE20081551A1 (fr) |
| TW (1) | TWI422589B (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200831517A (en) * | 2006-12-15 | 2008-08-01 | Astrazeneca Ab | Chemical compounds |
| ES2426593T3 (es) * | 2007-11-26 | 2013-10-24 | Toyama Chemical Co., Ltd. | Derivado de naftiridina monohidrato y método para producir el mismo |
| TW201209056A (en) * | 2010-05-25 | 2012-03-01 | Taisho Pharmaceutical Co Ltd | Novel heterocyclic compound or salt thereof |
| WO2019145919A1 (fr) * | 2018-01-29 | 2019-08-01 | Cadila Healthcare Limited | Composés hétérocycliques utiles en tant qu'agents antibactériens |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0934932A4 (fr) * | 1996-08-22 | 2002-06-26 | Meiji Seika Kaisha | Derives quinoleine et agent psychotrope |
| MY150958A (en) * | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| US8329694B2 (en) * | 2005-06-24 | 2012-12-11 | Toyama Chemical Co., Ltd. | Quinoxalinones as antibacterial composition |
| SG164384A1 (en) * | 2006-05-26 | 2010-09-29 | Toyama Chemical Co Ltd | Novel heterocyclic compound or salt thereof and intermediate thereof |
-
2007
- 2007-07-18 PE PE2007000927A patent/PE20081551A1/es not_active Application Discontinuation
- 2007-07-18 NZ NZ573644A patent/NZ573644A/en not_active IP Right Cessation
- 2007-07-18 JP JP2009519978A patent/JP5315239B2/ja active Active
- 2007-07-19 TW TW96126271A patent/TWI422589B/zh not_active IP Right Cessation
-
2009
- 2009-01-01 IL IL196320A patent/IL196320A/en not_active IP Right Cessation
- 2009-01-28 CR CR10587A patent/CR10587A/es not_active Application Discontinuation
- 2009-02-11 MA MA31632A patent/MA30640B1/fr unknown
-
2015
- 2015-02-17 CR CR20150080A patent/CR20150080A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TWI422589B (zh) | 2014-01-11 |
| IL196320A0 (en) | 2009-09-22 |
| NZ573644A (en) | 2011-09-30 |
| PE20081551A1 (es) | 2009-01-09 |
| JP2009543850A (ja) | 2009-12-10 |
| TW200817417A (en) | 2008-04-16 |
| CR10587A (es) | 2009-02-26 |
| IL196320A (en) | 2014-06-30 |
| MA30640B1 (fr) | 2009-08-03 |
| CR20150080A (es) | 2015-04-06 |
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