JP5292118B2 - 蛍光内視鏡システム及び蛍光内視鏡システムの作動方法 - Google Patents

蛍光内視鏡システム及び蛍光内視鏡システムの作動方法 Download PDF

Info

Publication number
JP5292118B2
JP5292118B2 JP2009019403A JP2009019403A JP5292118B2 JP 5292118 B2 JP5292118 B2 JP 5292118B2 JP 2009019403 A JP2009019403 A JP 2009019403A JP 2009019403 A JP2009019403 A JP 2009019403A JP 5292118 B2 JP5292118 B2 JP 5292118B2
Authority
JP
Japan
Prior art keywords
fluorescence
excitation light
image information
unit
fluorescent agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2009019403A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010172530A (ja
JP2010172530A5 (https=
Inventor
牧人 小向
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Corp
Original Assignee
Fujifilm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujifilm Corp filed Critical Fujifilm Corp
Priority to JP2009019403A priority Critical patent/JP5292118B2/ja
Priority to EP10151752.2A priority patent/EP2213222B1/en
Priority to US12/696,517 priority patent/US20100194871A1/en
Publication of JP2010172530A publication Critical patent/JP2010172530A/ja
Publication of JP2010172530A5 publication Critical patent/JP2010172530A5/ja
Application granted granted Critical
Publication of JP5292118B2 publication Critical patent/JP5292118B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00064Constructional details of the endoscope body
    • A61B1/00071Insertion part of the endoscope body
    • A61B1/0008Insertion part of the endoscope body characterised by distal tip features
    • A61B1/00096Optical elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0655Control therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00186Optical arrangements with imaging filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432Quenching

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2009019403A 2009-01-30 2009-01-30 蛍光内視鏡システム及び蛍光内視鏡システムの作動方法 Expired - Fee Related JP5292118B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2009019403A JP5292118B2 (ja) 2009-01-30 2009-01-30 蛍光内視鏡システム及び蛍光内視鏡システムの作動方法
EP10151752.2A EP2213222B1 (en) 2009-01-30 2010-01-27 Fluorescence endoscope system
US12/696,517 US20100194871A1 (en) 2009-01-30 2010-01-29 Fluorescence endoscope system and fluorescence imaging method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2009019403A JP5292118B2 (ja) 2009-01-30 2009-01-30 蛍光内視鏡システム及び蛍光内視鏡システムの作動方法

Publications (3)

Publication Number Publication Date
JP2010172530A JP2010172530A (ja) 2010-08-12
JP2010172530A5 JP2010172530A5 (https=) 2011-09-15
JP5292118B2 true JP5292118B2 (ja) 2013-09-18

Family

ID=42028210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009019403A Expired - Fee Related JP5292118B2 (ja) 2009-01-30 2009-01-30 蛍光内視鏡システム及び蛍光内視鏡システムの作動方法

Country Status (3)

Country Link
US (1) US20100194871A1 (https=)
EP (1) EP2213222B1 (https=)
JP (1) JP5292118B2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5396121B2 (ja) * 2009-03-26 2014-01-22 オリンパス株式会社 画像処理装置、撮像装置、画像処理プログラムおよび画像処理装置の作動方法
JP5798430B2 (ja) 2011-10-03 2015-10-21 浜松ホトニクス株式会社 蛍光観測装置及び蛍光観測方法
JP6088181B2 (ja) * 2012-09-04 2017-03-01 Hoya株式会社 走査型共焦点内視鏡システムおよび走査型共焦点内視鏡用プロセッサ
JP6094201B2 (ja) * 2012-12-18 2017-03-15 コニカミノルタ株式会社 測定装置
JP6157135B2 (ja) * 2013-02-07 2017-07-05 オリンパス株式会社 光源撮像装置
CN103903231B (zh) * 2014-04-08 2016-09-07 西安电子科技大学 一种多光谱激发荧光成像中去除自体荧光干扰的方法
JP6814457B2 (ja) * 2016-04-19 2021-01-20 国立大学法人旭川医科大学 生体観測装置
JPWO2017221336A1 (ja) * 2016-06-21 2019-04-11 オリンパス株式会社 内視鏡システム、画像処理装置、画像処理方法およびプログラム
WO2018083879A1 (ja) * 2016-11-01 2018-05-11 オリンパス株式会社 生体観察システム
JP6892772B2 (ja) * 2017-03-17 2021-06-23 シチズン時計株式会社 歯垢検査装置
WO2020036121A1 (ja) 2018-08-17 2020-02-20 富士フイルム株式会社 内視鏡システム
US12272051B2 (en) 2019-05-28 2025-04-08 Sony Group Corporation Medical image processing apparatus, method of driving medical image processing apparatus, medical imaging system, and medical signal acquisition system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE455646B (sv) * 1984-10-22 1988-07-25 Radians Innova Ab Fluorescensanordning
JP3796635B2 (ja) * 1996-03-06 2006-07-12 富士写真フイルム株式会社 蛍光検出装置
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
DE60228165D1 (de) * 2001-05-16 2008-09-25 Olympus Corp Endoskop mit Bildverarbeitungseinrichtung
JP2003185928A (ja) * 2001-12-20 2003-07-03 Nikon Corp 照明装置及び該装置を備えた蛍光顕微鏡
AU2005284727A1 (en) * 2004-09-17 2006-03-23 University Of Massachusetts Compositions and their uses for lysosomal enzyme deficiencies
JP2006296635A (ja) * 2005-04-19 2006-11-02 Olympus Corp 内視鏡装置
JP5114024B2 (ja) * 2005-08-31 2013-01-09 オリンパス株式会社 光イメージング装置
JP2007313169A (ja) * 2006-05-29 2007-12-06 Olympus Corp 病変抽出装置および病変抽出方法
JP2008043494A (ja) * 2006-08-14 2008-02-28 Olympus Corp 蛍光内視鏡システム、蛍光観測装置、蛍光観測方法、蛍光情報処理装置、および蛍光情報処理方法

Also Published As

Publication number Publication date
US20100194871A1 (en) 2010-08-05
JP2010172530A (ja) 2010-08-12
EP2213222A1 (en) 2010-08-04
EP2213222B1 (en) 2018-11-28

Similar Documents

Publication Publication Date Title
JP5292118B2 (ja) 蛍光内視鏡システム及び蛍光内視鏡システムの作動方法
JP4954573B2 (ja) 内視鏡システム
US7919761B2 (en) Fluorescence observation apparatus
JP5208430B2 (ja) 生体組織用蛍光観察装置
CN101583304B (zh) 荧光观察装置和荧光观察方法
CN101448450B (zh) 内窥镜系统
JP4818753B2 (ja) 内視鏡システム
US20080039695A1 (en) Fluorescence endoscope system, fluoroscopy apparatus, fluoroscopy method, fluorescence-information processing apparatus, and fluorescence-information processing method
JP2008161550A (ja) 内視鏡システム
US20100036203A1 (en) Endoscope system
JP2008043396A (ja) 内視鏡システム
JP2009291554A (ja) 蛍光内視鏡装置
JP5147538B2 (ja) 蛍光画像取得装置および蛍光画像取得装置の作動方法
JP5142564B2 (ja) 蛍光内視鏡装置
JP5030513B2 (ja) 生体組織用蛍光観測装置および内視鏡システム
JP2008043383A (ja) 蛍光観察内視鏡装置
JP5030664B2 (ja) 内視鏡装置
JP2012120888A (ja) 蛍光内視鏡装置

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110802

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110802

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130219

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130227

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130426

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20130522

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130610

R150 Certificate of patent or registration of utility model

Ref document number: 5292118

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees