JP5301537B2 - イオントラップ、質量分析計およびその方法、並びにコンピュータ可読媒体 - Google Patents

イオントラップ、質量分析計およびその方法、並びにコンピュータ可読媒体 Download PDF

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JP5301537B2
JP5301537B2 JP2010515599A JP2010515599A JP5301537B2 JP 5301537 B2 JP5301537 B2 JP 5301537B2 JP 2010515599 A JP2010515599 A JP 2010515599A JP 2010515599 A JP2010515599 A JP 2010515599A JP 5301537 B2 JP5301537 B2 JP 5301537B2
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ions
ion trap
electrodes
electrode
ion
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Japanese (ja)
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JP2010533353A (ja
JP2010533353A5 (enExample
Inventor
グリーン・マーティン
ケニー・ダニエル・ジェイムズ
ラングリッジ・デビッド
ワイルドグース・ジェイソン・リー
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Micromass UK Ltd
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Micromass UK Ltd
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    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426Methods for controlling ions
    • H01J49/427Ejection and selection methods
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/26Mass spectrometers or separator tubes
    • H01J49/34Dynamic spectrometers
    • H01J49/42Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205Device types
    • H01J49/422Two-dimensional RF ion traps
    • H01J49/4225Multipole linear ion traps, e.g. quadrupoles, hexapoles
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
JP2010515599A 2007-07-12 2008-07-14 イオントラップ、質量分析計およびその方法、並びにコンピュータ可読媒体 Expired - Fee Related JP5301537B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0713590.8 2007-07-12
GBGB0713590.8A GB0713590D0 (en) 2007-07-12 2007-07-12 Mass spectrometer
US95197407P 2007-07-26 2007-07-26
US60/951,974 2007-07-26
PCT/GB2008/002402 WO2009007739A2 (en) 2007-07-12 2008-07-14 Mass spectrometer

Publications (3)

Publication Number Publication Date
JP2010533353A JP2010533353A (ja) 2010-10-21
JP2010533353A5 JP2010533353A5 (enExample) 2011-09-01
JP5301537B2 true JP5301537B2 (ja) 2013-09-25

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JP2010515599A Expired - Fee Related JP5301537B2 (ja) 2007-07-12 2008-07-14 イオントラップ、質量分析計およびその方法、並びにコンピュータ可読媒体

Country Status (7)

