CN101802966B - 质谱仪 - Google Patents

质谱仪 Download PDF

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Publication number
CN101802966B
CN101802966B CN2008801066691A CN200880106669A CN101802966B CN 101802966 B CN101802966 B CN 101802966B CN 2008801066691 A CN2008801066691 A CN 2008801066691A CN 200880106669 A CN200880106669 A CN 200880106669A CN 101802966 B CN101802966 B CN 101802966B
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CN
China
Prior art keywords
ion
electrode
trap device
collection
ion trap
Prior art date
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CN2008801066691A
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English (en)
Chinese (zh)
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CN101802966A (zh
Inventor
马丁·格伦
丹尼尔·詹姆斯·肯尼
大卫·兰格里奇
詹森·李·维尔德古斯
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Micromass UK Ltd
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Micromass UK Ltd
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Publication of CN101802966A publication Critical patent/CN101802966A/zh
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426—Methods for controlling ions
    • H01J49/427—Ejection and selection methods
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN2008801066691A 2007-07-12 2008-07-14 质谱仪 Active CN101802966B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0713590.8A GB0713590D0 (en) 2007-07-12 2007-07-12 Mass spectrometer
GB0713590.8 2007-07-12
US95197407P 2007-07-26 2007-07-26
US60/951,974 2007-07-26
PCT/GB2008/002402 WO2009007739A2 (en) 2007-07-12 2008-07-14 Mass spectrometer

Publications (2)

Publication Number Publication Date
CN101802966A CN101802966A (zh) 2010-08-11
CN101802966B true CN101802966B (zh) 2013-02-27

Family

ID=38461504

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801066691A Active CN101802966B (zh) 2007-07-12 2008-07-14 质谱仪

Country Status (7)

Country Link
US (3) US8426803B2 (enExample)
EP (3) EP2581927B1 (enExample)
JP (1) JP5301537B2 (enExample)
CN (1) CN101802966B (enExample)
CA (1) CA2692079C (enExample)
GB (2) GB0713590D0 (enExample)
WO (1) WO2009007739A2 (enExample)

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US8541737B2 (en) * 2009-11-30 2013-09-24 Battelle Memorial Institute System and method for collisional activation of charged particles
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JP5808807B2 (ja) * 2010-08-04 2015-11-10 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 放射方向振幅支援トランスファのための線形イオントラップ
JP5950913B2 (ja) * 2010-08-25 2016-07-13 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 有意な六重極および八重極成分を有する実質的に四重極の電場を提供するための方法およびシステム
GB201018184D0 (en) * 2010-10-27 2010-12-08 Micromass Ltd Asymmetric field ion mobility in a linear geometry ion trap
US8829434B2 (en) * 2010-11-19 2014-09-09 Hitachi High-Technologies Corporation Mass spectrometer and mass spectrometry method
US8581177B2 (en) * 2011-04-11 2013-11-12 Thermo Finnigan Llc High duty cycle ion storage/ion mobility separation mass spectrometer
GB201114734D0 (en) 2011-08-25 2011-10-12 Micromass Ltd Mass spectrometer
GB201116026D0 (en) * 2011-09-16 2011-10-26 Micromass Ltd Performance improvements for rf-only quadrupole mass filters and linear quadrupole ion traps with axial ejection
US9431230B2 (en) 2011-12-27 2016-08-30 Dh Technologies Development Pte. Ltd. Method of extracting ions with a low M/Z ratio from an ion trap
US9368336B2 (en) 2013-01-31 2016-06-14 Beijing Institute Of Technology Ion trap-based apparatus and method for analyzing and detecting bipolar ions
JP2016507151A (ja) * 2013-02-18 2016-03-07 マイクロマス ユーケー リミテッド 自動排出イオントラップを用いた質量分析器における、気相反応の改善された効率および精密制御
CN104576288B (zh) * 2013-10-28 2017-02-08 北京理工大学 一种离子连续收集装置和方法、以及离子富集系统和方法
CN106373854B (zh) * 2015-07-23 2018-12-21 株式会社岛津制作所 一种离子导引装置
CN105632878B (zh) * 2016-01-01 2017-11-17 杭州谱育科技发展有限公司 四极杆质量分析器的工作方法
CN105869986B (zh) * 2016-05-04 2017-07-25 苏州大学 一种可提高离子探测效率的质谱分析系统
GB2558221B (en) * 2016-12-22 2022-07-20 Micromass Ltd Ion mobility separation exit transmission control
US10242857B2 (en) * 2017-08-31 2019-03-26 The University Of North Carolina At Chapel Hill Ion traps with Y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods
GB2573485B (en) 2017-11-20 2022-01-12 Thermo Fisher Scient Bremen Gmbh Mass spectrometer
US11251029B2 (en) * 2018-08-29 2022-02-15 Dh Technologies Development Pte. Ltd. Method for top down proteomics using ExD and PTR
US11087968B2 (en) 2018-12-14 2021-08-10 Thermo Finnigan Llc. Traveling wave multipole
JP7671510B2 (ja) 2019-09-25 2025-05-02 ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー パルス・モード電荷検出質量分析のための装置および方法
WO2021072186A1 (en) 2019-10-10 2021-04-15 The Trustees Of Indiana University System and method for identifying, selecting and purifying particles
US11201044B2 (en) 2020-03-03 2021-12-14 Thermo Finnigan Llc Multipole assembly configurations for reduced capacitive coupling
KR20250060291A (ko) * 2022-09-09 2025-05-07 더 트러스티즈 오브 인디애나 유니버시티 하류 분석으로부터 배출된 하전 입자의 누락을 감소시키기 위해 다극 디바이스를 제어하는 방법
CN119650129A (zh) * 2025-02-12 2025-03-18 吉林大学 一种高精度离子阱及其离子阱的组装方法