Country Link
US (3) US8426803B2 (enExample)
EP (3) EP2581927B1 (enExample)
JP (1) JP5301537B2 (enExample)
CN (1) CN101802966B (enExample)
CA (1) CA2692079C (enExample)
GB (2) GB0713590D0 (enExample)
WO (1) WO2009007739A2 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0514964D0 (en) 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
EP2038913B1 (en) 2006-07-10 2015-07-08 Micromass UK Limited Mass spectrometer
GB0624740D0 (en) * 2006-12-12 2007-01-17 Micromass Ltd Mass spectrometer
GB0713590D0 (en) * 2007-07-12 2007-08-22 Micromass Ltd Mass spectrometer
GB0810125D0 (en) 2008-06-03 2008-07-09 Thermo Fisher Scient Bremen Collosion cell
GB0900917D0 (en) 2009-01-20 2009-03-04 Micromass Ltd Mass spectrometer
GB0900973D0 (en) * 2009-01-21 2009-03-04 Micromass Ltd Method and apparatus for performing MS^N
US8541737B2 (en) * 2009-11-30 2013-09-24 Battelle Memorial Institute System and method for collisional activation of charged particles
DE102010001349B9 (de) * 2010-01-28 2014-08-28 Carl Zeiss Microscopy Gmbh Vorrichtung zum Fokussieren sowie zum Speichern von Ionen
JP5808807B2 (ja) * 2010-08-04 2015-11-10 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 放射方向振幅支援トランスファのための線形イオントラップ
WO2012025821A2 (en) * 2010-08-25 2012-03-01 Dh Technologies Development Pte. Ltd. Methods and systems for providing a substantially quadrupole field with significant hexapole and octapole components
GB201018184D0 (en) * 2010-10-27 2010-12-08 Micromass Ltd Asymmetric field ion mobility in a linear geometry ion trap
WO2012067195A1 (ja) * 2010-11-19 2012-05-24 株式会社日立ハイテクノロジーズ 質量分析装置および質量分析方法
US8581177B2 (en) * 2011-04-11 2013-11-12 Thermo Finnigan Llc High duty cycle ion storage/ion mobility separation mass spectrometer
GB201114734D0 (en) 2011-08-25 2011-10-12 Micromass Ltd Mass spectrometer
GB201116026D0 (en) 2011-09-16 2011-10-26 Micromass Ltd Performance improvements for rf-only quadrupole mass filters and linear quadrupole ion traps with axial ejection
WO2013098600A1 (en) 2011-12-27 2013-07-04 Dh Technologies Development Pte Ltd Method of extracting ions with a low m/z ratio from an ion trap
CN104335323B (zh) * 2013-01-31 2017-02-15 北京理工大学 基于离子阱的双极性离子分析与检测的装置和方法
US20150380231A1 (en) * 2013-02-18 2015-12-31 Micromass Uk Limited Improved Efficiency and Precise Control of Gas Phase Reactions in Mass Spectrometers Using an Auto Ejection Ion Trap
CN104576288B (zh) * 2013-10-28 2017-02-08 北京理工大学 一种离子连续收集装置和方法、以及离子富集系统和方法
CN106373854B (zh) * 2015-07-23 2018-12-21 株式会社岛津制作所 一种离子导引装置
CN105632878B (zh) * 2016-01-01 2017-11-17 杭州谱育科技发展有限公司 四极杆质量分析器的工作方法
CN105869986B (zh) * 2016-05-04 2017-07-25 苏州大学 一种可提高离子探测效率的质谱分析系统
GB2558221B (en) 2016-12-22 2022-07-20 Micromass Ltd Ion mobility separation exit transmission control
US10242857B2 (en) * 2017-08-31 2019-03-26 The University Of North Carolina At Chapel Hill Ion traps with Y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods
GB2573485B (en) 2017-11-20 2022-01-12 Thermo Fisher Scient Bremen Gmbh Mass spectrometer
EP3844797B1 (en) * 2018-08-29 2024-03-13 DH Technologies Development Pte. Ltd. Method for top down proteomics using exd and ptr
US11087968B2 (en) 2018-12-14 2021-08-10 Thermo Finnigan Llc. Traveling wave multipole
CN114667590B (zh) 2019-09-25 2025-03-25 印地安纳大学理事会 用于脉冲模式电荷检测质谱法的设备和方法
WO2021072186A1 (en) 2019-10-10 2021-04-15 The Trustees Of Indiana University System and method for identifying, selecting and purifying particles
US11201044B2 (en) 2020-03-03 2021-12-14 Thermo Finnigan Llc Multipole assembly configurations for reduced capacitive coupling
KR20250060291A (ko) * 2022-09-09 2025-05-07 더 트러스티즈 오브 인디애나 유니버시티 하류 분석으로부터 배출된 하전 입자의 누락을 감소시키기 위해 다극 디바이스를 제어하는 방법
CN119650129A (zh) * 2025-02-12 2025-03-18 吉林大学 一种高精度离子阱及其离子阱的组装方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783824A (en) 1995-04-03 1998-07-21 Hitachi, Ltd. Ion trapping mass spectrometry apparatus
JP3495512B2 (ja) * 1996-07-02 2004-02-09 株式会社日立製作所 イオントラップ質量分析装置
JPH11510946A (ja) * 1995-08-11 1999-09-21 エムディーエス ヘルス グループ リミテッド 軸電界を有する分光計
US6177668B1 (en) * 1996-06-06 2001-01-23 Mds Inc. Axial ejection in a multipole mass spectrometer
WO1998052209A1 (en) 1997-05-12 1998-11-19 Mds Inc. Rf-only mass spectrometer with auxiliary excitation
US6504148B1 (en) * 1999-05-27 2003-01-07 Mds Inc. Quadrupole mass spectrometer with ION traps to enhance sensitivity
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
JP4342436B2 (ja) 2002-05-30 2009-10-14 エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス 質量分析計を動作させる方法、質量分析計およびイオン・トラップ
DE10236346A1 (de) * 2002-08-08 2004-02-19 Bruker Daltonik Gmbh Nichtlinearer Resonanzauswurf aus linearen Ionenfallen
US7071464B2 (en) * 2003-03-21 2006-07-04 Dana-Farber Cancer Institute, Inc. Mass spectroscopy system
JP4223937B2 (ja) * 2003-12-16 2009-02-12 株式会社日立ハイテクノロジーズ 質量分析装置
DE602005027656D1 (de) * 2004-01-09 2011-06-09 Micromass Ltd Ionenextraktionseinrichtungen und verfahren zur selektiven extraktion von ionen
EP1889282A4 (en) 2005-05-18 2011-01-19 Mds Inc Dba Mds Sciex METHOD AND DEVICE FOR MASS-ACTIVE AXIAL TRANSPORT USING FOUR-POINT DC-DC
CN101814415B (zh) * 2005-10-31 2012-01-11 株式会社日立制作所 质量分析装置以及质量分析方法
JP5424085B2 (ja) * 2005-11-30 2014-02-26 エムディーエス インコーポレイテッド パルス軸方向場を使用した質量選択的軸方向輸送のための方法および装置
EP2038913B1 (en) 2006-07-10 2015-07-08 Micromass UK Limited Mass spectrometer
JP5081436B2 (ja) 2006-11-24 2012-11-28 株式会社日立ハイテクノロジーズ 質量分析装置及び質量分析方法
US7633060B2 (en) 2007-04-24 2009-12-15 Thermo Finnigan Llc Separation and axial ejection of ions based on m/z ratio
GB0713590D0 (en) * 2007-07-12 2007-08-22 Micromass Ltd Mass spectrometer
KR101484297B1 (ko) 2007-08-31 2015-01-19 가부시키가이샤 한도오따이 에네루기 켄큐쇼 표시장치 및 표시장치의 제작방법

Also Published As

Publication number Publication date
US8796615B2 (en) 2014-08-05
GB2455377A (en) 2009-06-10
HK1145566A1 (en) 2011-04-21
US8426803B2 (en) 2013-04-23
CA2692079C (en) 2016-07-05
EP2581927A2 (en) 2013-04-17
JP2010533353A (ja) 2010-10-21
WO2009007739A3 (en) 2009-10-29
EP2168141A2 (en) 2010-03-31
GB2455377B (en) 2010-04-28
EP2581928A2 (en) 2013-04-17
EP2581928B1 (en) 2018-09-19
CN101802966B (zh) 2013-02-27
WO2009007739A2 (en) 2009-01-15
US20100252730A1 (en) 2010-10-07
US20140131568A1 (en) 2014-05-15
CA2692079A1 (en) 2009-01-15
EP2581928A3 (en) 2013-12-25
GB0812827D0 (en) 2008-08-20
EP2168141B1 (en) 2014-06-25
CN101802966A (zh) 2010-08-11
GB0713590D0 (en) 2007-08-22
US20130221242A1 (en) 2013-08-29
EP2581927B1 (en) 2020-09-02
US8987661B2 (en) 2015-03-24
EP2581927A3 (en) 2013-12-25

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