Citations (1)

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US20040011956A1 (en) * 2002-05-30 2004-01-22 Londry Frank R. Methods and apparatus for reducing artifacts in mass spectrometers

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JP3495512B2 (ja) * 1996-07-02 2004-02-09 株式会社日立製作所 イオントラップ質量分析装置
CA2229070C (en) * 1995-08-11 2007-01-30 Mds Health Group Limited Spectrometer with axial field
US6177668B1 (en) * 1996-06-06 2001-01-23 Mds Inc. Axial ejection in a multipole mass spectrometer
AU7022298A (en) 1997-05-12 1998-12-08 Mds Inc. Rf-only mass spectrometer with auxiliary excitation
US6504148B1 (en) * 1999-05-27 2003-01-07 Mds Inc. Quadrupole mass spectrometer with ION traps to enhance sensitivity
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
DE10236346A1 (de) 2002-08-08 2004-02-19 Bruker Daltonik Gmbh Nichtlinearer Resonanzauswurf aus linearen Ionenfallen
US7071464B2 (en) * 2003-03-21 2006-07-04 Dana-Farber Cancer Institute, Inc. Mass spectroscopy system
JP4223937B2 (ja) * 2003-12-16 2009-02-12 株式会社日立ハイテクノロジーズ 質量分析装置
WO2005067000A2 (en) * 2004-01-09 2005-07-21 Ms Horizons Limited Ion extraction devices and methods of selectively extracting ions
JP2008541387A (ja) * 2005-05-18 2008-11-20 エムディーエス インコーポレイテッド， ドゥーイング ビジネス アズ エムディーエス サイエックス 四重極ｄｃを用いる質量選択的な軸方向輸送の方法および装置
US7675033B2 (en) * 2005-10-31 2010-03-09 Hitachi, Ltd. Method of mass spectrometry and mass spectrometer
JP5424085B2 (ja) * 2005-11-30 2014-02-26 エムディーエス インコーポレイテッド パルス軸方向場を使用した質量選択的軸方向輸送のための方法および装置
CA2656197C (en) 2006-07-10 2015-06-16 John Brian Hoyes Mass spectrometer
JP5081436B2 (ja) 2006-11-24 2012-11-28 株式会社日立ハイテクノロジーズ 質量分析装置及び質量分析方法
US7633060B2 (en) * 2007-04-24 2009-12-15 Thermo Finnigan Llc Separation and axial ejection of ions based on m/z ratio
GB0713590D0 (en) * 2007-07-12 2007-08-22 Micromass Ltd Mass spectrometer
KR101484297B1 (ko) 2007-08-31 2015-01-19 가부시키가이샤 한도오따이 에네루기 켄큐쇼 표시장치 및 표시장치의 제작방법

Patent Citations (1)

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US20040011956A1 (en) * 2002-05-30 2004-01-22 Londry Frank R. Methods and apparatus for reducing artifacts in mass spectrometers

Also Published As

Publication number Publication date
EP2581927B1 (en) 2020-09-02
CA2692079A1 (en) 2009-01-15
US20140131568A1 (en) 2014-05-15
US8987661B2 (en) 2015-03-24
GB2455377B (en) 2010-04-28
EP2581928B1 (en) 2018-09-19
EP2168141B1 (en) 2014-06-25
US20100252730A1 (en) 2010-10-07
JP5301537B2 (ja) 2013-09-25
GB0812827D0 (en) 2008-08-20
US20130221242A1 (en) 2013-08-29
CN101802966A (zh) 2010-08-11
US8426803B2 (en) 2013-04-23
EP2581928A3 (en) 2013-12-25
HK1145566A1 (en) 2011-04-21
US8796615B2 (en) 2014-08-05
EP2581927A3 (en) 2013-12-25
EP2581927A2 (en) 2013-04-17
GB2455377A (en) 2009-06-10
WO2009007739A3 (en) 2009-10-29
GB0713590D0 (en) 2007-08-22
WO2009007739A2 (en) 2009-01-15
EP2168141A2 (en) 2010-03-31
JP2010533353A (ja) 2010-10-21
CA2692079C (en) 2016-07-05
EP2581928A2 (en) 2013-04-17

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